Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

OSBPL3 (oxysterol binding protein like 3)

Identity

Alias_namesOSBP3
oxysterol binding protein-like 3
Alias_symbol (synonym)ORP-3
ORP3
KIAA0704
Other alias
HGNC (Hugo) OSBPL3
LocusID (NCBI) 26031
Atlas_Id 71553
Location 7p15.3  [Link to chromosome band 7p15]
Location_base_pair Starts at 24796537 and ends at 24980212 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACTB (7p22.1) / OSBPL3 (7p15.3)ATP6V0A1 (17q21.2) / OSBPL3 (7p15.3)CCDC126 (7p15.3) / OSBPL3 (7p15.3)
MPP6 (7p15.3) / OSBPL3 (7p15.3)OSBPL3 (7p15.3) / CORIN (4p12)OSBPL3 (7p15.3) / FOXA1 (14q21.1)
OSBPL3 (7p15.3) / GABRG3 (15q12)PCNP (3q12.3) / OSBPL3 (7p15.3)OSBPL3 CORIN
OSBPL3 GABRG3MPP6 OSBPL3CCDC126 OSBPL3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OSBPL3   16370
Cards
Entrez_Gene (NCBI)OSBPL3  26031  oxysterol binding protein like 3
AliasesORP-3; ORP3; OSBP3
GeneCards (Weizmann)OSBPL3
Ensembl hg19 (Hinxton)ENSG00000070882 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000070882 [Gene_View]  chr7:24796537-24980212 [Contig_View]  OSBPL3 [Vega]
ICGC DataPortalENSG00000070882
TCGA cBioPortalOSBPL3
AceView (NCBI)OSBPL3
Genatlas (Paris)OSBPL3
WikiGenes26031
SOURCE (Princeton)OSBPL3
Genetics Home Reference (NIH)OSBPL3
Genomic and cartography
GoldenPath hg38 (UCSC)OSBPL3  -     chr7:24796537-24980212 -  7p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OSBPL3  -     7p15.3   [Description]    (hg19-Feb_2009)
EnsemblOSBPL3 - 7p15.3 [CytoView hg19]  OSBPL3 - 7p15.3 [CytoView hg38]
Mapping of homologs : NCBIOSBPL3 [Mapview hg19]  OSBPL3 [Mapview hg38]
OMIM606732   
Gene and transcription
Genbank (Entrez)AB014604 AF323727 AF392444 AF491781 AF491782
RefSeq transcript (Entrez)NM_015550 NM_145320 NM_145321 NM_145322 NM_145323 NM_145324
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OSBPL3
Cluster EST : UnigeneHs.520259 [ NCBI ]
CGAP (NCI)Hs.520259
Alternative Splicing GalleryENSG00000070882
Gene ExpressionOSBPL3 [ NCBI-GEO ]   OSBPL3 [ EBI - ARRAY_EXPRESS ]   OSBPL3 [ SEEK ]   OSBPL3 [ MEM ]
Gene Expression Viewer (FireBrowse)OSBPL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26031
GTEX Portal (Tissue expression)OSBPL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4L5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4L5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4L5
Splice isoforms : SwissVarQ9H4L5
PhosPhoSitePlusQ9H4L5
Domaine pattern : Prosite (Expaxy)OSBP (PS01013)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)Oxysterol-bd    Oxysterol-bd_CS    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)Oxysterol_BP (PF01237)   
Domain families : Pfam (NCBI)pfam01237   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)OSBPL3
DMDM Disease mutations26031
Blocks (Seattle)OSBPL3
SuperfamilyQ9H4L5
Human Protein AtlasENSG00000070882
Peptide AtlasQ9H4L5
HPRD09474
IPIIPI00023555   IPI00167053   IPI00162669   IPI00162670   IPI00169299   IPI00169296   IPI00375694   IPI00375695   IPI00915900   IPI00915756   IPI00917958   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4L5
IntAct (EBI)Q9H4L5
FunCoupENSG00000070882
BioGRIDOSBPL3
STRING (EMBL)OSBPL3
ZODIACOSBPL3
Ontologies - Pathways
QuickGOQ9H4L5
Ontology : AmiGOprotein binding  endoplasmic reticulum membrane  cytosol  cytosol  plasma membrane  bile acid biosynthetic process  sterol transporter activity  cholesterol binding  sterol transport  membrane  nuclear membrane  filopodium tip  perinuclear endoplasmic reticulum  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum membrane  cytosol  cytosol  plasma membrane  bile acid biosynthetic process  sterol transporter activity  cholesterol binding  sterol transport  membrane  nuclear membrane  filopodium tip  perinuclear endoplasmic reticulum  
NDEx NetworkOSBPL3
Atlas of Cancer Signalling NetworkOSBPL3
Wikipedia pathwaysOSBPL3
Orthology - Evolution
OrthoDB26031
GeneTree (enSembl)ENSG00000070882
Phylogenetic Trees/Animal Genes : TreeFamOSBPL3
HOVERGENQ9H4L5
HOGENOMQ9H4L5
Homologs : HomoloGeneOSBPL3
Homology/Alignments : Family Browser (UCSC)OSBPL3
Gene fusions - Rearrangements
Fusion: TCGAOSBPL3 CORIN
Fusion: TCGAOSBPL3 GABRG3
Fusion: TCGAMPP6 OSBPL3
Fusion: TCGACCDC126 OSBPL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSBPL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OSBPL3
dbVarOSBPL3
ClinVarOSBPL3
1000_GenomesOSBPL3 
Exome Variant ServerOSBPL3
ExAC (Exome Aggregation Consortium)OSBPL3 (select the gene name)
Genetic variants : HAPMAP26031
Genomic Variants (DGV)OSBPL3 [DGVbeta]
DECIPHEROSBPL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOSBPL3 
Mutations
ICGC Data PortalOSBPL3 
TCGA Data PortalOSBPL3 
Broad Tumor PortalOSBPL3
OASIS PortalOSBPL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSBPL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOSBPL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OSBPL3
DgiDB (Drug Gene Interaction Database)OSBPL3
DoCM (Curated mutations)OSBPL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OSBPL3 (select a term)
intoGenOSBPL3
Cancer3DOSBPL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606732   
Orphanet
MedgenOSBPL3
Genetic Testing Registry OSBPL3
NextProtQ9H4L5 [Medical]
TSGene26031
GENETestsOSBPL3
Target ValidationOSBPL3
Huge Navigator OSBPL3 [HugePedia]
snp3D : Map Gene to Disease26031
BioCentury BCIQOSBPL3
ClinGenOSBPL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26031
Chemical/Pharm GKB GenePA32828
Clinical trialOSBPL3
Miscellaneous
canSAR (ICR)OSBPL3 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOSBPL3
EVEXOSBPL3
GoPubMedOSBPL3
iHOPOSBPL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:35:11 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.