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OSBP (oxysterol binding protein)

Identity

Alias_symbol (synonym)OSBP1
Other alias
HGNC (Hugo) OSBP
LocusID (NCBI) 5007
Atlas_Id 47320
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 59341871 and ends at 59383617 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DOCK8 (9p24.3) / OSBP (11q12.1)OSBP (11q12.1) / GAL (11q13.3)OSBP (11q12.1) / SRRM1 (1p36.11)
DOCK8 9p24.3 / OSBP 11q12.1OSBP 11q12.1 / GAL 11q13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OSBP   8503
Cards
Entrez_Gene (NCBI)OSBP  5007  oxysterol binding protein
AliasesOSBP1
GeneCards (Weizmann)OSBP
Ensembl hg19 (Hinxton)ENSG00000110048 [Gene_View]  chr11:59341871-59383617 [Contig_View]  OSBP [Vega]
Ensembl hg38 (Hinxton)ENSG00000110048 [Gene_View]  chr11:59341871-59383617 [Contig_View]  OSBP [Vega]
ICGC DataPortalENSG00000110048
TCGA cBioPortalOSBP
AceView (NCBI)OSBP
Genatlas (Paris)OSBP
WikiGenes5007
SOURCE (Princeton)OSBP
Genetics Home Reference (NIH)OSBP
Genomic and cartography
GoldenPath hg19 (UCSC)OSBP  -     chr11:59341871-59383617 -  11q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)OSBP  -     11q12.1   [Description]    (hg38-Dec_2013)
EnsemblOSBP - 11q12.1 [CytoView hg19]  OSBP - 11q12.1 [CytoView hg38]
Mapping of homologs : NCBIOSBP [Mapview hg19]  OSBP [Mapview hg38]
OMIM167040   
Gene and transcription
Genbank (Entrez)AF185696 AK299071 AK310538 BC011581 BC017975
RefSeq transcript (Entrez)NM_002556
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)OSBP
Cluster EST : UnigeneHs.597091 [ NCBI ]
CGAP (NCI)Hs.597091
Alternative Splicing GalleryENSG00000110048
Gene ExpressionOSBP [ NCBI-GEO ]   OSBP [ EBI - ARRAY_EXPRESS ]   OSBP [ SEEK ]   OSBP [ MEM ]
Gene Expression Viewer (FireBrowse)OSBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5007
GTEX Portal (Tissue expression)OSBP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22059   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22059  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22059
Splice isoforms : SwissVarP22059
PhosPhoSitePlusP22059
Domaine pattern : Prosite (Expaxy)OSBP (PS01013)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)Oxysterol-bd    Oxysterol-bd_CS    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)Oxysterol_BP (PF01237)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01237    pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)OSBP
DMDM Disease mutations5007
Blocks (Seattle)OSBP
PDB (SRS)2RR3   
PDB (PDBSum)2RR3   
PDB (IMB)2RR3   
PDB (RSDB)2RR3   
Structural Biology KnowledgeBase2RR3   
SCOP (Structural Classification of Proteins)2RR3   
CATH (Classification of proteins structures)2RR3   
SuperfamilyP22059
Human Protein AtlasENSG00000110048
Peptide AtlasP22059
HPRD01327
IPIIPI00024971   IPI00940548   IPI00976485   
Protein Interaction databases
DIP (DOE-UCLA)P22059
IntAct (EBI)P22059
FunCoupENSG00000110048
BioGRIDOSBP
STRING (EMBL)OSBP
ZODIACOSBP
Ontologies - Pathways
QuickGOP22059
Ontology : AmiGOGolgi membrane  protein binding  nucleus  nucleoplasm  nucleolus  cytoplasm  endoplasmic reticulum membrane  Golgi apparatus  cytosol  oxysterol binding  sterol transporter activity  sterol transport  membrane  protein domain specific binding  cell junction  positive regulation of growth of symbiont in host  perinuclear region of cytoplasm  phosphatidylinositol-4-phosphate binding  
Ontology : EGO-EBIGolgi membrane  protein binding  nucleus  nucleoplasm  nucleolus  cytoplasm  endoplasmic reticulum membrane  Golgi apparatus  cytosol  oxysterol binding  sterol transporter activity  sterol transport  membrane  protein domain specific binding  cell junction  positive regulation of growth of symbiont in host  perinuclear region of cytoplasm  phosphatidylinositol-4-phosphate binding  
NDEx NetworkOSBP
Atlas of Cancer Signalling NetworkOSBP
Wikipedia pathwaysOSBP
Orthology - Evolution
OrthoDB5007
GeneTree (enSembl)ENSG00000110048
Phylogenetic Trees/Animal Genes : TreeFamOSBP
HOVERGENP22059
HOGENOMP22059
Homologs : HomoloGeneOSBP
Homology/Alignments : Family Browser (UCSC)OSBP
Gene fusions - Rearrangements
Fusion : MitelmanDOCK8/OSBP [9p24.3/11q12.1]  [t(9;11)(p24;q12)]  
Fusion : MitelmanOSBP/GAL [11q12.1/11q13.3]  [t(11;11)(q12;q13)]  
Fusion: TCGADOCK8 9p24.3 OSBP 11q12.1 LUAD
Fusion: TCGAOSBP 11q12.1 GAL 11q13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OSBP
dbVarOSBP
ClinVarOSBP
1000_GenomesOSBP 
Exome Variant ServerOSBP
ExAC (Exome Aggregation Consortium)OSBP (select the gene name)
Genetic variants : HAPMAP5007
Genomic Variants (DGV)OSBP [DGVbeta]
DECIPHER (Syndromes)11:59341871-59383617  ENSG00000110048
CONAN: Copy Number AnalysisOSBP 
Mutations
ICGC Data PortalOSBP 
TCGA Data PortalOSBP 
Broad Tumor PortalOSBP
OASIS PortalOSBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOSBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OSBP
DgiDB (Drug Gene Interaction Database)OSBP
DoCM (Curated mutations)OSBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OSBP (select a term)
intoGenOSBP
Cancer3DOSBP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM167040   
Orphanet
MedgenOSBP
Genetic Testing Registry OSBP
NextProtP22059 [Medical]
TSGene5007
GENETestsOSBP
Huge Navigator OSBP [HugePedia]
snp3D : Map Gene to Disease5007
BioCentury BCIQOSBP
ClinGenOSBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5007
Chemical/Pharm GKB GenePA32822
Clinical trialOSBP
Miscellaneous
canSAR (ICR)OSBP (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOSBP
EVEXOSBP
GoPubMedOSBP
iHOPOSBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 15:13:11 CEST 2017

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