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OPN5 (opsin 5)

Identity

Alias (NCBI)GPR136
GRP136
PGR12
TMEM13
HGNC (Hugo) OPN5
HGNC Alias symbneuropsin
dJ402H5.1
HGNC Alias nameneuropsin
HGNC Previous nameTMEM13
HGNC Previous nametransmembrane protein 13
LocusID (NCBI) 221391
Atlas_Id 71136
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 47782039 and ends at 47826380 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)OPN5   19992
Cards
Entrez_Gene (NCBI)OPN5    opsin 5
AliasesGPR136; GRP136; PGR12; TMEM13
GeneCards (Weizmann)OPN5
Ensembl hg19 (Hinxton)ENSG00000124818 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124818 [Gene_View]  ENSG00000124818 [Sequence]  chr6:47782039-47826380 [Contig_View]  OPN5 [Vega]
ICGC DataPortalENSG00000124818
TCGA cBioPortalOPN5
AceView (NCBI)OPN5
Genatlas (Paris)OPN5
SOURCE (Princeton)OPN5
Genetics Home Reference (NIH)OPN5
Genomic and cartography
GoldenPath hg38 (UCSC)OPN5  -     chr6:47782039-47826380 +  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OPN5  -     6p12.3   [Description]    (hg19-Feb_2009)
GoldenPathOPN5 - 6p12.3 [CytoView hg19]  OPN5 - 6p12.3 [CytoView hg38]
ImmunoBaseENSG00000124818
Genome Data Viewer NCBIOPN5 [Mapview hg19]  
OMIM609042   
Gene and transcription
Genbank (Entrez)AK097448 AY255615 AY288419 AY377391 BC042544
RefSeq transcript (Entrez)NM_001030051 NM_181744
Consensus coding sequences : CCDS (NCBI)OPN5
Gene ExpressionOPN5 [ NCBI-GEO ]   OPN5 [ EBI - ARRAY_EXPRESS ]   OPN5 [ SEEK ]   OPN5 [ MEM ]
Gene Expression Viewer (FireBrowse)OPN5 [ Firebrowse - Broad ]
GenevisibleExpression of OPN5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221391
GTEX Portal (Tissue expression)OPN5
Human Protein AtlasENSG00000124818-OPN5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6U736   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6U736  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6U736
PhosPhoSitePlusQ6U736
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)    OPSIN (PS00238)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Peropsin    Retinal_BS   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)OPN5
SuperfamilyQ6U736
AlphaFold pdb e-kbQ6U736   
Human Protein Atlas [tissue]ENSG00000124818-OPN5 [tissue]
HPRD12358
Protein Interaction databases
DIP (DOE-UCLA)Q6U736
IntAct (EBI)Q6U736
BioGRIDOPN5
STRING (EMBL)OPN5
ZODIACOPN5
Ontologies - Pathways
QuickGOQ6U736
Ontology : AmiGO11-cis retinal binding  cytoplasm  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  visual perception  phototransduction  phototransduction  phototransduction, UV  G protein-coupled photoreceptor activity  G protein-coupled photoreceptor activity  detection of visible light  protein-chromophore linkage  entrainment of circadian clock by photoperiod  cellular response to light stimulus  cellular response to light stimulus  cellular response to UV-A  hyaloid vascular plexus regression  
Ontology : EGO-EBI11-cis retinal binding  cytoplasm  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  visual perception  phototransduction  phototransduction  phototransduction, UV  G protein-coupled photoreceptor activity  G protein-coupled photoreceptor activity  detection of visible light  protein-chromophore linkage  entrainment of circadian clock by photoperiod  cellular response to light stimulus  cellular response to light stimulus  cellular response to UV-A  hyaloid vascular plexus regression  
NDEx NetworkOPN5
Atlas of Cancer Signalling NetworkOPN5
Wikipedia pathwaysOPN5
Orthology - Evolution
OrthoDB221391
GeneTree (enSembl)ENSG00000124818
Phylogenetic Trees/Animal Genes : TreeFamOPN5
Homologs : HomoloGeneOPN5
Homology/Alignments : Family Browser (UCSC)OPN5
Gene fusions - Rearrangements
Fusion : QuiverOPN5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOPN5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OPN5
dbVarOPN5
ClinVarOPN5
MonarchOPN5
1000_GenomesOPN5 
Exome Variant ServerOPN5
GNOMAD BrowserENSG00000124818
Varsome BrowserOPN5
ACMGOPN5 variants
VarityQ6U736
Genomic Variants (DGV)OPN5 [DGVbeta]
DECIPHEROPN5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOPN5 
Mutations
ICGC Data PortalOPN5 
TCGA Data PortalOPN5 
Broad Tumor PortalOPN5
OASIS PortalOPN5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOPN5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOPN5
Mutations and Diseases : HGMDOPN5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaOPN5
DgiDB (Drug Gene Interaction Database)OPN5
DoCM (Curated mutations)OPN5
CIViC (Clinical Interpretations of Variants in Cancer)OPN5
Cancer3DOPN5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609042   
Orphanet
DisGeNETOPN5
MedgenOPN5
Genetic Testing Registry OPN5
NextProtQ6U736 [Medical]
GENETestsOPN5
Target ValidationOPN5
Huge Navigator OPN5 [HugePedia]
ClinGenOPN5
Clinical trials, drugs, therapy
MyCancerGenomeOPN5
Protein Interactions : CTDOPN5
Pharm GKB GenePA134942887
PharosQ6U736
Clinical trialOPN5
Miscellaneous
canSAR (ICR)OPN5
HarmonizomeOPN5
DataMed IndexOPN5
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXOPN5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:13:38 CEST 2021

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