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OPRD1 (opioid receptor delta 1)

Identity

Alias_namesopioid receptor
Other aliasOPRD
HGNC (Hugo) OPRD1
LocusID (NCBI) 4985
Atlas_Id 51518
Location 1p35.3  [Link to chromosome band 1p35]
Location_base_pair Starts at 28812142 and ends at 28863696 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OPRD1   8153
Cards
Entrez_Gene (NCBI)OPRD1  4985  opioid receptor delta 1
AliasesOPRD
GeneCards (Weizmann)OPRD1
Ensembl hg19 (Hinxton)ENSG00000116329 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116329 [Gene_View]  chr1:28812142-28863696 [Contig_View]  OPRD1 [Vega]
ICGC DataPortalENSG00000116329
TCGA cBioPortalOPRD1
AceView (NCBI)OPRD1
Genatlas (Paris)OPRD1
WikiGenes4985
SOURCE (Princeton)OPRD1
Genetics Home Reference (NIH)OPRD1
Genomic and cartography
GoldenPath hg38 (UCSC)OPRD1  -     chr1:28812142-28863696 +  1p35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OPRD1  -     1p35.3   [Description]    (hg19-Feb_2009)
EnsemblOPRD1 - 1p35.3 [CytoView hg19]  OPRD1 - 1p35.3 [CytoView hg38]
Mapping of homologs : NCBIOPRD1 [Mapview hg19]  OPRD1 [Mapview hg38]
OMIM165195   
Gene and transcription
Genbank (Entrez)BC111838 BF434068 EF057065 EU883570 U07882
RefSeq transcript (Entrez)NM_000911
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OPRD1
Cluster EST : UnigeneHs.372 [ NCBI ]
CGAP (NCI)Hs.372
Alternative Splicing GalleryENSG00000116329
Gene ExpressionOPRD1 [ NCBI-GEO ]   OPRD1 [ EBI - ARRAY_EXPRESS ]   OPRD1 [ SEEK ]   OPRD1 [ MEM ]
Gene Expression Viewer (FireBrowse)OPRD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4985
GTEX Portal (Tissue expression)OPRD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41143   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41143  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41143
Splice isoforms : SwissVarP41143
PhosPhoSitePlusP41143
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Delta_opi_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Opioid_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)OPRD1
DMDM Disease mutations4985
Blocks (Seattle)OPRD1
PDB (SRS)1OZC    2IQM    4N6H    4RWA    4RWD   
PDB (PDBSum)1OZC    2IQM    4N6H    4RWA    4RWD   
PDB (IMB)1OZC    2IQM    4N6H    4RWA    4RWD   
PDB (RSDB)1OZC    2IQM    4N6H    4RWA    4RWD   
Structural Biology KnowledgeBase1OZC    2IQM    4N6H    4RWA    4RWD   
SCOP (Structural Classification of Proteins)1OZC    2IQM    4N6H    4RWA    4RWD   
CATH (Classification of proteins structures)1OZC    2IQM    4N6H    4RWA    4RWD   
SuperfamilyP41143
Human Protein AtlasENSG00000116329
Peptide AtlasP41143
HPRD01308
IPIIPI00298305   IPI00954796   
Protein Interaction databases
DIP (DOE-UCLA)P41143
IntAct (EBI)P41143
FunCoupENSG00000116329
BioGRIDOPRD1
STRING (EMBL)OPRD1
ZODIACOPRD1
Ontologies - Pathways
QuickGOP41143
Ontology : AmiGOprotein import into nucleus, translocation  opioid receptor activity  protein binding  cytoplasm  plasma membrane  integral component of plasma membrane  immune response  G-protein coupled receptor signaling pathway  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  chemical synaptic transmission  adult locomotory behavior  negative regulation of gene expression  sensory perception of pain  intrinsic component of plasma membrane  vesicle  negative regulation of protein oligomerization  dendrite membrane  positive regulation of CREB transcription factor activity  positive regulation of peptidyl-serine phosphorylation  opioid receptor signaling pathway  enkephalin receptor activity  eating behavior  neuropeptide binding  neuron projection  axon terminus  membrane raft  postsynaptic membrane  regulation of mitochondrial membrane potential  regulation of calcium ion transport  regulation of sensory perception of pain  cellular response to growth factor stimulus  cellular response to hypoxia  cellular response to toxic substance  
Ontology : EGO-EBIprotein import into nucleus, translocation  opioid receptor activity  protein binding  cytoplasm  plasma membrane  integral component of plasma membrane  immune response  G-protein coupled receptor signaling pathway  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  chemical synaptic transmission  adult locomotory behavior  negative regulation of gene expression  sensory perception of pain  intrinsic component of plasma membrane  vesicle  negative regulation of protein oligomerization  dendrite membrane  positive regulation of CREB transcription factor activity  positive regulation of peptidyl-serine phosphorylation  opioid receptor signaling pathway  enkephalin receptor activity  eating behavior  neuropeptide binding  neuron projection  axon terminus  membrane raft  postsynaptic membrane  regulation of mitochondrial membrane potential  regulation of calcium ion transport  regulation of sensory perception of pain  cellular response to growth factor stimulus  cellular response to hypoxia  cellular response to toxic substance  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkOPRD1
Atlas of Cancer Signalling NetworkOPRD1
Wikipedia pathwaysOPRD1
Orthology - Evolution
OrthoDB4985
GeneTree (enSembl)ENSG00000116329
Phylogenetic Trees/Animal Genes : TreeFamOPRD1
HOVERGENP41143
HOGENOMP41143
Homologs : HomoloGeneOPRD1
Homology/Alignments : Family Browser (UCSC)OPRD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOPRD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OPRD1
dbVarOPRD1
ClinVarOPRD1
1000_GenomesOPRD1 
Exome Variant ServerOPRD1
ExAC (Exome Aggregation Consortium)OPRD1 (select the gene name)
Genetic variants : HAPMAP4985
Genomic Variants (DGV)OPRD1 [DGVbeta]
DECIPHEROPRD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOPRD1 
Mutations
ICGC Data PortalOPRD1 
TCGA Data PortalOPRD1 
Broad Tumor PortalOPRD1
OASIS PortalOPRD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOPRD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOPRD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OPRD1
DgiDB (Drug Gene Interaction Database)OPRD1
DoCM (Curated mutations)OPRD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OPRD1 (select a term)
intoGenOPRD1
Cancer3DOPRD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM165195   
Orphanet
MedgenOPRD1
Genetic Testing Registry OPRD1
NextProtP41143 [Medical]
TSGene4985
GENETestsOPRD1
Target ValidationOPRD1
Huge Navigator OPRD1 [HugePedia]
snp3D : Map Gene to Disease4985
BioCentury BCIQOPRD1
ClinGenOPRD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4985
Chemical/Pharm GKB GenePA31942
Clinical trialOPRD1
Miscellaneous
canSAR (ICR)OPRD1 (select the gene name)
Probes
Litterature
PubMed115 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOPRD1
EVEXOPRD1
GoPubMedOPRD1
iHOPOPRD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:47:58 CEST 2017

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