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ORC6 (origin recognition complex subunit 6)

Identity

Other namesORC6L
HGNC (Hugo) ORC6
LocusID (NCBI) 23594
Atlas_Id 51742
Location 16q11.2
Location_base_pair Starts at 46723558 and ends at 46732306 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ORC6 (16q11.2) / CST7 (20p11.21)ORC6 (16q11.2) / VPS35 (16q11.2)USP22 (17p11.2) / ORC6 (16q11.2)
ORC6 16q11.2 / VPS35 16q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ORC6   17151
Cards
Entrez_Gene (NCBI)ORC6  23594  origin recognition complex subunit 6
AliasesORC6L
GeneCards (Weizmann)ORC6
Ensembl hg19 (Hinxton)ENSG00000091651 [Gene_View]  chr16:46723558-46732306 [Contig_View]  ORC6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000091651 [Gene_View]  chr16:46723558-46732306 [Contig_View]  ORC6 [Vega]
ICGC DataPortalENSG00000091651
TCGA cBioPortalORC6
AceView (NCBI)ORC6
Genatlas (Paris)ORC6
WikiGenes23594
SOURCE (Princeton)ORC6
Genomic and cartography
GoldenPath hg19 (UCSC)ORC6  -     chr16:46723558-46732306 +  16q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ORC6  -     16q11.2   [Description]    (hg38-Dec_2013)
EnsemblORC6 - 16q11.2 [CytoView hg19]  ORC6 - 16q11.2 [CytoView hg38]
Mapping of homologs : NCBIORC6 [Mapview hg19]  ORC6 [Mapview hg38]
OMIM607213   613803   
Gene and transcription
Genbank (Entrez)AF139658 AK021946 AK024019 AK024077 AK310633
RefSeq transcript (Entrez)NM_014321
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_028241 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)ORC6
Cluster EST : UnigeneHs.49760 [ NCBI ]
CGAP (NCI)Hs.49760
Alternative Splicing GalleryENSG00000091651
Gene ExpressionORC6 [ NCBI-GEO ]   ORC6 [ EBI - ARRAY_EXPRESS ]   ORC6 [ SEEK ]   ORC6 [ MEM ]
Gene Expression Viewer (FireBrowse)ORC6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23594
GTEX Portal (Tissue expression)ORC6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5N6 (Uniprot)
NextProtQ9Y5N6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5N6
Splice isoforms : SwissVarQ9Y5N6 (Swissvar)
PhosPhoSitePlusQ9Y5N6
Domains : Interpro (EBI)ORC6    ORC6_met/pln   
Domain families : Pfam (Sanger)ORC6 (PF05460)   
Domain families : Pfam (NCBI)pfam05460   
Domain structure : Prodom (Prabi Lyon)Origin_recog_cplx_su6-like (PD315657)   
DMDM Disease mutations23594
Blocks (Seattle)ORC6
PDB (SRS)3M03   
PDB (PDBSum)3M03   
PDB (IMB)3M03   
PDB (RSDB)3M03   
Structural Biology KnowledgeBase3M03   
SCOP (Structural Classification of Proteins)3M03   
CATH (Classification of proteins structures)3M03   
SuperfamilyQ9Y5N6
Human Protein AtlasENSG00000091651
Peptide AtlasQ9Y5N6
HPRD06237
IPIIPI00001641   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5N6
IntAct (EBI)Q9Y5N6
FunCoupENSG00000091651
BioGRIDORC6
STRING (EMBL)ORC6
ZODIACORC6
Ontologies - Pathways
QuickGOQ9Y5N6
Ontology : AmiGOG1/S transition of mitotic cell cycle  origin recognition complex  DNA binding  protein binding  nucleus  nucleoplasm  nuclear origin of replication recognition complex  DNA replication  actin cytoskeleton  membrane  aggresome  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  origin recognition complex  DNA binding  protein binding  nucleus  nucleoplasm  nuclear origin of replication recognition complex  DNA replication  actin cytoskeleton  membrane  aggresome  
Pathways : BIOCARTACDK Regulation of DNA Replication [Genes]   
Pathways : KEGGCell cycle   
NDEx Network
Atlas of Cancer Signalling NetworkORC6
Wikipedia pathwaysORC6
Orthology - Evolution
OrthoDB23594
GeneTree (enSembl)ENSG00000091651
Phylogenetic Trees/Animal Genes : TreeFamORC6
Homologs : HomoloGeneORC6
Homology/Alignments : Family Browser (UCSC)ORC6
Gene fusions - Rearrangements
Fusion: TCGAORC6 16q11.2 VPS35 16q11.2 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerORC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ORC6
dbVarORC6
ClinVarORC6
1000_GenomesORC6 
Exome Variant ServerORC6
ExAC (Exome Aggregation Consortium)ORC6 (select the gene name)
Genetic variants : HAPMAP23594
Genomic Variants (DGV)ORC6 [DGVbeta]
Mutations
ICGC Data PortalORC6 
TCGA Data PortalORC6 
Broad Tumor PortalORC6
OASIS PortalORC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICORC6 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ORC6
DgiDB (Drug Gene Interaction Database)ORC6
DoCM (Curated mutations)ORC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ORC6 (select a term)
intoGenORC6
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:46723558-46732306  ENSG00000091651
CONAN: Copy Number AnalysisORC6 
Mutations and Diseases : HGMDORC6
OMIM607213    613803   
MedgenORC6
Genetic Testing Registry ORC6
NextProtQ9Y5N6 [Medical]
TSGene23594
GENETestsORC6
Huge Navigator ORC6 [HugePedia]
snp3D : Map Gene to Disease23594
BioCentury BCIQORC6
ClinGenORC6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23594
Chemical/Pharm GKB GenePA32813
Clinical trialORC6
Miscellaneous
canSAR (ICR)ORC6 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineORC6
EVEXORC6
GoPubMedORC6
iHOPORC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 11:14:34 CEST 2016

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