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P2RY1 (purinergic receptor P2Y1)

Identity

Alias_namespurinergic receptor P2Y
Alias_symbol (synonym)P2Y1
Other alias
HGNC (Hugo) P2RY1
LocusID (NCBI) 5028
Atlas_Id 45562
Location 3q25.2  [Link to chromosome band 3q25]
Location_base_pair Starts at 152834693 and ends at 152841439 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)P2RY1   8539
LRG (Locus Reference Genomic)LRG_635
Cards
Entrez_Gene (NCBI)P2RY1  5028  purinergic receptor P2Y1
AliasesP2Y1
GeneCards (Weizmann)P2RY1
Ensembl hg19 (Hinxton)ENSG00000169860 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169860 [Gene_View]  chr3:152834693-152841439 [Contig_View]  P2RY1 [Vega]
ICGC DataPortalENSG00000169860
TCGA cBioPortalP2RY1
AceView (NCBI)P2RY1
Genatlas (Paris)P2RY1
WikiGenes5028
SOURCE (Princeton)P2RY1
Genetics Home Reference (NIH)P2RY1
Genomic and cartography
GoldenPath hg38 (UCSC)P2RY1  -     chr3:152834693-152841439 +  3q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)P2RY1  -     3q25.2   [Description]    (hg19-Feb_2009)
EnsemblP2RY1 - 3q25.2 [CytoView hg19]  P2RY1 - 3q25.2 [CytoView hg38]
Mapping of homologs : NCBIP2RY1 [Mapview hg19]  P2RY1 [Mapview hg38]
OMIM601167   
Gene and transcription
Genbank (Entrez)AF018284 AK026659 AK313920 AY136752 BC074784
RefSeq transcript (Entrez)NM_002563
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)P2RY1
Cluster EST : UnigeneHs.654526 [ NCBI ]
CGAP (NCI)Hs.654526
Alternative Splicing GalleryENSG00000169860
Gene ExpressionP2RY1 [ NCBI-GEO ]   P2RY1 [ EBI - ARRAY_EXPRESS ]   P2RY1 [ SEEK ]   P2RY1 [ MEM ]
Gene Expression Viewer (FireBrowse)P2RY1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5028
GTEX Portal (Tissue expression)P2RY1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP47900   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP47900  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP47900
Splice isoforms : SwissVarP47900
PhosPhoSitePlusP47900
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    P2Y1_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)P2RY1
DMDM Disease mutations5028
Blocks (Seattle)P2RY1
PDB (SRS)1Y36    4XNV    4XNW   
PDB (PDBSum)1Y36    4XNV    4XNW   
PDB (IMB)1Y36    4XNV    4XNW   
PDB (RSDB)1Y36    4XNV    4XNW   
Structural Biology KnowledgeBase1Y36    4XNV    4XNW   
SCOP (Structural Classification of Proteins)1Y36    4XNV    4XNW   
CATH (Classification of proteins structures)1Y36    4XNV    4XNW   
SuperfamilyP47900
Human Protein AtlasENSG00000169860
Peptide AtlasP47900
HPRD03103
IPIIPI00026825   
Protein Interaction databases
DIP (DOE-UCLA)P47900
IntAct (EBI)P47900
FunCoupENSG00000169860
BioGRIDP2RY1
STRING (EMBL)P2RY1
ZODIACP2RY1
Ontologies - Pathways
QuickGOP47900
Ontology : AmiGOpositive regulation of protein phosphorylation  adenosine receptor signaling pathway  receptor activity  protein binding  ATP binding  mitochondrion  plasma membrane  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  aging  glial cell migration  response to mechanical stimulus  cell surface  regulation of receptor activity  negative regulation of norepinephrine secretion  postsynaptic density  basolateral plasma membrane  apical plasma membrane  sensory perception of pain  signal transduction involved in regulation of gene expression  platelet activation  dendrite  A1 adenosine receptor binding  positive regulation of inositol trisphosphate biosynthetic process  G-protein coupled purinergic nucleotide receptor signaling pathway  eating behavior  positive regulation of ion transport  ADP binding  cell body  G-protein coupled purinergic nucleotide receptor activity  ATP-activated adenosine receptor activity  ADP-activated adenosine receptor activity  postsynaptic membrane  positive regulation of transcription from RNA polymerase II promoter  positive regulation of hormone secretion  protein heterodimerization activity  negative regulation of binding  positive regulation of penile erection  positive regulation of ERK1 and ERK2 cascade  response to growth factor  cellular response to organic cyclic compound  protein localization to plasma membrane  relaxation of muscle  scaffold protein binding  regulation of blood vessel diameter  
