Atlas of Genetics and Cytogenetics in Oncology and Haematology


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OXT (oxytocin/neurophysin I prepropeptide)

Identity

Alias_namesOT
oxytocin, prepro- (neurophysin I)
oxytocin, prepropeptide
Alias_symbol (synonym)OXT-NPI
OT-NPI
Other alias
HGNC (Hugo) OXT
LocusID (NCBI) 5020
Atlas_Id 45947
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 3071620 and ends at 3072517 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OXT   8528
Cards
Entrez_Gene (NCBI)OXT  5020  oxytocin/neurophysin I prepropeptide
AliasesOT; OT-NPI; OXT-NPI
GeneCards (Weizmann)OXT
Ensembl hg19 (Hinxton)ENSG00000101405 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101405 [Gene_View]  chr20:3071620-3072517 [Contig_View]  OXT [Vega]
ICGC DataPortalENSG00000101405
TCGA cBioPortalOXT
AceView (NCBI)OXT
Genatlas (Paris)OXT
WikiGenes5020
SOURCE (Princeton)OXT
Genetics Home Reference (NIH)OXT
Genomic and cartography
GoldenPath hg38 (UCSC)OXT  -     chr20:3071620-3072517 +  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OXT  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblOXT - 20p13 [CytoView hg19]  OXT - 20p13 [CytoView hg38]
Mapping of homologs : NCBIOXT [Mapview hg19]  OXT [Mapview hg38]
OMIM167050   
Gene and transcription
Genbank (Entrez)AI185553 BC069144 BC101841 BC101843 KJ534910
RefSeq transcript (Entrez)NM_000915
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OXT
Cluster EST : UnigeneHs.113216 [ NCBI ]
CGAP (NCI)Hs.113216
Alternative Splicing GalleryENSG00000101405
Gene ExpressionOXT [ NCBI-GEO ]   OXT [ EBI - ARRAY_EXPRESS ]   OXT [ SEEK ]   OXT [ MEM ]
Gene Expression Viewer (FireBrowse)OXT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5020
GTEX Portal (Tissue expression)OXT
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01178   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01178  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01178
Splice isoforms : SwissVarP01178
PhosPhoSitePlusP01178
Domaine pattern : Prosite (Expaxy)NEUROHYPOPHYS_HORM (PS00264)   
Domains : Interpro (EBI)Neurhyp_horm    Neurohypophysial_hormone_CS   
Domain families : Pfam (Sanger)Hormone_4 (PF00220)    Hormone_5 (PF00184)   
Domain families : Pfam (NCBI)pfam00220    pfam00184   
Domain families : Smart (EMBL)NH (SM00003)  
Domain structure : Prodom (Prabi Lyon)Neurhyp_horm (PD001676)   
Conserved Domain (NCBI)OXT
DMDM Disease mutations5020
Blocks (Seattle)OXT
SuperfamilyP01178
Human Protein AtlasENSG00000101405
Peptide AtlasP01178
HPRD08880
IPIIPI00000144   
Protein Interaction databases
DIP (DOE-UCLA)P01178
IntAct (EBI)P01178
FunCoupENSG00000101405
BioGRIDOXT
STRING (EMBL)OXT
ZODIACOXT
Ontologies - Pathways
QuickGOP01178
Ontology : AmiGOresponse to amphetamine  regulation of heart rate  maternal aggressive behavior  neurohypophyseal hormone activity  extracellular region  extracellular space  signal transduction  positive regulation of cytosolic calcium ion concentration  heart development  female pregnancy  memory  grooming behavior  response to sucrose  positive regulation of norepinephrine secretion  response to activity  secretory granule  sleep  oxytocin receptor binding  response to food  positive regulation of prostaglandin secretion  response to estradiol  response to retinoic acid  response to progesterone  response to prostaglandin E  social behavior  negative regulation of urine volume  positive regulation of renal sodium excretion  response to cocaine  hyperosmotic salinity response  maternal behavior  sperm ejaculation  eating behavior  drinking behavior  terminal bouton  response to peptide hormone  response to ether  negative regulation of blood pressure  positive regulation of blood pressure  positive regulation of ossification  positive regulation of female receptivity  positive regulation of synaptic transmission  response to glucocorticoid  response to cAMP  response to electrical stimulus  regulation of sensory perception of pain  positive regulation of synapse assembly  male mating behavior  positive regulation of penile erection  positive regulation of hindgut contraction  negative regulation of gastric acid secretion  positive regulation of uterine smooth muscle contraction  
Ontology : EGO-EBIresponse to amphetamine  regulation of heart rate  maternal aggressive behavior  neurohypophyseal hormone activity  extracellular region  extracellular space  signal transduction  positive regulation of cytosolic calcium ion concentration  heart development  female pregnancy  memory  grooming behavior  response to sucrose  positive regulation of norepinephrine secretion  response to activity  secretory granule  sleep  oxytocin receptor binding  response to food  positive regulation of prostaglandin secretion  response to estradiol  response to retinoic acid  response to progesterone  response to prostaglandin E  social behavior  negative regulation of urine volume  positive regulation of renal sodium excretion  response to cocaine  hyperosmotic salinity response  maternal behavior  sperm ejaculation  eating behavior  drinking behavior  terminal bouton  response to peptide hormone  response to ether  negative regulation of blood pressure  positive regulation of blood pressure  positive regulation of ossification  positive regulation of female receptivity  positive regulation of synaptic transmission  response to glucocorticoid  response to cAMP  response to electrical stimulus  regulation of sensory perception of pain  positive regulation of synapse assembly  male mating behavior  positive regulation of penile erection  positive regulation of hindgut contraction  negative regulation of gastric acid secretion  positive regulation of uterine smooth muscle contraction  
NDEx NetworkOXT
Atlas of Cancer Signalling NetworkOXT
Wikipedia pathwaysOXT
Orthology - Evolution
OrthoDB5020
GeneTree (enSembl)ENSG00000101405
Phylogenetic Trees/Animal Genes : TreeFamOXT
HOVERGENP01178
HOGENOMP01178
Homologs : HomoloGeneOXT
Homology/Alignments : Family Browser (UCSC)OXT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOXT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OXT
dbVarOXT
ClinVarOXT
1000_GenomesOXT 
Exome Variant ServerOXT
ExAC (Exome Aggregation Consortium)OXT (select the gene name)
Genetic variants : HAPMAP5020
Genomic Variants (DGV)OXT [DGVbeta]
DECIPHEROXT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOXT 
Mutations
ICGC Data PortalOXT 
TCGA Data PortalOXT 
Broad Tumor PortalOXT
OASIS PortalOXT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOXT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOXT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OXT
DgiDB (Drug Gene Interaction Database)OXT
DoCM (Curated mutations)OXT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OXT (select a term)
intoGenOXT
Cancer3DOXT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM167050   
Orphanet
MedgenOXT
Genetic Testing Registry OXT
NextProtP01178 [Medical]
TSGene5020
GENETestsOXT
Target ValidationOXT
Huge Navigator OXT [HugePedia]
snp3D : Map Gene to Disease5020
BioCentury BCIQOXT
ClinGenOXT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5020
Chemical/Pharm GKB GenePA32857
Clinical trialOXT
Miscellaneous
canSAR (ICR)OXT (select the gene name)
Probes
Litterature
PubMed127 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOXT
EVEXOXT
GoPubMedOXT
iHOPOXT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:23:27 CEST 2017

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