Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

OXTR (oxytocin receptor)

Identity

Other aliasOT-R
HGNC (Hugo) OXTR
LocusID (NCBI) 5021
Atlas_Id 49935
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 8792095 and ends at 8811300 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)OXTR   8529
Cards
Entrez_Gene (NCBI)OXTR  5021  oxytocin receptor
AliasesOT-R
GeneCards (Weizmann)OXTR
Ensembl hg19 (Hinxton)ENSG00000180914 [Gene_View]  chr3:8792095-8811300 [Contig_View]  OXTR [Vega]
Ensembl hg38 (Hinxton)ENSG00000180914 [Gene_View]  chr3:8792095-8811300 [Contig_View]  OXTR [Vega]
ICGC DataPortalENSG00000180914
TCGA cBioPortalOXTR
AceView (NCBI)OXTR
Genatlas (Paris)OXTR
WikiGenes5021
SOURCE (Princeton)OXTR
Genetics Home Reference (NIH)OXTR
Genomic and cartography
GoldenPath hg19 (UCSC)OXTR  -     chr3:8792095-8811300 -  3p25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)OXTR  -     3p25.3   [Description]    (hg38-Dec_2013)
EnsemblOXTR - 3p25.3 [CytoView hg19]  OXTR - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBIOXTR [Mapview hg19]  OXTR [Mapview hg38]
OMIM167055   
Gene and transcription
Genbank (Entrez)AK313830 AY389507 BC137443 KJ535048 X64878
RefSeq transcript (Entrez)NM_000916
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_008797 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)OXTR
Cluster EST : UnigeneHs.2820 [ NCBI ]
CGAP (NCI)Hs.2820
Alternative Splicing GalleryENSG00000180914
Gene ExpressionOXTR [ NCBI-GEO ]   OXTR [ EBI - ARRAY_EXPRESS ]   OXTR [ SEEK ]   OXTR [ MEM ]
Gene Expression Viewer (FireBrowse)OXTR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5021
GTEX Portal (Tissue expression)OXTR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30559   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30559  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30559
Splice isoforms : SwissVarP30559
PhosPhoSitePlusP30559
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Oxytocn_rcpt    Vasoprsn_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)OXTR
DMDM Disease mutations5021
Blocks (Seattle)OXTR
SuperfamilyP30559
Human Protein AtlasENSG00000180914
Peptide AtlasP30559
HPRD01328
IPIIPI00026886   IPI00853643   IPI00852765   
Protein Interaction databases
DIP (DOE-UCLA)P30559
IntAct (EBI)P30559
FunCoupENSG00000180914
BioGRIDOXTR
STRING (EMBL)OXTR
ZODIACOXTR
Ontologies - Pathways
QuickGOP30559
Ontology : AmiGOsuckling behavior  response to amphetamine  regulation of systemic arterial blood pressure by vasopressin  oxytocin receptor activity  vasopressin receptor activity  cytosol  plasma membrane  integral component of plasma membrane  microvillus  cell-cell adherens junction  muscle contraction  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  heart development  female pregnancy  lactation  memory  positive regulation of norepinephrine secretion  apical plasma membrane  peptide hormone binding  telencephalon development  sleep  positive regulation of synaptic transmission, GABAergic  response to estradiol  response to progesterone  cellular response to hormone stimulus  response to anoxia  response to cytokine  social behavior  response to cocaine  peptide binding  response to drug  maternal behavior  sperm ejaculation  eating behavior  response to peptide hormone  estrous cycle  positive regulation of blood pressure  positive regulation of vasoconstriction  digestive tract development  positive regulation of synapse assembly  positive regulation of synaptic transmission, glutamatergic  maternal process involved in parturition  positive regulation of penile erection  negative regulation of gastric acid secretion  ERK1 and ERK2 cascade  positive regulation of uterine smooth muscle contraction  response to peptide  
Ontology : EGO-EBIsuckling behavior  response to amphetamine  regulation of systemic arterial blood pressure by vasopressin  oxytocin receptor activity  vasopressin receptor activity  cytosol  plasma membrane  integral component of plasma membrane  microvillus  cell-cell adherens junction  muscle contraction  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  heart development  female pregnancy  lactation  memory  positive regulation of norepinephrine secretion  apical plasma membrane  peptide hormone binding  telencephalon development  sleep  positive regulation of synaptic transmission, GABAergic  response to estradiol  response to progesterone  cellular response to hormone stimulus  response to anoxia  response to cytokine  social behavior  response to cocaine  peptide binding  response to drug  maternal behavior  sperm ejaculation  eating behavior  response to peptide hormone  estrous cycle  positive regulation of blood pressure  positive regulation of vasoconstriction  digestive tract development  positive regulation of synapse assembly  positive regulation of synaptic transmission, glutamatergic  maternal process involved in parturition  positive regulation of penile erection  negative regulation of gastric acid secretion  ERK1 and ERK2 cascade  positive regulation of uterine smooth muscle contraction  response to peptide  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction   
NDEx NetworkOXTR
Atlas of Cancer Signalling NetworkOXTR
Wikipedia pathwaysOXTR
Orthology - Evolution
OrthoDB5021
GeneTree (enSembl)ENSG00000180914
Phylogenetic Trees/Animal Genes : TreeFamOXTR
HOVERGENP30559
HOGENOMP30559
Homologs : HomoloGeneOXTR
Homology/Alignments : Family Browser (UCSC)OXTR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOXTR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OXTR
dbVarOXTR
ClinVarOXTR
1000_GenomesOXTR 
Exome Variant ServerOXTR
ExAC (Exome Aggregation Consortium)OXTR (select the gene name)
Genetic variants : HAPMAP5021
Genomic Variants (DGV)OXTR [DGVbeta]
DECIPHER (Syndromes)3:8792095-8811300  ENSG00000180914
CONAN: Copy Number AnalysisOXTR 
Mutations
ICGC Data PortalOXTR 
TCGA Data PortalOXTR 
Broad Tumor PortalOXTR
OASIS PortalOXTR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOXTR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOXTR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OXTR
DgiDB (Drug Gene Interaction Database)OXTR
DoCM (Curated mutations)OXTR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OXTR (select a term)
intoGenOXTR
Cancer3DOXTR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM167055   
Orphanet
MedgenOXTR
Genetic Testing Registry OXTR
NextProtP30559 [Medical]
TSGene5021
GENETestsOXTR
Huge Navigator OXTR [HugePedia]
snp3D : Map Gene to Disease5021
BioCentury BCIQOXTR
ClinGenOXTR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5021
Chemical/Pharm GKB GenePA32858
Clinical trialOXTR
Miscellaneous
canSAR (ICR)OXTR (select the gene name)
Probes
Litterature
PubMed188 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOXTR
EVEXOXTR
GoPubMedOXTR
iHOPOXTR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:20:06 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.