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ORC1 (origin recognition complex, subunit 1)

Identity

Other namesHSORC1
ORC1L
PARC1
HGNC (Hugo) ORC1
LocusID (NCBI) 4998
Location 1p32.3
Location_base_pair Starts at 52838501 and ends at 52870143 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)ORC1   8487
Cards
Entrez_Gene (NCBI)ORC1  4998  origin recognition complex, subunit 1
GeneCards (Weizmann)ORC1
Ensembl (Hinxton)ENSG00000085840 [Gene_View]  chr1:52838501-52870143 [Contig_View]  ORC1 [Vega]
ICGC DataPortalENSG00000085840
AceView (NCBI)ORC1
Genatlas (Paris)ORC1
WikiGenes4998
SOURCE (Princeton)NM_001190818 NM_001190819 NM_004153
Genomic and cartography
GoldenPath (UCSC)ORC1  -  1p32.3   chr1:52838501-52870143 -  1p32.3   [Description]    (hg19-Feb_2009)
EnsemblORC1 - 1p32.3 [CytoView]
Mapping of homologs : NCBIORC1 [Mapview]
OMIM224690   601902   
Gene and transcription
Genbank (Entrez)AK291909 AK303420 BC011539 BP280383 DB156841
RefSeq transcript (Entrez)NM_001190818 NM_001190819 NM_004153
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_028251 NT_032977 NW_001838579 NW_004929290
Consensus coding sequences : CCDS (NCBI)ORC1
Cluster EST : UnigeneHs.17908 [ NCBI ]
CGAP (NCI)Hs.17908
Alternative Splicing : Fast-db (Paris)GSHG0002104
Alternative Splicing GalleryENSG00000085840
Gene ExpressionORC1 [ NCBI-GEO ]     ORC1 [ SEEK ]   ORC1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13415 (Uniprot)
NextProtQ13415  [Medical]
With graphics : InterProQ13415
Splice isoforms : SwissVarQ13415 (Swissvar)
Domaine pattern : Prosite (Expaxy)BAH (PS51038)   
Domains : Interpro (EBI)AAA+_ATPase    ATPase_AAA_core    BAH_dom    Cdc6_C_dom    P-loop_NTPase    WHTH_DNA-bd_dom   
Related proteins : CluSTrQ13415
Domain families : Pfam (Sanger)AAA (PF00004)    BAH (PF01426)    Cdc6_C (PF09079)   
Domain families : Pfam (NCBI)pfam00004    pfam01426    pfam09079   
Domain families : Smart (EMBL)AAA (SM00382)  BAH (SM00439)  Cdc6_C (SM01074)  
DMDM Disease mutations4998
Blocks (Seattle)Q13415
Human Protein AtlasENSG00000085840
Peptide AtlasQ13415
HPRD03544
IPIIPI00013215   IPI00975911   
Protein Interaction databases
DIP (DOE-UCLA)Q13415
IntAct (EBI)Q13415
FunCoupENSG00000085840
BioGRIDORC1
InParanoidQ13415
Interologous Interaction database Q13415
IntegromeDBORC1
STRING (EMBL)ORC1
Ontologies - Pathways
Ontology : AmiGOG1/S transition of mitotic cell cycle  regulation of transcription involved in G1/S transition of mitotic cell cycle  mitotic cell cycle  origin recognition complex  DNA binding  chromatin binding  protein binding  ATP binding  nucleus  nucleoplasm  nuclear origin of replication recognition complex  nucleolus  cytoplasm  cytosol  plasma membrane  DNA replication  DNA replication initiation  nucleoside-triphosphatase activity  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  regulation of transcription involved in G1/S transition of mitotic cell cycle  mitotic cell cycle  origin recognition complex  DNA binding  chromatin binding  protein binding  ATP binding  nucleus  nucleoplasm  nuclear origin of replication recognition complex  nucleolus  cytoplasm  cytosol  plasma membrane  DNA replication  DNA replication initiation  nucleoside-triphosphatase activity  
Pathways : BIOCARTACDK Regulation of DNA Replication [Genes]   
Pathways : KEGGCell cycle   
Protein Interaction DatabaseORC1
Wikipedia pathwaysORC1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ORC1
SNP (GeneSNP Utah)ORC1
SNP : HGBaseORC1
Genetic variants : HAPMAPORC1
1000_GenomesORC1 
ICGC programENSG00000085840 
CONAN: Copy Number AnalysisORC1 
Somatic Mutations in Cancer : COSMICORC1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDORC1
OMIM224690    601902   
MedgenORC1
GENETestsORC1
Disease Genetic AssociationORC1
Huge Navigator ORC1 [HugePedia]  ORC1 [HugeCancerGEM]
Genomic VariantsORC1  ORC1 [DGVbeta]
Exome VariantORC1
dbVarORC1
ClinVarORC1
snp3D : Map Gene to Disease4998
General knowledge
Homologs : HomoloGeneORC1
Homology/Alignments : Family Browser (UCSC)ORC1
Phylogenetic Trees/Animal Genes : TreeFamORC1
Chemical/Protein Interactions : CTD4998
Chemical/Pharm GKB GenePA32808
Clinical trialORC1
Cancer Resource (Charite)ENSG00000085840
Other databases
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
CoreMineORC1
iHOPORC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:06:07 CEST 2014

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