| Nomenclature |
HGNC (Hugo) | P2RY6 8543 |
| Cards |
Entrez_Gene (NCBI) | P2RY6 pyrimidinergic receptor P2Y6 |
Aliases | P2Y6 |
GeneCards (Weizmann) | P2RY6 |
Ensembl hg19 (Hinxton) | ENSG00000171631 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000171631 [Gene_View]  ENSG00000171631 [Sequence] chr11:73269894-73298625 [Contig_View] P2RY6 [Vega] |
ICGC DataPortal | ENSG00000171631 |
TCGA cBioPortal | P2RY6 |
AceView (NCBI) | P2RY6 |
Genatlas (Paris) | P2RY6 |
SOURCE (Princeton) | P2RY6 |
Genetics Home Reference (NIH) | P2RY6 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | P2RY6 - chr11:73269894-73298625 + 11q13.4 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | P2RY6 - 11q13.4 [Description] (hg19-Feb_2009) |
GoldenPath | P2RY6 - 11q13.4 [CytoView hg19] P2RY6 - 11q13.4 [CytoView hg38] |
ImmunoBase | ENSG00000171631 |
genome Data Viewer NCBI | P2RY6 [Mapview hg19] |
OMIM | 602451 |
| Gene and transcription |
Genbank (Entrez) | AF007891 AF007892 AF007893 AF218005 AF498920 |
RefSeq transcript (Entrez) | NM_001277204 NM_001277205 NM_001277206 NM_001277207 NM_001277208 NM_004154 NM_176796 NM_176797 NM_176798 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | P2RY6 |
Alternative Splicing Gallery | ENSG00000171631 |
Gene Expression | P2RY6 [ NCBI-GEO ] P2RY6 [ EBI - ARRAY_EXPRESS ]
P2RY6 [ SEEK ] P2RY6 [ MEM ] |
Gene Expression Viewer (FireBrowse) | P2RY6 [ Firebrowse - Broad ] |
Genevisible | Expression of P2RY6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 5031 |
GTEX Portal (Tissue expression) | P2RY6 |
Human Protein Atlas | ENSG00000171631-P2RY6 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q15077 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q15077 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q15077 |
Splice isoforms : SwissVar | Q15077 |
PhosPhoSitePlus | Q15077 |
Domaine pattern : Prosite (Expaxy) | G_PROTEIN_RECEP_F1_2 (PS50262) |
Domains : Interpro (EBI) | GPCR_Rhodpsn GPCR_Rhodpsn_7TM P2Y6_rcpt |
Domain families : Pfam (Sanger) | 7tm_1 (PF00001) |
Domain families : Pfam (NCBI) | pfam00001 |
Conserved Domain (NCBI) | P2RY6 |
Blocks (Seattle) | P2RY6 |
PDB (RSDB) | 2B6R |
PDB Europe | 2B6R |
PDB (PDBSum) | 2B6R |
PDB (IMB) | 2B6R |
Structural Biology KnowledgeBase | 2B6R |
SCOP (Structural Classification of Proteins) | 2B6R |
CATH (Classification of proteins structures) | 2B6R |
Superfamily | Q15077 |
Human Protein Atlas [tissue] | ENSG00000171631-P2RY6 [tissue] |
Peptide Atlas | Q15077 |
HPRD | 03906 |
IPI | IPI00014315 IPI01013029 IPI01011114 IPI01011769 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q15077 |
IntAct (EBI) | Q15077 |
BioGRID | P2RY6 |
STRING (EMBL) | P2RY6 |
ZODIAC | P2RY6 |
| Ontologies - Pathways |
QuickGO | Q15077 |
Ontology : AmiGO | ADP receptor activity G protein-coupled receptor activity protein binding plasma membrane plasma membrane integral component of plasma membrane phagocytosis G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway activation of phospholipase C activity positive regulation of smooth muscle cell migration basolateral plasma membrane apical plasma membrane transepithelial chloride transport positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity positive regulation of inositol trisphosphate biosynthetic process positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor signaling pathway UDP-activated nucleotide receptor activity UTP-activated nucleotide receptor activity positive regulation of ERK1 and ERK2 cascade cellular response to prostaglandin E stimulus cellular response to purine-containing compound positive regulation of vascular smooth muscle cell proliferation cellular response to pyrimidine ribonucleotide cellular response to pyrimidine ribonucleotide |
Ontology : EGO-EBI | ADP receptor activity G protein-coupled receptor activity protein binding plasma membrane plasma membrane integral component of plasma membrane phagocytosis G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway activation of phospholipase C activity positive regulation of smooth muscle cell migration basolateral plasma membrane apical plasma membrane transepithelial chloride transport positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity positive regulation of inositol trisphosphate biosynthetic process positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor signaling pathway UDP-activated nucleotide receptor activity UTP-activated nucleotide receptor activity positive regulation of ERK1 and ERK2 cascade cellular response to prostaglandin E stimulus cellular response to purine-containing compound positive regulation of vascular smooth muscle cell proliferation cellular response to pyrimidine ribonucleotide cellular response to pyrimidine ribonucleotide |
Pathways : KEGG | Neuroactive ligand-receptor interaction |
NDEx Network | P2RY6 |
Atlas of Cancer Signalling Network | P2RY6 |
Wikipedia pathways | P2RY6 |
| Orthology - Evolution |
OrthoDB | 5031 |
GeneTree (enSembl) | ENSG00000171631 |
Phylogenetic Trees/Animal Genes : TreeFam | P2RY6 |
HOGENOM | Q15077 |
Homologs : HomoloGene | P2RY6 |
Homology/Alignments : Family Browser (UCSC) | P2RY6 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | C2CD3/P2RY6 [11q13.4/11q13.4]   |
Fusion Portal | C2CD3 11q13.4 P2RY6 11q13.4 BRCA |
Fusion : Quiver | P2RY6 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | P2RY6 [hg38] |
dbVar | P2RY6 |
ClinVar | P2RY6 |
Monarch | P2RY6 |
1000_Genomes | P2RY6 |
Exome Variant Server | P2RY6 |
GNOMAD Browser | ENSG00000171631 |
Varsome Browser | P2RY6 |
Genomic Variants (DGV) | P2RY6 [DGVbeta] |
DECIPHER | P2RY6 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | P2RY6 |
| Mutations |
ICGC Data Portal | P2RY6 |
TCGA Data Portal | P2RY6 |
Broad Tumor Portal | P2RY6 |
OASIS Portal | P2RY6 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | P2RY6 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | P2RY6 |
Mutations and Diseases : HGMD | P2RY6 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search P2RY6 |
DgiDB (Drug Gene Interaction Database) | P2RY6 |
DoCM (Curated mutations) | P2RY6 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | P2RY6 (select a term) |
intoGen | P2RY6 |
Cancer3D | P2RY6(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
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OMIM | 602451 |
Orphanet | |
DisGeNET | P2RY6 |
Medgen | P2RY6 |
Genetic Testing Registry | P2RY6
|
NextProt | Q15077 [Medical] |
GENETests | P2RY6 |
Target Validation | P2RY6 |
Huge Navigator |
P2RY6 [HugePedia] |
ClinGen | P2RY6 |
| Clinical trials, drugs, therapy |
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MyCancerGenome | P2RY6 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA32872 |
Pharos | Q15077 |
Clinical trial | P2RY6 |
| Miscellaneous |
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canSAR (ICR) | P2RY6 (select the gene name) |
Harmonizome | P2RY6 |
DataMed Index | P2RY6 |
| Probes |
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| Litterature |
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PubMed | 52 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | P2RY6 |