Atlas of Genetics and Cytogenetics in Oncology and Haematology


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P2RY2 (purinergic receptor P2Y2)

Identity

Alias_namespurinergic receptor P2Y
Alias_symbol (synonym)P2U
Other aliasHP2U
P2RU1
P2U1
P2UR
P2Y2
P2Y2R
HGNC (Hugo) P2RY2
LocusID (NCBI) 5029
Atlas_Id 41625
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 73218298 and ends at 73242427 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)P2RY2   8541
Cards
Entrez_Gene (NCBI)P2RY2  5029  purinergic receptor P2Y2
AliasesHP2U; P2RU1; P2U; P2U1; 
P2UR; P2Y2; P2Y2R
GeneCards (Weizmann)P2RY2
Ensembl hg19 (Hinxton)ENSG00000175591 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175591 [Gene_View]  ENSG00000175591 [Sequence]  chr11:73218298-73242427 [Contig_View]  P2RY2 [Vega]
ICGC DataPortalENSG00000175591
TCGA cBioPortalP2RY2
AceView (NCBI)P2RY2
Genatlas (Paris)P2RY2
WikiGenes5029
SOURCE (Princeton)P2RY2
Genetics Home Reference (NIH)P2RY2
Genomic and cartography
GoldenPath hg38 (UCSC)P2RY2  -     chr11:73218298-73242427 +  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)P2RY2  -     11q13.4   [Description]    (hg19-Feb_2009)
EnsemblP2RY2 - 11q13.4 [CytoView hg19]  P2RY2 - 11q13.4 [CytoView hg38]
Mapping of homologs : NCBIP2RY2 [Mapview hg19]  P2RY2 [Mapview hg38]
OMIM600041   
Gene and transcription
Genbank (Entrez)AK094727 AK313942 AY136753 BC012104 BC028135
RefSeq transcript (Entrez)NM_002564 NM_176071 NM_176072
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)P2RY2
Cluster EST : UnigeneHs.572077 [ NCBI ]
CGAP (NCI)Hs.572077
Alternative Splicing GalleryENSG00000175591
Gene ExpressionP2RY2 [ NCBI-GEO ]   P2RY2 [ EBI - ARRAY_EXPRESS ]   P2RY2 [ SEEK ]   P2RY2 [ MEM ]
Gene Expression Viewer (FireBrowse)P2RY2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5029
GTEX Portal (Tissue expression)P2RY2
Human Protein AtlasENSG00000175591-P2RY2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41231   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41231  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41231
Splice isoforms : SwissVarP41231
PhosPhoSitePlusP41231
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    P2Y2_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)P2RY2
DMDM Disease mutations5029
Blocks (Seattle)P2RY2
PDB (SRS)1Z8E   
PDB (PDBSum)1Z8E   
PDB (IMB)1Z8E   
PDB (RSDB)1Z8E   
Structural Biology KnowledgeBase1Z8E   
SCOP (Structural Classification of Proteins)1Z8E   
CATH (Classification of proteins structures)1Z8E   
SuperfamilyP41231
Human Protein Atlas [tissue]ENSG00000175591-P2RY2 [tissue]
Peptide AtlasP41231
HPRD02499
IPIIPI00298653   
Protein Interaction databases
DIP (DOE-UCLA)P41231
IntAct (EBI)P41231
FunCoupENSG00000175591
BioGRIDP2RY2
STRING (EMBL)P2RY2
ZODIACP2RY2
Ontologies - Pathways
QuickGOP41231
Ontology : AmiGOplasma membrane  integral component of plasma membrane  cellular ion homeostasis  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  G protein-coupled purinergic nucleotide receptor signaling pathway  signaling receptor activity  G protein-coupled purinergic nucleotide receptor activity  positive regulation of mucus secretion  cellular response to ATP  regulation of blood vessel diameter  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  cellular ion homeostasis  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  G protein-coupled purinergic nucleotide receptor signaling pathway  signaling receptor activity  G protein-coupled purinergic nucleotide receptor activity  positive regulation of mucus secretion  cellular response to ATP  regulation of blood vessel diameter  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkP2RY2
Atlas of Cancer Signalling NetworkP2RY2
Wikipedia pathwaysP2RY2
Orthology - Evolution
OrthoDB5029
GeneTree (enSembl)ENSG00000175591
Phylogenetic Trees/Animal Genes : TreeFamP2RY2
HOVERGENP41231
HOGENOMP41231
Homologs : HomoloGeneP2RY2
Homology/Alignments : Family Browser (UCSC)P2RY2
Gene fusions - Rearrangements
Fusion : QuiverP2RY2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerP2RY2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)P2RY2
dbVarP2RY2
ClinVarP2RY2
1000_GenomesP2RY2 
Exome Variant ServerP2RY2
ExAC (Exome Aggregation Consortium)ENSG00000175591
GNOMAD BrowserENSG00000175591
Varsome BrowserP2RY2
Genetic variants : HAPMAP5029
Genomic Variants (DGV)P2RY2 [DGVbeta]
DECIPHERP2RY2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisP2RY2 
Mutations
ICGC Data PortalP2RY2 
TCGA Data PortalP2RY2 
Broad Tumor PortalP2RY2
OASIS PortalP2RY2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICP2RY2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDP2RY2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch P2RY2
DgiDB (Drug Gene Interaction Database)P2RY2
DoCM (Curated mutations)P2RY2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)P2RY2 (select a term)
intoGenP2RY2
Cancer3DP2RY2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600041   
Orphanet
DisGeNETP2RY2
MedgenP2RY2
Genetic Testing Registry P2RY2
NextProtP41231 [Medical]
TSGene5029
GENETestsP2RY2
Target ValidationP2RY2
Huge Navigator P2RY2 [HugePedia]
snp3D : Map Gene to Disease5029
BioCentury BCIQP2RY2
ClinGenP2RY2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5029
Chemical/Pharm GKB GenePA32870
Clinical trialP2RY2
Miscellaneous
canSAR (ICR)P2RY2 (select the gene name)
Probes
Litterature
PubMed120 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineP2RY2
EVEXP2RY2
GoPubMedP2RY2
iHOPP2RY2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:28:11 CET 2018

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