OR51E2 (olfactory receptor family 51 subfamily E member 2)

2003-02-01  

Identity

HGNC
OR51E2
LOCATION
11p15.4
LOCUSID
81285
ALIAS
HPRAJ,OR51E3P,OR52A2,PSGR
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81285
MIM: 611268
HGNC: 15195
Ensembl: ENSG00000167332

Variants:

dbSNP: 81285
ClinVar: 81285
TCGA: ENSG00000167332
COSMIC: OR51E2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167332ENST00000396950Q9H255
ENSG00000167332ENST00000396950A0A126GVK0
ENSG00000167332ENST00000532598E9PPJ8
ENSG00000167332ENST00000641638Q9H255
ENSG00000167332ENST00000641638A0A126GVK0

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Olfactory transductionKEGGko04740
Olfactory transductionKEGGhsa04740
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
Olfactory Signaling PathwayREACTOMER-HSA-381753

References

Pubmed IDYearTitleCitations
193897022009Activation of an olfactory receptor inhibits proliferation of prostate cancer cells.88
279055422016Defining an olfactory receptor function in airway smooth muscle cells.26
272266312016Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes.21
162310152006Quantitative expression profile of PSGR in prostate cancer.20
289103452017Circulating mRNAs and miRNAs as candidate markers for the diagnosis and prognosis of prostate cancer.20
164914802006The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.19
154996282005Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers.16
252195472015Quantitative phosphoproteomics reveals the protein tyrosine kinase Pyk2 as a central effector of olfactory receptor signaling in prostate cancer cells.13
281916882017Functional expression of olfactory receptors in human primary melanoma and melanoma metastasis.13
260280292016Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression.11

Citation

Dessen P

OR51E2 (olfactory receptor family 51 subfamily E member 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41610/or51e2