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OPN5 (opsin 5)

Identity

Alias_namesTMEM13
transmembrane protein 13
Alias_symbol (synonym)neuropsin
dJ402H5.1
Other aliasGPR136
GRP136
PGR12
HGNC (Hugo) OPN5
LocusID (NCBI) 221391
Atlas_Id 71136
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 47782039 and ends at 47826380 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OPN5   19992
Cards
Entrez_Gene (NCBI)OPN5  221391  opsin 5
AliasesGPR136; GRP136; PGR12; TMEM13
GeneCards (Weizmann)OPN5
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr6:47782039-47826380 [Contig_View]  OPN5 [Vega]
TCGA cBioPortalOPN5
AceView (NCBI)OPN5
Genatlas (Paris)OPN5
WikiGenes221391
SOURCE (Princeton)OPN5
Genetics Home Reference (NIH)OPN5
Genomic and cartography
GoldenPath hg38 (UCSC)OPN5  -     chr6:47782039-47826380 +  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OPN5  -     6p12.3   [Description]    (hg19-Feb_2009)
EnsemblOPN5 - 6p12.3 [CytoView hg19]  OPN5 - 6p12.3 [CytoView hg38]
Mapping of homologs : NCBIOPN5 [Mapview hg19]  OPN5 [Mapview hg38]
OMIM609042   
Gene and transcription
Genbank (Entrez)AK097448 AY255615 AY288419 AY377391 BC042544
RefSeq transcript (Entrez)NM_001030051 NM_181744
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OPN5
Cluster EST : UnigeneHs.213717 [ NCBI ]
CGAP (NCI)Hs.213717
Gene ExpressionOPN5 [ NCBI-GEO ]   OPN5 [ EBI - ARRAY_EXPRESS ]   OPN5 [ SEEK ]   OPN5 [ MEM ]
Gene Expression Viewer (FireBrowse)OPN5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221391
GTEX Portal (Tissue expression)OPN5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6U736   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6U736  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6U736
Splice isoforms : SwissVarQ6U736
PhosPhoSitePlusQ6U736
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)    OPSIN (PS00238)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Peropsin    Retinal_BS   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)OPN5
DMDM Disease mutations221391
Blocks (Seattle)OPN5
SuperfamilyQ6U736
Peptide AtlasQ6U736
HPRD12358
IPIIPI00395810   IPI00979534   IPI00967327   IPI00967591   
Protein Interaction databases
DIP (DOE-UCLA)Q6U736
IntAct (EBI)Q6U736
BioGRIDOPN5
STRING (EMBL)OPN5
ZODIACOPN5
Ontologies - Pathways
QuickGOQ6U736
Ontology : AmiGOphotoreceptor outer segment  G-protein coupled receptor activity  11-cis retinal binding  G-protein coupled receptor signaling pathway  visual perception  phototransduction  photoreceptor activity  integral component of membrane  protein-chromophore linkage  
Ontology : EGO-EBIphotoreceptor outer segment  G-protein coupled receptor activity  11-cis retinal binding  G-protein coupled receptor signaling pathway  visual perception  phototransduction  photoreceptor activity  integral component of membrane  protein-chromophore linkage  
NDEx NetworkOPN5
Atlas of Cancer Signalling NetworkOPN5
Wikipedia pathwaysOPN5
Orthology - Evolution
OrthoDB221391
Phylogenetic Trees/Animal Genes : TreeFamOPN5
HOVERGENQ6U736
HOGENOMQ6U736
Homologs : HomoloGeneOPN5
Homology/Alignments : Family Browser (UCSC)OPN5
Gene fusions - Rearrangements
Fusion : QuiverOPN5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOPN5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OPN5
dbVarOPN5
ClinVarOPN5
1000_GenomesOPN5 
Exome Variant ServerOPN5
Genetic variants : HAPMAP221391
Genomic Variants (DGV)OPN5 [DGVbeta]
DECIPHEROPN5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOPN5 
Mutations
ICGC Data PortalOPN5 
TCGA Data PortalOPN5 
Broad Tumor PortalOPN5
OASIS PortalOPN5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOPN5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOPN5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OPN5
DgiDB (Drug Gene Interaction Database)OPN5
DoCM (Curated mutations)OPN5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OPN5 (select a term)
intoGenOPN5
Cancer3DOPN5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609042   
Orphanet
DisGeNETOPN5
MedgenOPN5
Genetic Testing Registry OPN5
NextProtQ6U736 [Medical]
TSGene221391
GENETestsOPN5
Target ValidationOPN5
Huge Navigator OPN5 [HugePedia]
snp3D : Map Gene to Disease221391
BioCentury BCIQOPN5
ClinGenOPN5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221391
Chemical/Pharm GKB GenePA134942887
Clinical trialOPN5
Miscellaneous
canSAR (ICR)OPN5 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOPN5
EVEXOPN5
GoPubMedOPN5
iHOPOPN5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:45:20 CET 2018

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