Atlas of Genetics and Cytogenetics in Oncology and Haematology


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OXSR1 (oxidative stress responsive 1)

Identity

Alias_namesOSR1
oxidative-stress responsive 1
Alias_symbol (synonym)KIAA1101
Other alias
HGNC (Hugo) OXSR1
LocusID (NCBI) 9943
Atlas_Id 41617
Location 3p22.2  [Link to chromosome band 3p22]
Location_base_pair Starts at 38165535 and ends at 38255488 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
OXSR1 (3p22.2) / CALR (19p13.2)OXSR1 (3p22.2) / CTDSPL (3p22.2)OXSR1 (3p22.2) / DAXX (6p21.32)
OXSR1 (3p22.2) / SASH1 (6q24.3)OXSR1 (3p22.2) / SRP72 (4q12)XYLB (3p22.2) / OXSR1 (3p22.2)
OXSR1 3p22.2 / CTDSPL 3p22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OXSR1   8508
Cards
Entrez_Gene (NCBI)OXSR1  9943  oxidative stress responsive 1
AliasesOSR1
GeneCards (Weizmann)OXSR1
Ensembl hg19 (Hinxton)ENSG00000172939 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172939 [Gene_View]  chr3:38165535-38255488 [Contig_View]  OXSR1 [Vega]
ICGC DataPortalENSG00000172939
TCGA cBioPortalOXSR1
AceView (NCBI)OXSR1
Genatlas (Paris)OXSR1
WikiGenes9943
SOURCE (Princeton)OXSR1
Genetics Home Reference (NIH)OXSR1
Genomic and cartography
GoldenPath hg38 (UCSC)OXSR1  -     chr3:38165535-38255488 +  3p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OXSR1  -     3p22.2   [Description]    (hg19-Feb_2009)
EnsemblOXSR1 - 3p22.2 [CytoView hg19]  OXSR1 - 3p22.2 [CytoView hg38]
Mapping of homologs : NCBIOXSR1 [Mapview hg19]  OXSR1 [Mapview hg38]
OMIM604046   
Gene and transcription
Genbank (Entrez)AB017642 AB029024 AF087893 AK309634 BC008726
RefSeq transcript (Entrez)NM_005109
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OXSR1
Cluster EST : UnigeneHs.475970 [ NCBI ]
CGAP (NCI)Hs.475970
Alternative Splicing GalleryENSG00000172939
Gene ExpressionOXSR1 [ NCBI-GEO ]   OXSR1 [ EBI - ARRAY_EXPRESS ]   OXSR1 [ SEEK ]   OXSR1 [ MEM ]
Gene Expression Viewer (FireBrowse)OXSR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9943
GTEX Portal (Tissue expression)OXSR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95747   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95747  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95747
Splice isoforms : SwissVarO95747
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusO95747
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom    Kinase_OSR1/WNK_CCT    Oxsr1    Prot_kinase_dom    Protein_kinase_ATP_BS   
Domain families : Pfam (Sanger)OSR1_C (PF12202)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam12202    pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)OXSR1
DMDM Disease mutations9943
Blocks (Seattle)OXSR1
PDB (SRS)2V3S    2VWI    3DAK   
PDB (PDBSum)2V3S    2VWI    3DAK   
PDB (IMB)2V3S    2VWI    3DAK   
PDB (RSDB)2V3S    2VWI    3DAK   
Structural Biology KnowledgeBase2V3S    2VWI    3DAK   
SCOP (Structural Classification of Proteins)2V3S    2VWI    3DAK   
CATH (Classification of proteins structures)2V3S    2VWI    3DAK   
SuperfamilyO95747
Human Protein AtlasENSG00000172939
Peptide AtlasO95747
HPRD06809
IPIIPI00010080   IPI00924637   IPI00924854   
Protein Interaction databases
DIP (DOE-UCLA)O95747
IntAct (EBI)O95747
FunCoupENSG00000172939
BioGRIDOXSR1
STRING (EMBL)OXSR1
ZODIACOXSR1
Ontologies - Pathways
QuickGOO95747
Ontology : AmiGOmagnesium ion binding  protein serine/threonine kinase activity  signal transducer, downstream of receptor, with serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  cytosol  protein phosphorylation  response to oxidative stress  peptidyl-threonine phosphorylation  signal transduction by protein phosphorylation  intracellular signal transduction  extracellular exosome  cellular hypotonic response  negative regulation of potassium ion transmembrane transporter activity  negative regulation of rubidium ion transmembrane transporter activity  
Ontology : EGO-EBImagnesium ion binding  protein serine/threonine kinase activity  signal transducer, downstream of receptor, with serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  cytosol  protein phosphorylation  response to oxidative stress  peptidyl-threonine phosphorylation  signal transduction by protein phosphorylation  intracellular signal transduction  extracellular exosome  cellular hypotonic response  negative regulation of potassium ion transmembrane transporter activity  negative regulation of rubidium ion transmembrane transporter activity  
NDEx NetworkOXSR1
Atlas of Cancer Signalling NetworkOXSR1
Wikipedia pathwaysOXSR1
Orthology - Evolution
OrthoDB9943
GeneTree (enSembl)ENSG00000172939
Phylogenetic Trees/Animal Genes : TreeFamOXSR1
HOVERGENO95747
HOGENOMO95747
Homologs : HomoloGeneOXSR1
Homology/Alignments : Family Browser (UCSC)OXSR1
Gene fusions - Rearrangements
Fusion : MitelmanOXSR1/CTDSPL [3p22.2/3p22.2]  
Fusion: TCGAOXSR1 3p22.2 CTDSPL 3p22.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOXSR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OXSR1
dbVarOXSR1
ClinVarOXSR1
1000_GenomesOXSR1 
Exome Variant ServerOXSR1
ExAC (Exome Aggregation Consortium)OXSR1 (select the gene name)
Genetic variants : HAPMAP9943
Genomic Variants (DGV)OXSR1 [DGVbeta]
DECIPHEROXSR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOXSR1 
Mutations
ICGC Data PortalOXSR1 
TCGA Data PortalOXSR1 
Broad Tumor PortalOXSR1
OASIS PortalOXSR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOXSR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOXSR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OXSR1
DgiDB (Drug Gene Interaction Database)OXSR1
DoCM (Curated mutations)OXSR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OXSR1 (select a term)
intoGenOXSR1
Cancer3DOXSR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604046   
Orphanet
MedgenOXSR1
Genetic Testing Registry OXSR1
NextProtO95747 [Medical]
TSGene9943
GENETestsOXSR1
Target ValidationOXSR1
Huge Navigator OXSR1 [HugePedia]
snp3D : Map Gene to Disease9943
BioCentury BCIQOXSR1
ClinGenOXSR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9943
Chemical/Pharm GKB GenePA134973207
Clinical trialOXSR1
Miscellaneous
canSAR (ICR)OXSR1 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOXSR1
EVEXOXSR1
GoPubMedOXSR1
iHOPOXSR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:23:27 CEST 2017

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