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P2RY4 (pyrimidinergic receptor P2Y4)

Identity

Alias_namespyrimidinergic receptor P2Y, G-protein coupled, 4
Alias_symbol (synonym)NRU
P2Y4
UNR
P2P
Other alias
HGNC (Hugo) P2RY4
LocusID (NCBI) 5030
Atlas_Id 71608
Location Xq13.1  [Link to chromosome band Xq13]
Location_base_pair Starts at 70258166 and ends at 70259804 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)P2RY4   8542
Cards
Entrez_Gene (NCBI)P2RY4  5030  pyrimidinergic receptor P2Y4
AliasesNRU; P2P; P2Y4; UNR
GeneCards (Weizmann)P2RY4
Ensembl hg19 (Hinxton)ENSG00000186912 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186912 [Gene_View]  chrX:70258166-70259804 [Contig_View]  P2RY4 [Vega]
ICGC DataPortalENSG00000186912
TCGA cBioPortalP2RY4
AceView (NCBI)P2RY4
Genatlas (Paris)P2RY4
WikiGenes5030
SOURCE (Princeton)P2RY4
Genetics Home Reference (NIH)P2RY4
Genomic and cartography
GoldenPath hg38 (UCSC)P2RY4  -     chrX:70258166-70259804 -  Xq13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)P2RY4  -     Xq13.1   [Description]    (hg19-Feb_2009)
EnsemblP2RY4 - Xq13.1 [CytoView hg19]  P2RY4 - Xq13.1 [CytoView hg38]
Mapping of homologs : NCBIP2RY4 [Mapview hg19]  P2RY4 [Mapview hg38]
OMIM300038   
Gene and transcription
Genbank (Entrez)BC095503 BC096067 BC096068 BC096069 BC096070
RefSeq transcript (Entrez)NM_002565
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)P2RY4
Cluster EST : UnigeneHs.673854 [ NCBI ]
CGAP (NCI)Hs.673854
Alternative Splicing GalleryENSG00000186912
Gene ExpressionP2RY4 [ NCBI-GEO ]   P2RY4 [ EBI - ARRAY_EXPRESS ]   P2RY4 [ SEEK ]   P2RY4 [ MEM ]
Gene Expression Viewer (FireBrowse)P2RY4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5030
GTEX Portal (Tissue expression)P2RY4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51582   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51582  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51582
Splice isoforms : SwissVarP51582
PhosPhoSitePlusP51582
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    P2Y4   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)P2RY4
DMDM Disease mutations5030
Blocks (Seattle)P2RY4
PDB (SRS)2B6Q   
PDB (PDBSum)2B6Q   
PDB (IMB)2B6Q   
PDB (RSDB)2B6Q   
Structural Biology KnowledgeBase2B6Q   
SCOP (Structural Classification of Proteins)2B6Q   
CATH (Classification of proteins structures)2B6Q   
SuperfamilyP51582
Human Protein AtlasENSG00000186912
Peptide AtlasP51582
HPRD02075
IPIIPI00019403   
Protein Interaction databases
DIP (DOE-UCLA)P51582
IntAct (EBI)P51582
FunCoupENSG00000186912
BioGRIDP2RY4
STRING (EMBL)P2RY4
ZODIACP2RY4
Ontologies - Pathways
QuickGOP51582
Ontology : AmiGOATP binding  plasma membrane  integral component of plasma membrane  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  uridine nucleotide receptor activity  basolateral plasma membrane  apical plasma membrane  transepithelial chloride transport  G-protein coupled purinergic nucleotide receptor signaling pathway  G-protein coupled purinergic nucleotide receptor activity  UTP-activated nucleotide receptor activity  cellular response to prostaglandin E stimulus  
Ontology : EGO-EBIATP binding  plasma membrane  integral component of plasma membrane  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  uridine nucleotide receptor activity  basolateral plasma membrane  apical plasma membrane  transepithelial chloride transport  G-protein coupled purinergic nucleotide receptor signaling pathway  G-protein coupled purinergic nucleotide receptor activity  UTP-activated nucleotide receptor activity  cellular response to prostaglandin E stimulus  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkP2RY4
Atlas of Cancer Signalling NetworkP2RY4
Wikipedia pathwaysP2RY4
Orthology - Evolution
OrthoDB5030
GeneTree (enSembl)ENSG00000186912
Phylogenetic Trees/Animal Genes : TreeFamP2RY4
HOVERGENP51582
HOGENOMP51582
Homologs : HomoloGeneP2RY4
Homology/Alignments : Family Browser (UCSC)P2RY4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerP2RY4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)P2RY4
dbVarP2RY4
ClinVarP2RY4
1000_GenomesP2RY4 
Exome Variant ServerP2RY4
ExAC (Exome Aggregation Consortium)P2RY4 (select the gene name)
Genetic variants : HAPMAP5030
Genomic Variants (DGV)P2RY4 [DGVbeta]
DECIPHERP2RY4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisP2RY4 
Mutations
ICGC Data PortalP2RY4 
TCGA Data PortalP2RY4 
Broad Tumor PortalP2RY4
OASIS PortalP2RY4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICP2RY4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDP2RY4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch P2RY4
DgiDB (Drug Gene Interaction Database)P2RY4
DoCM (Curated mutations)P2RY4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)P2RY4 (select a term)
intoGenP2RY4
Cancer3DP2RY4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300038   
Orphanet
MedgenP2RY4
Genetic Testing Registry P2RY4
NextProtP51582 [Medical]
TSGene5030
GENETestsP2RY4
Target ValidationP2RY4
Huge Navigator P2RY4 [HugePedia]
snp3D : Map Gene to Disease5030
BioCentury BCIQP2RY4
ClinGenP2RY4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5030
Chemical/Pharm GKB GenePA32871
Clinical trialP2RY4
Miscellaneous
canSAR (ICR)P2RY4 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineP2RY4
EVEXP2RY4
GoPubMedP2RY4
iHOPP2RY4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:35:21 CEST 2017

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