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OSBPL2 (oxysterol binding protein like 2)

Identity

Alias_namesoxysterol-binding protein-like 2
oxysterol binding protein-like 2
Alias_symbol (synonym)KIAA0772
ORP-2
DFNA67
Other aliasDNFA67
ORP2
HGNC (Hugo) OSBPL2
LocusID (NCBI) 9885
Atlas_Id 71552
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 62238485 and ends at 62296213 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
OSBPL2 (20q13.33) / CDH4 (20q13.33)OSBPL2 (20q13.33) / CELSR1 (22q13.31)OSBPL2 (20q13.33) / DLGAP4 (20q11.23)
OSBPL2 (20q13.33) / OSBPL2 (20q13.33)OSBPL2 (20q13.33) / PLD1 (3q26.31)TTC31 (2p13.1) / OSBPL2 (20q13.33)
OSBPL2 CDH4OSBPL2 PLD1OSBPL2 DLGAP4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OSBPL2   15761
Cards
Entrez_Gene (NCBI)OSBPL2  9885  oxysterol binding protein like 2
AliasesDFNA67; DNFA67; ORP-2; ORP2
GeneCards (Weizmann)OSBPL2
Ensembl hg19 (Hinxton)ENSG00000130703 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130703 [Gene_View]  chr20:62238485-62296213 [Contig_View]  OSBPL2 [Vega]
ICGC DataPortalENSG00000130703
TCGA cBioPortalOSBPL2
AceView (NCBI)OSBPL2
Genatlas (Paris)OSBPL2
WikiGenes9885
SOURCE (Princeton)OSBPL2
Genetics Home Reference (NIH)OSBPL2
Genomic and cartography
GoldenPath hg38 (UCSC)OSBPL2  -     chr20:62238485-62296213 +  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OSBPL2  -     20q13.33   [Description]    (hg19-Feb_2009)
EnsemblOSBPL2 - 20q13.33 [CytoView hg19]  OSBPL2 - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBIOSBPL2 [Mapview hg19]  OSBPL2 [Mapview hg38]
OMIM606731   616340   
Gene and transcription
Genbank (Entrez)AB018315 AF331963 AF392447 AK000230 AK093592
RefSeq transcript (Entrez)NM_001001691 NM_001278649 NM_014835 NM_144498
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OSBPL2
Cluster EST : UnigeneHs.473254 [ NCBI ]
CGAP (NCI)Hs.473254
Alternative Splicing GalleryENSG00000130703
Gene ExpressionOSBPL2 [ NCBI-GEO ]   OSBPL2 [ EBI - ARRAY_EXPRESS ]   OSBPL2 [ SEEK ]   OSBPL2 [ MEM ]
Gene Expression Viewer (FireBrowse)OSBPL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9885
GTEX Portal (Tissue expression)OSBPL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1P3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H1P3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H1P3
Splice isoforms : SwissVarQ9H1P3
PhosPhoSitePlusQ9H1P3
Domaine pattern : Prosite (Expaxy)OSBP (PS01013)   
Domains : Interpro (EBI)Oxysterol-bd    Oxysterol-bd_CS   
Domain families : Pfam (Sanger)Oxysterol_BP (PF01237)   
Domain families : Pfam (NCBI)pfam01237   
Conserved Domain (NCBI)OSBPL2
DMDM Disease mutations9885
Blocks (Seattle)OSBPL2
SuperfamilyQ9H1P3
Human Protein AtlasENSG00000130703
Peptide AtlasQ9H1P3
HPRD09473
IPIIPI00014137   IPI00220460   IPI00909312   IPI00001098   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1P3
IntAct (EBI)Q9H1P3
FunCoupENSG00000130703
BioGRIDOSBPL2
STRING (EMBL)OSBPL2
ZODIACOSBPL2
Ontologies - Pathways
QuickGOQ9H1P3
Ontology : AmiGOprotein binding  cytosol  bile acid biosynthetic process  sterol transporter activity  cholesterol binding  sterol transport  
Ontology : EGO-EBIprotein binding  cytosol  bile acid biosynthetic process  sterol transporter activity  cholesterol binding  sterol transport  
NDEx NetworkOSBPL2
Atlas of Cancer Signalling NetworkOSBPL2
Wikipedia pathwaysOSBPL2
Orthology - Evolution
OrthoDB9885
GeneTree (enSembl)ENSG00000130703
Phylogenetic Trees/Animal Genes : TreeFamOSBPL2
HOVERGENQ9H1P3
HOGENOMQ9H1P3
Homologs : HomoloGeneOSBPL2
Homology/Alignments : Family Browser (UCSC)OSBPL2
Gene fusions - Rearrangements
Fusion: TCGAOSBPL2 CDH4
Fusion: TCGAOSBPL2 PLD1
Fusion: TCGAOSBPL2 DLGAP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSBPL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OSBPL2
dbVarOSBPL2
ClinVarOSBPL2
1000_GenomesOSBPL2 
Exome Variant ServerOSBPL2
ExAC (Exome Aggregation Consortium)OSBPL2 (select the gene name)
Genetic variants : HAPMAP9885
Genomic Variants (DGV)OSBPL2 [DGVbeta]
DECIPHEROSBPL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOSBPL2 
Mutations
ICGC Data PortalOSBPL2 
TCGA Data PortalOSBPL2 
Broad Tumor PortalOSBPL2
OASIS PortalOSBPL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSBPL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOSBPL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OSBPL2
DgiDB (Drug Gene Interaction Database)OSBPL2
DoCM (Curated mutations)OSBPL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OSBPL2 (select a term)
intoGenOSBPL2
Cancer3DOSBPL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606731    616340   
Orphanet12046   
MedgenOSBPL2
Genetic Testing Registry OSBPL2
NextProtQ9H1P3 [Medical]
TSGene9885
GENETestsOSBPL2
Target ValidationOSBPL2
Huge Navigator OSBPL2 [HugePedia]
snp3D : Map Gene to Disease9885
BioCentury BCIQOSBPL2
ClinGenOSBPL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9885
Chemical/Pharm GKB GenePA32827
Clinical trialOSBPL2
Miscellaneous
canSAR (ICR)OSBPL2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOSBPL2
EVEXOSBPL2
GoPubMedOSBPL2
iHOPOSBPL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:33:43 CEST 2017

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