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OPRPN (opiorphin prepropeptide)

Identity

Alias (NCBI)BPLP
PRL1
PROL1
opiorphin
HGNC (Hugo) OPRPN
HGNC Alias symbBPLP
PRL1
HGNC Previous namePROL1
HGNC Previous nameproline rich 1
 proline rich, lacrimal 1
LocusID (NCBI) 58503
Atlas_Id 78546
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 70397882 and ends at 70410197 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OPRPN   17279
Cards
Entrez_Gene (NCBI)OPRPN  58503  opiorphin prepropeptide
AliasesBPLP; PRL1; PROL1; opiorphin
GeneCards (Weizmann)OPRPN
Ensembl hg19 (Hinxton)ENSG00000171199 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171199 [Gene_View]  ENSG00000171199 [Sequence]  chr4:70397882-70410197 [Contig_View]  OPRPN [Vega]
ICGC DataPortalENSG00000171199
TCGA cBioPortalOPRPN
AceView (NCBI)OPRPN
Genatlas (Paris)OPRPN
WikiGenes58503
SOURCE (Princeton)OPRPN
Genetics Home Reference (NIH)OPRPN
Genomic and cartography
GoldenPath hg38 (UCSC)OPRPN  -     chr4:70397882-70410197 +  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OPRPN  -     4q13.3   [Description]    (hg19-Feb_2009)
GoldenPathOPRPN - 4q13.3 [CytoView hg19]  OPRPN - 4q13.3 [CytoView hg38]
ImmunoBaseENSG00000171199
genome Data Viewer NCBIOPRPN [Mapview hg19]  
OMIM608936   
Gene and transcription
Genbank (Entrez)BC092438 CD721906 CD722615 CD723077 CD723628
RefSeq transcript (Entrez)NM_001302807 NM_021225
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OPRPN
Alternative Splicing GalleryENSG00000171199
Gene ExpressionOPRPN [ NCBI-GEO ]   OPRPN [ EBI - ARRAY_EXPRESS ]   OPRPN [ SEEK ]   OPRPN [ MEM ]
Gene Expression Viewer (FireBrowse)OPRPN [ Firebrowse - Broad ]
GenevisibleExpression of OPRPN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58503
GTEX Portal (Tissue expression)OPRPN
Human Protein AtlasENSG00000171199-OPRPN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99935   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99935  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99935
Splice isoforms : SwissVarQ99935
PhosPhoSitePlusQ99935
Domains : Interpro (EBI)SMR-like   
Domain families : Pfam (Sanger)PROL5-SMR (PF15621)   
Domain families : Pfam (NCBI)pfam15621   
Conserved Domain (NCBI)OPRPN
DMDM Disease mutations58503
Blocks (Seattle)OPRPN
SuperfamilyQ99935
Human Protein Atlas [tissue]ENSG00000171199-OPRPN [tissue]
Peptide AtlasQ99935
HPRD16408
IPIIPI00009682   
Protein Interaction databases
DIP (DOE-UCLA)Q99935
IntAct (EBI)Q99935
FunCoupENSG00000171199
BioGRIDOPRPN
STRING (EMBL)OPRPN
ZODIACOPRPN
Ontologies - Pathways
QuickGOQ99935
Ontology : AmiGOretina homeostasis  endopeptidase inhibitor activity  endopeptidase inhibitor activity  extracellular region  extracellular region  extracellular space  negative regulation of endopeptidase activity  peptidase inhibitor activity  regulation of sensory perception of pain  regulation of sensory perception of pain  
Ontology : EGO-EBIretina homeostasis  endopeptidase inhibitor activity  endopeptidase inhibitor activity  extracellular region  extracellular region  extracellular space  negative regulation of endopeptidase activity  peptidase inhibitor activity  regulation of sensory perception of pain  regulation of sensory perception of pain  
NDEx NetworkOPRPN
Atlas of Cancer Signalling NetworkOPRPN
Wikipedia pathwaysOPRPN
Orthology - Evolution
OrthoDB58503
GeneTree (enSembl)ENSG00000171199
Phylogenetic Trees/Animal Genes : TreeFamOPRPN
HOGENOMQ99935
Homologs : HomoloGeneOPRPN
Homology/Alignments : Family Browser (UCSC)OPRPN
Gene fusions - Rearrangements
Fusion : QuiverOPRPN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOPRPN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OPRPN
dbVarOPRPN
ClinVarOPRPN
1000_GenomesOPRPN 
Exome Variant ServerOPRPN
GNOMAD BrowserENSG00000171199
Varsome BrowserOPRPN
Genetic variants : HAPMAP58503
Genomic Variants (DGV)OPRPN [DGVbeta]
DECIPHEROPRPN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOPRPN 
Mutations
ICGC Data PortalOPRPN 
TCGA Data PortalOPRPN 
Broad Tumor PortalOPRPN
OASIS PortalOPRPN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOPRPN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOPRPN
Mutations and Diseases : HGMDOPRPN
BioMutasearch OPRPN
DgiDB (Drug Gene Interaction Database)OPRPN
DoCM (Curated mutations)OPRPN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OPRPN (select a term)
intoGenOPRPN
Cancer3DOPRPN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608936   
Orphanet
DisGeNETOPRPN
MedgenOPRPN
Genetic Testing Registry OPRPN
NextProtQ99935 [Medical]
TSGene58503
GENETestsOPRPN
Target ValidationOPRPN
Huge Navigator OPRPN [HugePedia]
snp3D : Map Gene to Disease58503
BioCentury BCIQOPRPN
ClinGenOPRPN
Clinical trials, drugs, therapy
Protein Interactions : CTD58503
Pharm GKB GenePA33803
Clinical trialOPRPN
Miscellaneous
canSAR (ICR)OPRPN (select the gene name)
HarmonizomeOPRPN
DataMed IndexOPRPN
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOPRPN
EVEXOPRPN
GoPubMedOPRPN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Aug 22 19:29:28 CEST 2020

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