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OSR2 (odd-skipped related transciption factor 2)

Identity

Alias_namesodd-skipped related 2 (Drosophila)
Alias_symbol (synonym)FLJ90037
Other alias-
HGNC (Hugo) OSR2
LocusID (NCBI) 116039
Atlas_Id 56284
Location 8q22.2  [Link to chromosome band 8q22]
Location_base_pair Starts at 98944403 and ends at 98952104 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EEF2 (19p13.3) / OSR2 (8q22.2)OSR2 (8q22.2) / GOLIM4 (3q26.2)VPS13B (8q22.2) / OSR2 (8q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OSR2   15830
Cards
Entrez_Gene (NCBI)OSR2  116039  odd-skipped related transciption factor 2
Aliases
GeneCards (Weizmann)OSR2
Ensembl hg19 (Hinxton)ENSG00000164920 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164920 [Gene_View]  chr8:98944403-98952104 [Contig_View]  OSR2 [Vega]
ICGC DataPortalENSG00000164920
TCGA cBioPortalOSR2
AceView (NCBI)OSR2
Genatlas (Paris)OSR2
WikiGenes116039
SOURCE (Princeton)OSR2
Genetics Home Reference (NIH)OSR2
Genomic and cartography
GoldenPath hg38 (UCSC)OSR2  -     chr8:98944403-98952104 +  8q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OSR2  -     8q22.2   [Description]    (hg19-Feb_2009)
EnsemblOSR2 - 8q22.2 [CytoView hg19]  OSR2 - 8q22.2 [CytoView hg38]
Mapping of homologs : NCBIOSR2 [Mapview hg19]  OSR2 [Mapview hg38]
OMIM611297   
Gene and transcription
Genbank (Entrez)AK074518 AK291491 AK304654 AK310994 AY038072
RefSeq transcript (Entrez)NM_001142462 NM_001286841 NM_053001
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OSR2
Cluster EST : UnigeneHs.253247 [ NCBI ]
CGAP (NCI)Hs.253247
Alternative Splicing GalleryENSG00000164920
Gene ExpressionOSR2 [ NCBI-GEO ]   OSR2 [ EBI - ARRAY_EXPRESS ]   OSR2 [ SEEK ]   OSR2 [ MEM ]
Gene Expression Viewer (FireBrowse)OSR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116039
GTEX Portal (Tissue expression)OSR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N2R0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N2R0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N2R0
Splice isoforms : SwissVarQ8N2R0
PhosPhoSitePlusQ8N2R0
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)    zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam00096    pfam13912   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)OSR2
DMDM Disease mutations116039
Blocks (Seattle)OSR2
SuperfamilyQ8N2R0
Human Protein AtlasENSG00000164920
Peptide AtlasQ8N2R0
HPRD17806
IPIIPI00943317   IPI00719002   IPI00170991   IPI00981227   IPI00980039   IPI00974272   
Protein Interaction databases
DIP (DOE-UCLA)Q8N2R0
IntAct (EBI)Q8N2R0
FunCoupENSG00000164920
BioGRIDOSR2
STRING (EMBL)OSR2
ZODIACOSR2
Ontologies - Pathways
QuickGOQ8N2R0
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  metanephros development  mesonephros development  chondrocyte differentiation  protein binding  nucleus  positive regulation of cell proliferation  embryo development  positive regulation of gene expression  cell differentiation  positive regulation of bone mineralization  osteoblast proliferation  embryonic forelimb morphogenesis  embryonic hindlimb morphogenesis  embryonic skeletal limb joint morphogenesis  middle ear morphogenesis  odontogenesis  embryonic digit morphogenesis  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  embryonic skeletal system morphogenesis  positive regulation of epithelial cell proliferation  palate development  embryonic skeletal joint morphogenesis  head development  bone morphogenesis  eyelid development in camera-type eye  embryonic skeletal joint development  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  metanephros development  mesonephros development  chondrocyte differentiation  protein binding  nucleus  positive regulation of cell proliferation  embryo development  positive regulation of gene expression  cell differentiation  positive regulation of bone mineralization  osteoblast proliferation  embryonic forelimb morphogenesis  embryonic hindlimb morphogenesis  embryonic skeletal limb joint morphogenesis  middle ear morphogenesis  odontogenesis  embryonic digit morphogenesis  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  embryonic skeletal system morphogenesis  positive regulation of epithelial cell proliferation  palate development  embryonic skeletal joint morphogenesis  head development  bone morphogenesis  eyelid development in camera-type eye  embryonic skeletal joint development  
NDEx NetworkOSR2
Atlas of Cancer Signalling NetworkOSR2
Wikipedia pathwaysOSR2
Orthology - Evolution
OrthoDB116039
GeneTree (enSembl)ENSG00000164920
Phylogenetic Trees/Animal Genes : TreeFamOSR2
HOVERGENQ8N2R0
HOGENOMQ8N2R0
Homologs : HomoloGeneOSR2
Homology/Alignments : Family Browser (UCSC)OSR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OSR2
dbVarOSR2
ClinVarOSR2
1000_GenomesOSR2 
Exome Variant ServerOSR2
ExAC (Exome Aggregation Consortium)OSR2 (select the gene name)
Genetic variants : HAPMAP116039
Genomic Variants (DGV)OSR2 [DGVbeta]
DECIPHEROSR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOSR2 
Mutations
ICGC Data PortalOSR2 
TCGA Data PortalOSR2 
Broad Tumor PortalOSR2
OASIS PortalOSR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOSR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OSR2
DgiDB (Drug Gene Interaction Database)OSR2
DoCM (Curated mutations)OSR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OSR2 (select a term)
intoGenOSR2
Cancer3DOSR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611297   
Orphanet
MedgenOSR2
Genetic Testing Registry OSR2
NextProtQ8N2R0 [Medical]
TSGene116039
GENETestsOSR2
Target ValidationOSR2
Huge Navigator OSR2 [HugePedia]
snp3D : Map Gene to Disease116039
BioCentury BCIQOSR2
ClinGenOSR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116039
Chemical/Pharm GKB GenePA134924513
Clinical trialOSR2
Miscellaneous
canSAR (ICR)OSR2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOSR2
EVEXOSR2
GoPubMedOSR2
iHOPOSR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:09:49 CEST 2017

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