Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

OTUD7A (OTU deubiquitinase 7A)

Identity

Alias_namesC15orf16
OTUD7
chromosome 15 open reading frame 16
OTU domain containing 7
OTU domain containing 7A
Alias_symbol (synonym)CEZANNE2
Other aliasC16ORF15
HGNC (Hugo) OTUD7A
LocusID (NCBI) 161725
Atlas_Id 53763
Location 15q13.3  [Link to chromosome band 15q13]
Location_base_pair Starts at 31501409 and ends at 31870672 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
OTUD7A (15q13.3) / ASCC3 (6q16.3)TBC1D22A (22q13.31) / OTUD7A (15q13.3)UTY (Yq11.221) / OTUD7A (15q13.3)
TBC1D22A 22q13.31 / OTUD7A 15q13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OTUD7A   20718
Cards
Entrez_Gene (NCBI)OTUD7A  161725  OTU deubiquitinase 7A
AliasesC15orf16; C16ORF15; CEZANNE2; OTUD7
GeneCards (Weizmann)OTUD7A
Ensembl hg19 (Hinxton)ENSG00000169918 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169918 [Gene_View]  chr15:31501409-31870672 [Contig_View]  OTUD7A [Vega]
ICGC DataPortalENSG00000169918
TCGA cBioPortalOTUD7A
AceView (NCBI)OTUD7A
Genatlas (Paris)OTUD7A
WikiGenes161725
SOURCE (Princeton)OTUD7A
Genetics Home Reference (NIH)OTUD7A
Genomic and cartography
GoldenPath hg38 (UCSC)OTUD7A  -     chr15:31501409-31870672 -  15q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OTUD7A  -     15q13.3   [Description]    (hg19-Feb_2009)
EnsemblOTUD7A - 15q13.3 [CytoView hg19]  OTUD7A - 15q13.3 [CytoView hg38]
Mapping of homologs : NCBIOTUD7A [Mapview hg19]  OTUD7A [Mapview hg38]
OMIM612024   
Gene and transcription
Genbank (Entrez)AJ430383 AK126002 AK308630 BC035668 BC172582
RefSeq transcript (Entrez)NM_001329907 NM_130901
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_187660 NW_011332701
Consensus coding sequences : CCDS (NCBI)OTUD7A
Cluster EST : UnigeneHs.668950 [ NCBI ]
CGAP (NCI)Hs.668950
Alternative Splicing GalleryENSG00000169918
Gene ExpressionOTUD7A [ NCBI-GEO ]   OTUD7A [ EBI - ARRAY_EXPRESS ]   OTUD7A [ SEEK ]   OTUD7A [ MEM ]
Gene Expression Viewer (FireBrowse)OTUD7A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)161725
GTEX Portal (Tissue expression)OTUD7A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TE49   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TE49  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TE49
Splice isoforms : SwissVarQ8TE49
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
PhosPhoSitePlusQ8TE49
Domaine pattern : Prosite (Expaxy)OTU (PS50802)    ZF_A20 (PS51036)   
Domains : Interpro (EBI)OTU_dom    Znf_A20   
Domain families : Pfam (Sanger)OTU (PF02338)    zf-A20 (PF01754)   
Domain families : Pfam (NCBI)pfam02338    pfam01754   
Domain families : Smart (EMBL)ZnF_A20 (SM00259)  
Conserved Domain (NCBI)OTUD7A
DMDM Disease mutations161725
Blocks (Seattle)OTUD7A
PDB (SRS)2L2D   
PDB (PDBSum)2L2D   
PDB (IMB)2L2D   
PDB (RSDB)2L2D   
Structural Biology KnowledgeBase2L2D   
SCOP (Structural Classification of Proteins)2L2D   
CATH (Classification of proteins structures)2L2D   
SuperfamilyQ8TE49
Human Protein AtlasENSG00000169918
Peptide AtlasQ8TE49
HPRD12666
IPIIPI00152625   IPI00455137   
Protein Interaction databases
DIP (DOE-UCLA)Q8TE49
IntAct (EBI)Q8TE49
FunCoupENSG00000169918
BioGRIDOTUD7A
STRING (EMBL)OTUD7A
ZODIACOTUD7A
Ontologies - Pathways
QuickGOQ8TE49
Ontology : AmiGODNA binding  thiol-dependent ubiquitin-specific protease activity  nucleus  cytoplasm  cytosol  immune response  zinc ion binding  protein deubiquitination  protein K11-linked deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  negative regulation of I-kappaB kinase/NF-kappaB signaling  regulation of innate immune response  regulation of inflammatory response  K63-linked polyubiquitin binding  protein K63-linked deubiquitination  protein K48-linked deubiquitination  protein deubiquitination involved in ubiquitin-dependent protein catabolic process  
Ontology : EGO-EBIDNA binding  thiol-dependent ubiquitin-specific protease activity  nucleus  cytoplasm  cytosol  immune response  zinc ion binding  protein deubiquitination  protein K11-linked deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  negative regulation of I-kappaB kinase/NF-kappaB signaling  regulation of innate immune response  regulation of inflammatory response  K63-linked polyubiquitin binding  protein K63-linked deubiquitination  protein K48-linked deubiquitination  protein deubiquitination involved in ubiquitin-dependent protein catabolic process  
NDEx NetworkOTUD7A
Atlas of Cancer Signalling NetworkOTUD7A
Wikipedia pathwaysOTUD7A
Orthology - Evolution
OrthoDB161725
GeneTree (enSembl)ENSG00000169918
Phylogenetic Trees/Animal Genes : TreeFamOTUD7A
HOVERGENQ8TE49
HOGENOMQ8TE49
Homologs : HomoloGeneOTUD7A
Homology/Alignments : Family Browser (UCSC)OTUD7A
Gene fusions - Rearrangements
Fusion : MitelmanOTUD7A/ASCC3 [15q13.3/6q16.3]  
Fusion : MitelmanTBC1D22A/OTUD7A [22q13.31/15q13.3]  [t(15;22)(q13;q13)]  
Fusion: TCGATBC1D22A 22q13.31 OTUD7A 15q13.3 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOTUD7A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OTUD7A
dbVarOTUD7A
ClinVarOTUD7A
1000_GenomesOTUD7A 
Exome Variant ServerOTUD7A
ExAC (Exome Aggregation Consortium)OTUD7A (select the gene name)
Genetic variants : HAPMAP161725
Genomic Variants (DGV)OTUD7A [DGVbeta]
DECIPHEROTUD7A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOTUD7A 
Mutations
ICGC Data PortalOTUD7A 
TCGA Data PortalOTUD7A 
Broad Tumor PortalOTUD7A
OASIS PortalOTUD7A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOTUD7A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOTUD7A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OTUD7A
DgiDB (Drug Gene Interaction Database)OTUD7A
DoCM (Curated mutations)OTUD7A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OTUD7A (select a term)
intoGenOTUD7A
Cancer3DOTUD7A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612024   
Orphanet
MedgenOTUD7A
Genetic Testing Registry OTUD7A
NextProtQ8TE49 [Medical]
TSGene161725
GENETestsOTUD7A
Target ValidationOTUD7A
Huge Navigator OTUD7A [HugePedia]
snp3D : Map Gene to Disease161725
BioCentury BCIQOTUD7A
ClinGenOTUD7A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD161725
Chemical/Pharm GKB GenePA134877572
Clinical trialOTUD7A
Miscellaneous
canSAR (ICR)OTUD7A (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOTUD7A
EVEXOTUD7A
GoPubMedOTUD7A
iHOPOTUD7A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:48:09 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.