Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

OSBPL11 (oxysterol binding protein like 11)

Identity

Alias (NCBI)ORP-11
ORP11
OSBP12
TCCCIA00292
HGNC (Hugo) OSBPL11
HGNC Alias symbORP-11
ORP11
FLJ13012
FLJ13164
HGNC Previous nameoxysterol binding protein-like 11
LocusID (NCBI) 114885
Atlas_Id 54520
Location 3q21.2  [Link to chromosome band 3q21]
Location_base_pair Starts at 125528858 and ends at 125595497 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OSBPL11 (3q21.2) / CHCHD6 (3q21.3)PLEKHA2 (8p11.22) / OSBPL11 (3q21.2)SNX4 (3q21.2) / OSBPL11 (3q21.2)
OSBPL11 3q21.2 / CHCHD6 3q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)OSBPL11   16397
Cards
Entrez_Gene (NCBI)OSBPL11    oxysterol binding protein like 11
AliasesORP-11; ORP11; OSBP12; TCCCIA00292
GeneCards (Weizmann)OSBPL11
Ensembl hg19 (Hinxton)ENSG00000144909 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144909 [Gene_View]  ENSG00000144909 [Sequence]  chr3:125528858-125595497 [Contig_View]  OSBPL11 [Vega]
ICGC DataPortalENSG00000144909
TCGA cBioPortalOSBPL11
AceView (NCBI)OSBPL11
Genatlas (Paris)OSBPL11
SOURCE (Princeton)OSBPL11
Genetics Home Reference (NIH)OSBPL11
Genomic and cartography
GoldenPath hg38 (UCSC)OSBPL11  -     chr3:125528858-125595497 -  3q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OSBPL11  -     3q21.2   [Description]    (hg19-Feb_2009)
GoldenPathOSBPL11 - 3q21.2 [CytoView hg19]  OSBPL11 - 3q21.2 [CytoView hg38]
ImmunoBaseENSG00000144909
Genome Data Viewer NCBIOSBPL11 [Mapview hg19]  
OMIM606739   
Gene and transcription
Genbank (Entrez)AF318344 AF346292 AF392454 AK023074 AK023226
RefSeq transcript (Entrez)NM_022776
Consensus coding sequences : CCDS (NCBI)OSBPL11
Gene ExpressionOSBPL11 [ NCBI-GEO ]   OSBPL11 [ EBI - ARRAY_EXPRESS ]   OSBPL11 [ SEEK ]   OSBPL11 [ MEM ]
Gene Expression Viewer (FireBrowse)OSBPL11 [ Firebrowse - Broad ]
GenevisibleExpression of OSBPL11 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114885
GTEX Portal (Tissue expression)OSBPL11
Human Protein AtlasENSG00000144909-OSBPL11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXB4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXB4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXB4
PhosPhoSitePlusQ9BXB4
Domaine pattern : Prosite (Expaxy)OSBP (PS01013)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)OSBP_sf    Oxysterol-bd    Oxysterol-bd_CS    PH-like_dom_sf    PH_domain   
Domain families : Pfam (Sanger)Oxysterol_BP (PF01237)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01237    pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)OSBPL11
PDB (RSDB)2D9X   
PDB Europe2D9X   
PDB (PDBSum)2D9X   
PDB (IMB)2D9X   
Structural Biology KnowledgeBase2D9X   
SCOP (Structural Classification of Proteins)2D9X   
CATH (Classification of proteins structures)2D9X   
SuperfamilyQ9BXB4
AlphaFold pdb e-kbQ9BXB4   
Human Protein Atlas [tissue]ENSG00000144909-OSBPL11 [tissue]
HPRD09481
Protein Interaction databases
DIP (DOE-UCLA)Q9BXB4
IntAct (EBI)Q9BXB4
BioGRIDOSBPL11
STRING (EMBL)OSBPL11
ZODIACOSBPL11
Ontologies - Pathways
QuickGOQ9BXB4
Ontology : AmiGOprotein binding  nucleoplasm  Golgi apparatus  cytosol  positive regulation of sequestering of triglyceride  sterol transporter activity  sterol transport  membrane  late endosome membrane  sterol binding  intracellular membrane-bounded organelle  fat cell differentiation  
Ontology : EGO-EBIprotein binding  nucleoplasm  Golgi apparatus  cytosol  positive regulation of sequestering of triglyceride  sterol transporter activity  sterol transport  membrane  late endosome membrane  sterol binding  intracellular membrane-bounded organelle  fat cell differentiation  
NDEx NetworkOSBPL11
Atlas of Cancer Signalling NetworkOSBPL11
Wikipedia pathwaysOSBPL11
Orthology - Evolution
OrthoDB114885
GeneTree (enSembl)ENSG00000144909
Phylogenetic Trees/Animal Genes : TreeFamOSBPL11
Homologs : HomoloGeneOSBPL11
Homology/Alignments : Family Browser (UCSC)OSBPL11
Gene fusions - Rearrangements
Fusion : MitelmanOSBPL11/CHCHD6 [3q21.2/3q21.3]  
Fusion : MitelmanPLEKHA2/OSBPL11 [8p11.22/3q21.2]  
Fusion : QuiverOSBPL11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSBPL11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OSBPL11
dbVarOSBPL11
ClinVarOSBPL11
MonarchOSBPL11
1000_GenomesOSBPL11 
Exome Variant ServerOSBPL11
GNOMAD BrowserENSG00000144909
Varsome BrowserOSBPL11
ACMGOSBPL11 variants
VarityQ9BXB4
Genomic Variants (DGV)OSBPL11 [DGVbeta]
DECIPHEROSBPL11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOSBPL11 
Mutations
ICGC Data PortalOSBPL11 
TCGA Data PortalOSBPL11 
Broad Tumor PortalOSBPL11
OASIS PortalOSBPL11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSBPL11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOSBPL11
Mutations and Diseases : HGMDOSBPL11
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaOSBPL11
DgiDB (Drug Gene Interaction Database)OSBPL11
DoCM (Curated mutations)OSBPL11
CIViC (Clinical Interpretations of Variants in Cancer)OSBPL11
Cancer3DOSBPL11
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606739   
Orphanet
DisGeNETOSBPL11
MedgenOSBPL11
Genetic Testing Registry OSBPL11
NextProtQ9BXB4 [Medical]
GENETestsOSBPL11
Target ValidationOSBPL11
Huge Navigator OSBPL11 [HugePedia]
ClinGenOSBPL11
Clinical trials, drugs, therapy
MyCancerGenomeOSBPL11
Protein Interactions : CTDOSBPL11
Pharm GKB GenePA32825
PharosQ9BXB4
Clinical trialOSBPL11
Miscellaneous
canSAR (ICR)OSBPL11
HarmonizomeOSBPL11
DataMed IndexOSBPL11
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXOSBPL11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:23:54 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.