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OTP (orthopedia homeobox)

Identity

Alias (NCBI)-
HGNC (Hugo) OTP
HGNC Previous nameorthopedia homolog (Drosophila)
LocusID (NCBI) 23440
Atlas_Id 52842
Location 5q14.1  [Link to chromosome band 5q14]
Location_base_pair Starts at 77628712 and ends at 77638713 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OTP (5q14.1) / PACRG (6q26)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)OTP   8518
Cards
Entrez_Gene (NCBI)OTP    orthopedia homeobox
Aliases
GeneCards (Weizmann)OTP
Ensembl hg19 (Hinxton)ENSG00000171540 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171540 [Gene_View]  ENSG00000171540 [Sequence]  chr5:77628712-77638713 [Contig_View]  OTP [Vega]
ICGC DataPortalENSG00000171540
TCGA cBioPortalOTP
AceView (NCBI)OTP
Genatlas (Paris)OTP
SOURCE (Princeton)OTP
Genetics Home Reference (NIH)OTP
Genomic and cartography
GoldenPath hg38 (UCSC)OTP  -     chr5:77628712-77638713 -  5q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OTP  -     5q14.1   [Description]    (hg19-Feb_2009)
GoldenPathOTP - 5q14.1 [CytoView hg19]  OTP - 5q14.1 [CytoView hg38]
ImmunoBaseENSG00000171540
Genome Data Viewer NCBIOTP [Mapview hg19]  
OMIM604529   
Gene and transcription
Genbank (Entrez)BC001800
RefSeq transcript (Entrez)NM_032109
Consensus coding sequences : CCDS (NCBI)OTP
Gene ExpressionOTP [ NCBI-GEO ]   OTP [ EBI - ARRAY_EXPRESS ]   OTP [ SEEK ]   OTP [ MEM ]
Gene Expression Viewer (FireBrowse)OTP [ Firebrowse - Broad ]
GenevisibleExpression of OTP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23440
GTEX Portal (Tissue expression)OTP
Human Protein AtlasENSG00000171540-OTP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5XKR4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5XKR4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5XKR4
PhosPhoSitePlusQ5XKR4
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    OAR (PS50803)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_CS    Homeobox_dom    HTH_motif    OAR_dom   
Domain families : Pfam (Sanger)Homeodomain (PF00046)    OAR (PF03826)   
Domain families : Pfam (NCBI)pfam00046    pfam03826   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)OTP
SuperfamilyQ5XKR4
AlphaFold pdb e-kbQ5XKR4   
Human Protein Atlas [tissue]ENSG00000171540-OTP [tissue]
HPRD05166
Protein Interaction databases
DIP (DOE-UCLA)Q5XKR4
IntAct (EBI)Q5XKR4
BioGRIDOTP
STRING (EMBL)OTP
ZODIACOTP
Ontologies - Pathways
QuickGOQ5XKR4
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  fibrillar center  positive regulation of neuroblast proliferation  DNA binding  protein binding  nucleoplasm  nuclear body  forebrain neuron differentiation  hypothalamus cell differentiation  neurohypophysis development  neuron differentiation  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  fibrillar center  positive regulation of neuroblast proliferation  DNA binding  protein binding  nucleoplasm  nuclear body  forebrain neuron differentiation  hypothalamus cell differentiation  neurohypophysis development  neuron differentiation  
NDEx NetworkOTP
Atlas of Cancer Signalling NetworkOTP
Wikipedia pathwaysOTP
Orthology - Evolution
OrthoDB23440
GeneTree (enSembl)ENSG00000171540
Phylogenetic Trees/Animal Genes : TreeFamOTP
Homologs : HomoloGeneOTP
Homology/Alignments : Family Browser (UCSC)OTP
Gene fusions - Rearrangements
Fusion : QuiverOTP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOTP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OTP
dbVarOTP
ClinVarOTP
MonarchOTP
1000_GenomesOTP 
Exome Variant ServerOTP
GNOMAD BrowserENSG00000171540
Varsome BrowserOTP
ACMGOTP variants
VarityQ5XKR4
Genomic Variants (DGV)OTP [DGVbeta]
DECIPHEROTP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOTP 
Mutations
ICGC Data PortalOTP 
TCGA Data PortalOTP 
Broad Tumor PortalOTP
OASIS PortalOTP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOTP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DOTP
Mutations and Diseases : HGMDOTP
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaOTP
DgiDB (Drug Gene Interaction Database)OTP
DoCM (Curated mutations)OTP
CIViC (Clinical Interpretations of Variants in Cancer)OTP
Cancer3DOTP
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604529   
Orphanet
DisGeNETOTP
MedgenOTP
Genetic Testing Registry OTP
NextProtQ5XKR4 [Medical]
GENETestsOTP
Target ValidationOTP
Huge Navigator OTP [HugePedia]
ClinGenOTP
Clinical trials, drugs, therapy
MyCancerGenomeOTP
Protein Interactions : CTDOTP
Pharm GKB GenePA32844
PharosQ5XKR4
Clinical trialOTP
Miscellaneous
canSAR (ICR)OTP
HarmonizomeOTP
DataMed IndexOTP
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXOTP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:23:57 CEST 2021

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