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P2RY2 (purinergic receptor P2Y2)

Identity

Alias (NCBI)HP2U
P2RU1
P2U
P2U1
P2UR
P2Y2
P2Y2R
HGNC (Hugo) P2RY2
HGNC Alias symbP2U
HGNC Previous namepurinergic receptor P2Y, G-protein coupled, 2
LocusID (NCBI) 5029
Atlas_Id 41625
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 73218281 and ends at 73242427 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)P2RY2   8541
Cards
Entrez_Gene (NCBI)P2RY2    purinergic receptor P2Y2
AliasesHP2U; P2RU1; P2U; P2U1; 
P2UR; P2Y2; P2Y2R
GeneCards (Weizmann)P2RY2
Ensembl hg19 (Hinxton)ENSG00000175591 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175591 [Gene_View]  ENSG00000175591 [Sequence]  chr11:73218281-73242427 [Contig_View]  P2RY2 [Vega]
ICGC DataPortalENSG00000175591
TCGA cBioPortalP2RY2
AceView (NCBI)P2RY2
Genatlas (Paris)P2RY2
SOURCE (Princeton)P2RY2
Genetics Home Reference (NIH)P2RY2
Genomic and cartography
GoldenPath hg38 (UCSC)P2RY2  -     chr11:73218281-73242427 +  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)P2RY2  -     11q13.4   [Description]    (hg19-Feb_2009)
GoldenPathP2RY2 - 11q13.4 [CytoView hg19]  P2RY2 - 11q13.4 [CytoView hg38]
ImmunoBaseENSG00000175591
Genome Data Viewer NCBIP2RY2 [Mapview hg19]  
OMIM600041   
Gene and transcription
Genbank (Entrez)AK094727 AK313942 AY136753 BC012104 BC028135
RefSeq transcript (Entrez)NM_002564 NM_176071 NM_176072
Consensus coding sequences : CCDS (NCBI)P2RY2
Gene ExpressionP2RY2 [ NCBI-GEO ]   P2RY2 [ EBI - ARRAY_EXPRESS ]   P2RY2 [ SEEK ]   P2RY2 [ MEM ]
Gene Expression Viewer (FireBrowse)P2RY2 [ Firebrowse - Broad ]
GenevisibleExpression of P2RY2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5029
GTEX Portal (Tissue expression)P2RY2
Human Protein AtlasENSG00000175591-P2RY2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41231   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41231  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41231
PhosPhoSitePlusP41231
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    P2Y2_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)P2RY2
PDB (RSDB)1Z8E   
PDB Europe1Z8E   
PDB (PDBSum)1Z8E   
PDB (IMB)1Z8E   
Structural Biology KnowledgeBase1Z8E   
SCOP (Structural Classification of Proteins)1Z8E   
CATH (Classification of proteins structures)1Z8E   
SuperfamilyP41231
AlphaFold pdb e-kbP41231   
Human Protein Atlas [tissue]ENSG00000175591-P2RY2 [tissue]
HPRD02499
Protein Interaction databases
DIP (DOE-UCLA)P41231
IntAct (EBI)P41231
BioGRIDP2RY2
STRING (EMBL)P2RY2
ZODIACP2RY2
Ontologies - Pathways
QuickGOP41231
Ontology : AmiGOprotein binding  plasma membrane  integral component of plasma membrane  cellular ion homeostasis  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  G protein-coupled purinergic nucleotide receptor signaling pathway  signaling receptor activity  G protein-coupled purinergic nucleotide receptor activity  positive regulation of mucus secretion  cellular response to ATP  blood vessel diameter maintenance  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of plasma membrane  cellular ion homeostasis  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  G protein-coupled purinergic nucleotide receptor signaling pathway  signaling receptor activity  G protein-coupled purinergic nucleotide receptor activity  positive regulation of mucus secretion  cellular response to ATP  blood vessel diameter maintenance  
Pathways : BIOCARTAIon Channel and Phorbal Esters Signaling Pathway [Genes]   
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkP2RY2
Atlas of Cancer Signalling NetworkP2RY2
Wikipedia pathwaysP2RY2
Orthology - Evolution
OrthoDB5029
GeneTree (enSembl)ENSG00000175591
Phylogenetic Trees/Animal Genes : TreeFamP2RY2
Homologs : HomoloGeneP2RY2
Homology/Alignments : Family Browser (UCSC)P2RY2
Gene fusions - Rearrangements
Fusion : QuiverP2RY2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerP2RY2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)P2RY2
dbVarP2RY2
ClinVarP2RY2
MonarchP2RY2
1000_GenomesP2RY2 
Exome Variant ServerP2RY2
GNOMAD BrowserENSG00000175591
Varsome BrowserP2RY2
ACMGP2RY2 variants
VarityP41231
Genomic Variants (DGV)P2RY2 [DGVbeta]
DECIPHERP2RY2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisP2RY2 
Mutations
ICGC Data PortalP2RY2 
TCGA Data PortalP2RY2 
Broad Tumor PortalP2RY2
OASIS PortalP2RY2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICP2RY2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DP2RY2
Mutations and Diseases : HGMDP2RY2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaP2RY2
DgiDB (Drug Gene Interaction Database)P2RY2
DoCM (Curated mutations)P2RY2
CIViC (Clinical Interpretations of Variants in Cancer)P2RY2
Cancer3DP2RY2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600041   
Orphanet
DisGeNETP2RY2
MedgenP2RY2
Genetic Testing Registry P2RY2
NextProtP41231 [Medical]
GENETestsP2RY2
Target ValidationP2RY2
Huge Navigator P2RY2 [HugePedia]
ClinGenP2RY2
Clinical trials, drugs, therapy
MyCancerGenomeP2RY2
Protein Interactions : CTDP2RY2
Pharm GKB GenePA32870
PharosP41231
Clinical trialP2RY2
Miscellaneous
canSAR (ICR)P2RY2
HarmonizomeP2RY2
DataMed IndexP2RY2
Probes
Litterature
PubMed131 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXP2RY2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:24:04 CEST 2021

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