Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

OTOA (otoancorin)

Identity

Alias_namesDFNB22
deafness, autosomal recessive 22
Alias_symbol (synonym)CT108
Other alias
HGNC (Hugo) OTOA
LocusID (NCBI) 146183
Atlas_Id 71572
Location 16p12.2  [Link to chromosome band 16p12]
Location_base_pair Starts at 21684429 and ends at 21760729 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEP112 (17q24.1) / OTOA (16p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OTOA   16378
Cards
Entrez_Gene (NCBI)OTOA  146183  otoancorin
AliasesCT108; DFNB22
GeneCards (Weizmann)OTOA
Ensembl hg19 (Hinxton)ENSG00000155719 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155719 [Gene_View]  chr16:21684429-21760729 [Contig_View]  OTOA [Vega]
ICGC DataPortalENSG00000155719
TCGA cBioPortalOTOA
AceView (NCBI)OTOA
Genatlas (Paris)OTOA
WikiGenes146183
SOURCE (Princeton)OTOA
Genetics Home Reference (NIH)OTOA
Genomic and cartography
GoldenPath hg38 (UCSC)OTOA  -     chr16:21684429-21760729 +  16p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OTOA  -     16p12.2   [Description]    (hg19-Feb_2009)
EnsemblOTOA - 16p12.2 [CytoView hg19]  OTOA - 16p12.2 [CytoView hg38]
Mapping of homologs : NCBIOTOA [Mapview hg19]  OTOA [Mapview hg38]
OMIM607038   607039   
Gene and transcription
Genbank (Entrez)AK093062 AK125840 AK302733 BC038458 BC040551
RefSeq transcript (Entrez)NM_001161683 NM_144672 NM_170664
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OTOA
Cluster EST : UnigeneHs.408336 [ NCBI ]
CGAP (NCI)Hs.408336
Alternative Splicing GalleryENSG00000155719
Gene ExpressionOTOA [ NCBI-GEO ]   OTOA [ EBI - ARRAY_EXPRESS ]   OTOA [ SEEK ]   OTOA [ MEM ]
Gene Expression Viewer (FireBrowse)OTOA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)146183
GTEX Portal (Tissue expression)OTOA
Human Protein AtlasENSG00000155719-OTOA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7RTW8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7RTW8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7RTW8
Splice isoforms : SwissVarQ7RTW8
PhosPhoSitePlusQ7RTW8
Domains : Interpro (EBI)Otoancorin    Stereocilin-rel   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)OTOA
DMDM Disease mutations146183
Blocks (Seattle)OTOA
SuperfamilyQ7RTW8
Human Protein Atlas [tissue]ENSG00000155719-OTOA [tissue]
Peptide AtlasQ7RTW8
HPRD06126
IPIIPI00170800   IPI00186424   IPI00065386   IPI00641079   IPI00657771   IPI00658074   
Protein Interaction databases
DIP (DOE-UCLA)Q7RTW8
IntAct (EBI)Q7RTW8
FunCoupENSG00000155719
BioGRIDOTOA
STRING (EMBL)OTOA
ZODIACOTOA
Ontologies - Pathways
QuickGOQ7RTW8
Ontology : AmiGOextracellular region  proteinaceous extracellular matrix  plasma membrane  C-terminal protein lipidation  cell-matrix adhesion  sensory perception of sound  cell surface  apical plasma membrane  transmission of nerve impulse  anchored component of membrane  
Ontology : EGO-EBIextracellular region  proteinaceous extracellular matrix  plasma membrane  C-terminal protein lipidation  cell-matrix adhesion  sensory perception of sound  cell surface  apical plasma membrane  transmission of nerve impulse  anchored component of membrane  
NDEx NetworkOTOA
Atlas of Cancer Signalling NetworkOTOA
Wikipedia pathwaysOTOA
Orthology - Evolution
OrthoDB146183
GeneTree (enSembl)ENSG00000155719
Phylogenetic Trees/Animal Genes : TreeFamOTOA
HOVERGENQ7RTW8
HOGENOMQ7RTW8
Homologs : HomoloGeneOTOA
Homology/Alignments : Family Browser (UCSC)OTOA
Gene fusions - Rearrangements
Fusion: Tumor Portal OTOA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOTOA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OTOA
dbVarOTOA
ClinVarOTOA
1000_GenomesOTOA 
Exome Variant ServerOTOA
ExAC (Exome Aggregation Consortium)ENSG00000155719
GNOMAD BrowserENSG00000155719
Genetic variants : HAPMAP146183
Genomic Variants (DGV)OTOA [DGVbeta]
DECIPHEROTOA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOTOA 
Mutations
ICGC Data PortalOTOA 
TCGA Data PortalOTOA 
Broad Tumor PortalOTOA
OASIS PortalOTOA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOTOA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOTOA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OTOA
DgiDB (Drug Gene Interaction Database)OTOA
DoCM (Curated mutations)OTOA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OTOA (select a term)
intoGenOTOA
Cancer3DOTOA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607038    607039   
Orphanet12047   
MedgenOTOA
Genetic Testing Registry OTOA
NextProtQ7RTW8 [Medical]
TSGene146183
GENETestsOTOA
Target ValidationOTOA
Huge Navigator OTOA [HugePedia]
snp3D : Map Gene to Disease146183
BioCentury BCIQOTOA
ClinGenOTOA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD146183
Chemical/Pharm GKB GenePA38403
Clinical trialOTOA
Miscellaneous
canSAR (ICR)OTOA (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOTOA
EVEXOTOA
GoPubMedOTOA
iHOPOTOA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:21:27 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.