Atlas of Genetics and Cytogenetics in Oncology and Haematology

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OSTF1 (osteoclast stimulating factor 1)

Identity

Alias (NCBI)OSF
SH3P2
bA235O14.1
HGNC (Hugo) OSTF1
HGNC Alias symbSH3P2
OSF
bA235O14.1
LocusID (NCBI) 26578
Atlas_Id 56037
Location 9q21.13  [Link to chromosome band 9q21]
Location_base_pair Starts at 75088514 and ends at 75147265 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC117 (22q12.1) / OSTF1 (9q21.13)OSTF1 (9q21.13) / SYNE2 (14q23.2)PCSK5 (9q21.13) / OSTF1 (9q21.13)
RASEF (9q21.32) / OSTF1 (9q21.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)OSTF1   8510
Cards
Entrez_Gene (NCBI)OSTF1    osteoclast stimulating factor 1
AliasesOSF; SH3P2; bA235O14.1
GeneCards (Weizmann)OSTF1
Ensembl hg19 (Hinxton)ENSG00000134996 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134996 [Gene_View]  ENSG00000134996 [Sequence]  chr9:75088514-75147265 [Contig_View]  OSTF1 [Vega]
ICGC DataPortalENSG00000134996
TCGA cBioPortalOSTF1
AceView (NCBI)OSTF1
Genatlas (Paris)OSTF1
SOURCE (Princeton)OSTF1
Genetics Home Reference (NIH)OSTF1
Genomic and cartography
GoldenPath hg38 (UCSC)OSTF1  -     chr9:75088514-75147265 +  9q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OSTF1  -     9q21.13   [Description]    (hg19-Feb_2009)
GoldenPathOSTF1 - 9q21.13 [CytoView hg19]  OSTF1 - 9q21.13 [CytoView hg38]
ImmunoBaseENSG00000134996
genome Data Viewer NCBIOSTF1 [Mapview hg19]  
OMIM610180   
Gene and transcription
Genbank (Entrez)AK222596 AK291511 BC007459 BP312980 U63717
RefSeq transcript (Entrez)NM_012383
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OSTF1
Alternative Splicing GalleryENSG00000134996
Gene ExpressionOSTF1 [ NCBI-GEO ]   OSTF1 [ EBI - ARRAY_EXPRESS ]   OSTF1 [ SEEK ]   OSTF1 [ MEM ]
Gene Expression Viewer (FireBrowse)OSTF1 [ Firebrowse - Broad ]
GenevisibleExpression of OSTF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26578
GTEX Portal (Tissue expression)OSTF1
Human Protein AtlasENSG00000134996-OSTF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92882   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92882  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92882
Splice isoforms : SwissVarQ92882
PhosPhoSitePlusQ92882
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    SH3 (PS50002)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ankyrin_rpt-contain_sf    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam12796    pfam00018   
Domain families : Smart (EMBL)ANK (SM00248)  SH3 (SM00326)  
Conserved Domain (NCBI)OSTF1
Blocks (Seattle)OSTF1
PDB (RSDB)1X2K    1ZLM    3EHQ    3EHR   
PDB Europe1X2K    1ZLM    3EHQ    3EHR   
PDB (PDBSum)1X2K    1ZLM    3EHQ    3EHR   
PDB (IMB)1X2K    1ZLM    3EHQ    3EHR   
Structural Biology KnowledgeBase1X2K    1ZLM    3EHQ    3EHR   
SCOP (Structural Classification of Proteins)1X2K    1ZLM    3EHQ    3EHR   
CATH (Classification of proteins structures)1X2K    1ZLM    3EHQ    3EHR   
SuperfamilyQ92882
Human Protein Atlas [tissue]ENSG00000134996-OSTF1 [tissue]
Peptide AtlasQ92882
HPRD17808
IPIIPI00414836   
Protein Interaction databases
DIP (DOE-UCLA)Q92882
IntAct (EBI)Q92882
BioGRIDOSTF1
STRING (EMBL)OSTF1
ZODIACOSTF1
Ontologies - Pathways
QuickGOQ92882
Ontology : AmiGOossification  protein binding  extracellular region  extracellular region  intracellular anatomical structure  signal transduction  SH3 domain binding  secretory granule lumen  neutrophil degranulation  ficolin-1-rich granule lumen  
Ontology : EGO-EBIossification  protein binding  extracellular region  extracellular region  intracellular anatomical structure  signal transduction  SH3 domain binding  secretory granule lumen  neutrophil degranulation  ficolin-1-rich granule lumen  
NDEx NetworkOSTF1
Atlas of Cancer Signalling NetworkOSTF1
Wikipedia pathwaysOSTF1
Orthology - Evolution
OrthoDB26578
GeneTree (enSembl)ENSG00000134996
Phylogenetic Trees/Animal Genes : TreeFamOSTF1
HOGENOMQ92882
Homologs : HomoloGeneOSTF1
Homology/Alignments : Family Browser (UCSC)OSTF1
Gene fusions - Rearrangements
Fusion : QuiverOSTF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSTF1 [hg38]
dbVarOSTF1
ClinVarOSTF1
MonarchOSTF1
1000_GenomesOSTF1 
Exome Variant ServerOSTF1
GNOMAD BrowserENSG00000134996
Varsome BrowserOSTF1
Genomic Variants (DGV)OSTF1 [DGVbeta]
DECIPHEROSTF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOSTF1 
Mutations
ICGC Data PortalOSTF1 
TCGA Data PortalOSTF1 
Broad Tumor PortalOSTF1
OASIS PortalOSTF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSTF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOSTF1
Mutations and Diseases : HGMDOSTF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OSTF1
DgiDB (Drug Gene Interaction Database)OSTF1
DoCM (Curated mutations)OSTF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OSTF1 (select a term)
intoGenOSTF1
Cancer3DOSTF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610180   
Orphanet
DisGeNETOSTF1
MedgenOSTF1
Genetic Testing Registry OSTF1
NextProtQ92882 [Medical]
GENETestsOSTF1
Target ValidationOSTF1
Huge Navigator OSTF1 [HugePedia]
ClinGenOSTF1
Clinical trials, drugs, therapy
MyCancerGenomeOSTF1
Protein Interactions : CTD
Pharm GKB GenePA32839
PharosQ92882
Clinical trialOSTF1
Miscellaneous
canSAR (ICR)OSTF1 (select the gene name)
HarmonizomeOSTF1
DataMed IndexOSTF1
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXOSTF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:37:50 CET 2021
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