Ontology : EGO-EBIpositive regulation of protein phosphorylation  adenosine receptor signaling pathway  receptor activity  protein binding  ATP binding  mitochondrion  plasma membrane  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  aging  glial cell migration  response to mechanical stimulus  cell surface  regulation of receptor activity  negative regulation of norepinephrine secretion  postsynaptic density  basolateral plasma membrane  apical plasma membrane  sensory perception of pain  signal transduction involved in regulation of gene expression  platelet activation  dendrite  A1 adenosine receptor binding  positive regulation of inositol trisphosphate biosynthetic process  G-protein coupled purinergic nucleotide receptor signaling pathway  eating behavior  positive regulation of ion transport  ADP binding  cell body  G-protein coupled purinergic nucleotide receptor activity  ATP-activated adenosine receptor activity  ADP-activated adenosine receptor activity  postsynaptic membrane  positive regulation of transcription from RNA polymerase II promoter  positive regulation of hormone secretion  protein heterodimerization activity  negative regulation of binding  positive regulation of penile erection  positive regulation of ERK1 and ERK2 cascade  response to growth factor  cellular response to organic cyclic compound  protein localization to plasma membrane  relaxation of muscle  scaffold protein binding  regulation of blood vessel diameter  
Pathways : KEGGRap1 signaling pathway    Neuroactive ligand-receptor interaction   
NDEx NetworkP2RY1
Atlas of Cancer Signalling NetworkP2RY1
Wikipedia pathwaysP2RY1
Orthology - Evolution
OrthoDB5028
GeneTree (enSembl)ENSG00000169860
Phylogenetic Trees/Animal Genes : TreeFamP2RY1
HOVERGENP47900
HOGENOMP47900
Homologs : HomoloGeneP2RY1
Homology/Alignments : Family Browser (UCSC)P2RY1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerP2RY1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)P2RY1
dbVarP2RY1
ClinVarP2RY1
1000_GenomesP2RY1 
Exome Variant ServerP2RY1
ExAC (Exome Aggregation Consortium)P2RY1 (select the gene name)
Genetic variants : HAPMAP5028
Genomic Variants (DGV)P2RY1 [DGVbeta]
DECIPHERP2RY1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisP2RY1 
Mutations
ICGC Data PortalP2RY1 
TCGA Data PortalP2RY1 
Broad Tumor PortalP2RY1
OASIS PortalP2RY1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICP2RY1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDP2RY1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch P2RY1
DgiDB (Drug Gene Interaction Database)P2RY1
DoCM (Curated mutations)P2RY1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)P2RY1 (select a term)
intoGenP2RY1
Cancer3DP2RY1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601167   
Orphanet
MedgenP2RY1
Genetic Testing Registry P2RY1
NextProtP47900 [Medical]
TSGene5028
GENETestsP2RY1
Target ValidationP2RY1
Huge Navigator P2RY1 [HugePedia]
snp3D : Map Gene to Disease5028
BioCentury BCIQP2RY1
ClinGenP2RY1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5028
Chemical/Pharm GKB GenePA32868
Clinical trialP2RY1
Miscellaneous
canSAR (ICR)P2RY1 (select the gene name)
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineP2RY1
EVEXP2RY1
GoPubMedP2RY1
iHOPP2RY1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:23:29 CEST 2017

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