Atlas of Genetics and Cytogenetics in Oncology and Haematology


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P2RX6 (purinergic receptor P2X, ligand-gated ion channel, 6)

Identity

Other namesP2RXL1
P2X6
P2XM
HGNC (Hugo) P2RX6
LocusID (NCBI) 9127
Location 22q11.21
Location_base_pair Starts at 21369442 and ends at 21382302 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)P2RX6   8538
Cards
Entrez_Gene (NCBI)P2RX6  9127  purinergic receptor P2X, ligand-gated ion channel, 6
GeneCards (Weizmann)P2RX6
Ensembl (Hinxton) [Gene_View]  chr22:21369442-21382302 [Contig_View]  P2RX6 [Vega]
cBioPortalP2RX6
AceView (NCBI)P2RX6
Genatlas (Paris)P2RX6
WikiGenes9127
SOURCE (Princeton)NM_001159554 NM_005446
Genomic and cartography
GoldenPath (UCSC)P2RX6  -  22q11.21   chr22:21369442-21382302 +  22q11.21   [Description]    (hg19-Feb_2009)
EnsemblP2RX6 - 22q11.21 [CytoView]
Mapping of homologs : NCBIP2RX6 [Mapview]
OMIM608077   
Gene and transcription
Genbank (Entrez)AB002058 AF065385 AK309079 BC033488 BC047287
RefSeq transcript (Entrez)NM_001159554 NM_005446
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838740 NW_004929430
Consensus coding sequences : CCDS (NCBI)P2RX6
Cluster EST : UnigeneHs.113275 [ NCBI ]
CGAP (NCI)Hs.113275
Alternative Splicing : Fast-db (Paris)GSHG0019851
Gene ExpressionP2RX6 [ NCBI-GEO ]     P2RX6 [ SEEK ]   P2RX6 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15547 (Uniprot)
NextProtO15547  [Medical]
With graphics : InterProO15547
Splice isoforms : SwissVarO15547 (Swissvar)
Domaine pattern : Prosite (Expaxy)P2X_RECEPTOR (PS01212)   
Domains : Interpro (EBI)P2X6_purnocptor [organisation]   P2X_extracellular_dom [organisation]   P2X_purnocptor [organisation]  
Related proteins : CluSTrO15547
Domain families : Pfam (Sanger)P2X_receptor (PF00864)   
Domain families : Pfam (NCBI)pfam00864   
DMDM Disease mutations9127
Blocks (Seattle)O15547
Peptide AtlasO15547
HPRD08490
Protein Interaction databases
DIP (DOE-UCLA)O15547
IntAct (EBI)O15547
BioGRIDP2RX6
InParanoidO15547
Interologous Interaction database O15547
IntegromeDBP2RX6
STRING (EMBL)P2RX6
Ontologies - Pathways
Ontology : AmiGOpurinergic nucleotide receptor activity  transmembrane signaling receptor activity  extracellular ATP-gated cation channel activity  ATP binding  integral component of nuclear inner membrane  cytoplasm  integral component of plasma membrane  transport  cation transport  muscle contraction  signal transduction  postsynaptic density  channel activity  cell junction  ion transmembrane transport  purinergic nucleotide receptor signaling pathway  purinergic nucleotide receptor signaling pathway  identical protein binding  neuronal cell body  dendritic spine  protein homooligomerization  protein heterooligomerization  transmembrane transport  
Ontology : EGO-EBIpurinergic nucleotide receptor activity  transmembrane signaling receptor activity  extracellular ATP-gated cation channel activity  ATP binding  integral component of nuclear inner membrane  cytoplasm  integral component of plasma membrane  transport  cation transport  muscle contraction  signal transduction  postsynaptic density  channel activity  cell junction  ion transmembrane transport  purinergic nucleotide receptor signaling pathway  purinergic nucleotide receptor signaling pathway  identical protein binding  neuronal cell body  dendritic spine  protein homooligomerization  protein heterooligomerization  transmembrane transport  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction   
Protein Interaction DatabaseP2RX6
Wikipedia pathwaysP2RX6
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)P2RX6
snp3D : Map Gene to Disease9127
SNP (GeneSNP Utah)P2RX6
SNP : HGBaseP2RX6
Genetic variants : HAPMAPP2RX6
Exome VariantP2RX6
1000_GenomesP2RX6 
Somatic Mutations in Cancer : COSMICP2RX6 
CONAN: Copy Number AnalysisP2RX6 
Mutations and Diseases : HGMDP2RX6
Mutations and Diseases : intOGenP2RX6
Genomic VariantsP2RX6  P2RX6 [DGVbeta]
dbVarP2RX6
ClinVarP2RX6
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM608077   
MedgenP2RX6
GENETestsP2RX6
Disease Genetic AssociationP2RX6
Huge Navigator P2RX6 [HugePedia]  P2RX6 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneP2RX6
Homology/Alignments : Family Browser (UCSC)P2RX6
Phylogenetic Trees/Animal Genes : TreeFamP2RX6
Chemical/Protein Interactions : CTD9127
Chemical/Pharm GKB GenePA162398523
Clinical trialP2RX6
Other databases
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
CoreMineP2RX6
iHOPP2RX6
OncoSearchP2RX6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:08:58 CEST 2014

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