Atlas of Genetics and Cytogenetics in Oncology and Haematology


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OSTN (osteocrin)

Identity

Other aliasMUSCLIN
HGNC (Hugo) OSTN
LocusID (NCBI) 344901
Atlas_Id 71571
Location 3q28  [Link to chromosome band 3q28]
Location_base_pair Starts at 191199241 and ends at 191265614 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OSTN   29961
Cards
Entrez_Gene (NCBI)OSTN  344901  osteocrin
AliasesMUSCLIN
GeneCards (Weizmann)OSTN
Ensembl hg19 (Hinxton)ENSG00000188729 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188729 [Gene_View]  chr3:191199241-191265614 [Contig_View]  OSTN [Vega]
ICGC DataPortalENSG00000188729
TCGA cBioPortalOSTN
AceView (NCBI)OSTN
Genatlas (Paris)OSTN
WikiGenes344901
SOURCE (Princeton)OSTN
Genetics Home Reference (NIH)OSTN
Genomic and cartography
GoldenPath hg38 (UCSC)OSTN  -     chr3:191199241-191265614 +  3q28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OSTN  -     3q28   [Description]    (hg19-Feb_2009)
EnsemblOSTN - 3q28 [CytoView hg19]  OSTN - 3q28 [CytoView hg38]
Mapping of homologs : NCBIOSTN [Mapview hg19]  OSTN [Mapview hg38]
OMIM610280   
Gene and transcription
Genbank (Entrez)AY398681 AY573933 BC128106 BC128107
RefSeq transcript (Entrez)NM_198184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OSTN
Cluster EST : UnigeneHs.526794 [ NCBI ]
CGAP (NCI)Hs.526794
Alternative Splicing GalleryENSG00000188729
Gene ExpressionOSTN [ NCBI-GEO ]   OSTN [ EBI - ARRAY_EXPRESS ]   OSTN [ SEEK ]   OSTN [ MEM ]
Gene Expression Viewer (FireBrowse)OSTN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)344901
GTEX Portal (Tissue expression)OSTN
Human Protein AtlasENSG00000188729-OSTN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61366   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61366  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61366
Splice isoforms : SwissVarP61366
PhosPhoSitePlusP61366
Domains : Interpro (EBI)Osteocrin   
Domain families : Pfam (Sanger)Musclin (PF11037)   
Domain families : Pfam (NCBI)pfam11037   
Conserved Domain (NCBI)OSTN
DMDM Disease mutations344901
Blocks (Seattle)OSTN
SuperfamilyP61366
Human Protein Atlas [tissue]ENSG00000188729-OSTN [tissue]
Peptide AtlasP61366
HPRD17809
IPIIPI00256974   IPI00927723   
Protein Interaction databases
DIP (DOE-UCLA)P61366
IntAct (EBI)P61366
FunCoupENSG00000188729
BioGRIDOSTN
STRING (EMBL)OSTN
ZODIACOSTN
Ontologies - Pathways
QuickGOP61366
Ontology : AmiGOendochondral bone growth  hormone activity  extracellular space  cell surface receptor signaling pathway  positive regulation of cGMP biosynthetic process  negative regulation of osteoblast differentiation  negative regulation of glucose import  negative regulation of dendrite extension  
Ontology : EGO-EBIendochondral bone growth  hormone activity  extracellular space  cell surface receptor signaling pathway  positive regulation of cGMP biosynthetic process  negative regulation of osteoblast differentiation  negative regulation of glucose import  negative regulation of dendrite extension  
NDEx NetworkOSTN
Atlas of Cancer Signalling NetworkOSTN
Wikipedia pathwaysOSTN
Orthology - Evolution
OrthoDB344901
GeneTree (enSembl)ENSG00000188729
Phylogenetic Trees/Animal Genes : TreeFamOSTN
HOVERGENP61366
HOGENOMP61366
Homologs : HomoloGeneOSTN
Homology/Alignments : Family Browser (UCSC)OSTN
Gene fusions - Rearrangements
Tumor Fusion PortalOSTN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOSTN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OSTN
dbVarOSTN
ClinVarOSTN
1000_GenomesOSTN 
Exome Variant ServerOSTN
ExAC (Exome Aggregation Consortium)ENSG00000188729
GNOMAD BrowserENSG00000188729
Genetic variants : HAPMAP344901
Genomic Variants (DGV)OSTN [DGVbeta]
DECIPHEROSTN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOSTN 
Mutations
ICGC Data PortalOSTN 
TCGA Data PortalOSTN 
Broad Tumor PortalOSTN
OASIS PortalOSTN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOSTN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOSTN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OSTN
DgiDB (Drug Gene Interaction Database)OSTN
DoCM (Curated mutations)OSTN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OSTN (select a term)
intoGenOSTN
Cancer3DOSTN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610280   
Orphanet
DisGeNETOSTN
MedgenOSTN
Genetic Testing Registry OSTN
NextProtP61366 [Medical]
TSGene344901
GENETestsOSTN
Target ValidationOSTN
Huge Navigator OSTN [HugePedia]
snp3D : Map Gene to Disease344901
BioCentury BCIQOSTN
ClinGenOSTN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD344901
Chemical/Pharm GKB GenePA134912892
Clinical trialOSTN
Miscellaneous
canSAR (ICR)OSTN (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOSTN
EVEXOSTN
GoPubMedOSTN
iHOPOSTN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:08:41 CET 2017

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