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OSBPL11 (oxysterol binding protein like 11)

Identity

Alias_namesoxysterol binding protein-like 11
Alias_symbol (synonym)ORP-11
ORP11
FLJ13012
FLJ13164
Other aliasOSBP12
TCCCIA00292
HGNC (Hugo) OSBPL11
LocusID (NCBI) 114885
Atlas_Id 54520
Location 3q21.2  [Link to chromosome band 3q21]
Location_base_pair Starts at 125528858 and ends at 125595537 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
OSBPL11 (3q21.2) / CHCHD6 (3q21.3)PLEKHA2 (8p11.22) / OSBPL11 (3q21.2)SNX4 (3q21.2) / OSBPL11 (3q21.2)
OSBPL11 3q21.2 / CHCHD6 3q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OSBPL11   16397
Cards
Entrez_Gene (NCBI)OSBPL11  114885  oxysterol binding protein like 11
AliasesORP-11; ORP11; OSBP12; TCCCIA00292
GeneCards (Weizmann)OSBPL11
Ensembl hg19 (Hinxton)ENSG00000144909 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144909 [Gene_View]  chr3:125528858-125595537 [Contig_View]  OSBPL11 [Vega]
ICGC DataPortalENSG00000144909
TCGA cBioPortalOSBPL11
AceView (NCBI)OSBPL11
Genatlas (Paris)OSBPL11
WikiGenes114885
SOURCE (Princeton)OSBPL11
Genetics Home Reference (NIH)OSBPL11
Genomic and cartography
GoldenPath hg38 (UCSC)OSBPL11  -     chr3:125528858-125595537 -  3q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OSBPL11  -     3q21.2   [Description]    (hg19-Feb_2009)
EnsemblOSBPL11 - 3q21.2 [CytoView hg19]  OSBPL11 - 3q21.2 [CytoView hg38]
Mapping of homologs : NCBIOSBPL11 [Mapview hg19]  OSBPL11 [Mapview hg38]
OMIM606739   
Gene and transcription
Genbank (Entrez)AF318344 AF346292 AF392454 AK023074 AK023226
RefSeq transcript (Entrez)NM_022776
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OSBPL11
Cluster EST : UnigeneHs.477440 [ NCBI ]
CGAP (NCI)Hs.477440
Alternative Splicing GalleryENSG00000144909
Gene ExpressionOSBPL11 [ NCBI-GEO ]   OSBPL11 [ EBI - ARRAY_EXPRESS ]   OSBPL11 [ SEEK ]   OSBPL11 [ MEM ]
Gene Expression Viewer (FireBrowse)OSBPL11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114885
GTEX Portal (Tissue expression)OSBPL11
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXB4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXB4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXB4
Splice isoforms : SwissVarQ9BXB4
PhosPhoSitePlusQ9BXB4
Domaine pattern : Prosite (Expaxy)OSBP (PS01013)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)Oxysterol-bd    Oxysterol-bd_CS    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)Oxysterol_BP (PF01237)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01237    pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)OSBPL11
DMDM Disease mutations114885
Blocks (Seattle)OSBPL11
PDB (SRS)2D9X   
PDB (PDBSum)2D9X   
PDB (IMB)2D9X   
PDB (RSDB)2D9X   
Structural Biology KnowledgeBase2D9X   
SCOP (Structural Classification of Proteins)2D9X   
CATH (Classification of proteins structures)2D9X   
SuperfamilyQ9BXB4
Human Protein AtlasENSG00000144909
Peptide AtlasQ9BXB4
HPRD09481
IPIIPI00032970   IPI00383306   
Protein Interaction databases
DIP (DOE-UCLA)Q9BXB4
IntAct (EBI)Q9BXB4
FunCoupENSG00000144909
BioGRIDOSBPL11
STRING (EMBL)OSBPL11
ZODIACOSBPL11
Ontologies - Pathways
QuickGOQ9BXB4
Ontology : AmiGOnucleoplasm  Golgi apparatus  lipid transport  lipid binding  positive regulation of sequestering of triglyceride  late endosome membrane  fat cell differentiation  
Ontology : EGO-EBInucleoplasm  Golgi apparatus  lipid transport  lipid binding  positive regulation of sequestering of triglyceride  late endosome membrane  fat cell differentiation  
NDEx NetworkOSBPL11
Atlas of Cancer Signalling NetworkOSBPL11
Wikipedia pathwaysOSBPL11
Orthology - Evolution
OrthoDB114885
GeneTree (enSembl)ENSG00000144909
Phylogenetic Trees/Animal Genes : TreeFamOSBPL11
HOVERGENQ9BXB4
HOGENOMQ9BXB4
Homologs : HomoloGeneOSBPL11
Homology/Alignments : Family Browser (UCSC)OSBPL11
Gene fusions - Rearrangements
Fusion : MitelmanOSBPL11/CHCHD6 [3q21.2/3q21.3]  
Fusion : MitelmanPLEKHA2/OSBPL11 [8p11.22/3q21.2]  [t(3;8)(q21;p11)]  
Fusion: TCGAOSBPL11 3q21.2 CHCHD6 3q21.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSBPL11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OSBPL11
dbVarOSBPL11
ClinVarOSBPL11
1000_GenomesOSBPL11 
Exome Variant ServerOSBPL11
ExAC (Exome Aggregation Consortium)OSBPL11 (select the gene name)
Genetic variants : HAPMAP114885
Genomic Variants (DGV)OSBPL11 [DGVbeta]
DECIPHEROSBPL11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOSBPL11 
Mutations
ICGC Data PortalOSBPL11 
TCGA Data PortalOSBPL11 
Broad Tumor PortalOSBPL11
OASIS PortalOSBPL11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSBPL11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOSBPL11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OSBPL11
DgiDB (Drug Gene Interaction Database)OSBPL11
DoCM (Curated mutations)OSBPL11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OSBPL11 (select a term)
intoGenOSBPL11
Cancer3DOSBPL11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606739   
Orphanet
MedgenOSBPL11
Genetic Testing Registry OSBPL11
NextProtQ9BXB4 [Medical]
TSGene114885
GENETestsOSBPL11
Target ValidationOSBPL11
Huge Navigator OSBPL11 [HugePedia]
snp3D : Map Gene to Disease114885
BioCentury BCIQOSBPL11
ClinGenOSBPL11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114885
Chemical/Pharm GKB GenePA32825
Clinical trialOSBPL11
Miscellaneous
canSAR (ICR)OSBPL11 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOSBPL11
EVEXOSBPL11
GoPubMedOSBPL11
iHOPOSBPL11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:48:05 CEST 2017

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