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P2RY14 (purinergic receptor P2Y14)

Identity

Alias_namesGPR105
G protein-coupled receptor 105
purinergic receptor P2Y, G-protein coupled, 14
Alias_symbol (synonym)KIAA0001
Other aliasBPR105
P2Y14
HGNC (Hugo) P2RY14
LocusID (NCBI) 9934
Atlas_Id 71607
Location 3q25.1  [Link to chromosome band 3q25]
Location_base_pair Starts at 151212117 and ends at 151249210 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)P2RY14   16442
Cards
Entrez_Gene (NCBI)P2RY14  9934  purinergic receptor P2Y14
AliasesBPR105; GPR105; P2Y14
GeneCards (Weizmann)P2RY14
Ensembl hg19 (Hinxton)ENSG00000174944 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174944 [Gene_View]  chr3:151212117-151249210 [Contig_View]  P2RY14 [Vega]
ICGC DataPortalENSG00000174944
TCGA cBioPortalP2RY14
AceView (NCBI)P2RY14
Genatlas (Paris)P2RY14
WikiGenes9934
SOURCE (Princeton)P2RY14
Genetics Home Reference (NIH)P2RY14
Genomic and cartography
GoldenPath hg38 (UCSC)P2RY14  -     chr3:151212117-151249210 -  3q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)P2RY14  -     3q25.1   [Description]    (hg19-Feb_2009)
EnsemblP2RY14 - 3q25.1 [CytoView hg19]  P2RY14 - 3q25.1 [CytoView hg38]
Mapping of homologs : NCBIP2RY14 [Mapview hg19]  P2RY14 [Mapview hg38]
OMIM610116   
Gene and transcription
Genbank (Entrez)AK289617 BC034989 CD110153 D13626 EF577400
RefSeq transcript (Entrez)NM_001081455 NM_014879
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)P2RY14
Cluster EST : UnigeneHs.2465 [ NCBI ]
CGAP (NCI)Hs.2465
Alternative Splicing GalleryENSG00000174944
Gene ExpressionP2RY14 [ NCBI-GEO ]   P2RY14 [ EBI - ARRAY_EXPRESS ]   P2RY14 [ SEEK ]   P2RY14 [ MEM ]
Gene Expression Viewer (FireBrowse)P2RY14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9934
GTEX Portal (Tissue expression)P2RY14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15391   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15391  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15391
Splice isoforms : SwissVarQ15391
PhosPhoSitePlusQ15391
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    P2Y14_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)P2RY14
DMDM Disease mutations9934
Blocks (Seattle)P2RY14
PDB (SRS)2B6V   
PDB (PDBSum)2B6V   
PDB (IMB)2B6V   
PDB (RSDB)2B6V   
Structural Biology KnowledgeBase2B6V   
SCOP (Structural Classification of Proteins)2B6V   
CATH (Classification of proteins structures)2B6V   
SuperfamilyQ15391
Human Protein AtlasENSG00000174944
Peptide AtlasQ15391
HPRD08820
IPIIPI00016701   IPI00946709   
Protein Interaction databases
DIP (DOE-UCLA)Q15391
IntAct (EBI)Q15391
FunCoupENSG00000174944
BioGRIDP2RY14
STRING (EMBL)P2RY14
ZODIACP2RY14
Ontologies - Pathways
QuickGOQ15391
Ontology : AmiGOplasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  G-protein coupled purinergic nucleotide receptor signaling pathway  G-protein coupled purinergic nucleotide receptor activity  UDP-activated nucleotide receptor activity  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  G-protein coupled purinergic nucleotide receptor signaling pathway  G-protein coupled purinergic nucleotide receptor activity  UDP-activated nucleotide receptor activity  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkP2RY14
Atlas of Cancer Signalling NetworkP2RY14
Wikipedia pathwaysP2RY14
Orthology - Evolution
OrthoDB9934
GeneTree (enSembl)ENSG00000174944
Phylogenetic Trees/Animal Genes : TreeFamP2RY14
HOVERGENQ15391
HOGENOMQ15391
Homologs : HomoloGeneP2RY14
Homology/Alignments : Family Browser (UCSC)P2RY14
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerP2RY14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)P2RY14
dbVarP2RY14
ClinVarP2RY14
1000_GenomesP2RY14 
Exome Variant ServerP2RY14
ExAC (Exome Aggregation Consortium)P2RY14 (select the gene name)
Genetic variants : HAPMAP9934
Genomic Variants (DGV)P2RY14 [DGVbeta]
DECIPHERP2RY14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisP2RY14 
Mutations
ICGC Data PortalP2RY14 
TCGA Data PortalP2RY14 
Broad Tumor PortalP2RY14
OASIS PortalP2RY14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICP2RY14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDP2RY14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch P2RY14
DgiDB (Drug Gene Interaction Database)P2RY14
DoCM (Curated mutations)P2RY14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)P2RY14 (select a term)
intoGenP2RY14
Cancer3DP2RY14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610116   
Orphanet
MedgenP2RY14
Genetic Testing Registry P2RY14
NextProtQ15391 [Medical]
TSGene9934
GENETestsP2RY14
Target ValidationP2RY14
Huge Navigator P2RY14 [HugePedia]
snp3D : Map Gene to Disease9934
BioCentury BCIQP2RY14
ClinGenP2RY14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9934
Chemical/Pharm GKB GenePA28853
Clinical trialP2RY14
Miscellaneous
canSAR (ICR)P2RY14 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineP2RY14
EVEXP2RY14
GoPubMedP2RY14
iHOPP2RY14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:33:49 CEST 2017

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