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PAAF1 (proteasomal ATPase associated factor 1)

Identity

Alias (NCBI)PAAF
Rpn14
WDR71
HGNC (Hugo) PAAF1
HGNC Alias symbFLJ11848
Rpn14
HGNC Previous nameWDR71
HGNC Previous nameWD repeat domain 71
LocusID (NCBI) 80227
Atlas_Id 52700
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 73876999 and ends at 73931112 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PAAF1 (11q13.4) / PAAF1 (11q13.4)RNFT1 (17q23.1) / PAAF1 (11q13.4)RPS6KB2 (11q13.2) / PAAF1 (11q13.4)
RNFT1 17q23.1 / PAAF1 11q13.4RPS6KB2 11q13.2 / PAAF1 11q13.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PAAF1   25687
Cards
Entrez_Gene (NCBI)PAAF1    proteasomal ATPase associated factor 1
AliasesPAAF; Rpn14; WDR71
GeneCards (Weizmann)PAAF1
Ensembl hg19 (Hinxton)ENSG00000175575 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175575 [Gene_View]  ENSG00000175575 [Sequence]  chr11:73876999-73931112 [Contig_View]  PAAF1 [Vega]
ICGC DataPortalENSG00000175575
TCGA cBioPortalPAAF1
AceView (NCBI)PAAF1
Genatlas (Paris)PAAF1
SOURCE (Princeton)PAAF1
Genetics Home Reference (NIH)PAAF1
Genomic and cartography
GoldenPath hg38 (UCSC)PAAF1  -     chr11:73876999-73931112 +  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAAF1  -     11q13.4   [Description]    (hg19-Feb_2009)
GoldenPathPAAF1 - 11q13.4 [CytoView hg19]  PAAF1 - 11q13.4 [CytoView hg38]
ImmunoBaseENSG00000175575
Genome Data Viewer NCBIPAAF1 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AF087895 AK021910 AK222501 AK225520 AK298258
RefSeq transcript (Entrez)NM_001267803 NM_001267804 NM_001267805 NM_001267806 NM_001363556 NM_025155
Consensus coding sequences : CCDS (NCBI)PAAF1
Gene ExpressionPAAF1 [ NCBI-GEO ]   PAAF1 [ EBI - ARRAY_EXPRESS ]   PAAF1 [ SEEK ]   PAAF1 [ MEM ]
Gene Expression Viewer (FireBrowse)PAAF1 [ Firebrowse - Broad ]
GenevisibleExpression of PAAF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80227
GTEX Portal (Tissue expression)PAAF1
Human Protein AtlasENSG00000175575-PAAF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRP4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRP4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRP4
PhosPhoSitePlusQ9BRP4
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)PAAF1
SuperfamilyQ9BRP4
AlphaFold pdb e-kbQ9BRP4   
Human Protein Atlas [tissue]ENSG00000175575-PAAF1 [tissue]
HPRD07761
Protein Interaction databases
DIP (DOE-UCLA)Q9BRP4
IntAct (EBI)Q9BRP4
BioGRIDPAAF1
STRING (EMBL)PAAF1
ZODIACPAAF1
Ontologies - Pathways
QuickGOQ9BRP4
Ontology : AmiGOproteasome complex  protein binding  
Ontology : EGO-EBIproteasome complex  protein binding  
NDEx NetworkPAAF1
Atlas of Cancer Signalling NetworkPAAF1
Wikipedia pathwaysPAAF1
Orthology - Evolution
OrthoDB80227
GeneTree (enSembl)ENSG00000175575
Phylogenetic Trees/Animal Genes : TreeFamPAAF1
Homologs : HomoloGenePAAF1
Homology/Alignments : Family Browser (UCSC)PAAF1
Gene fusions - Rearrangements
Fusion : MitelmanRNFT1/PAAF1 [17q23.1/11q13.4]  
Fusion : MitelmanRPS6KB2/PAAF1 [11q13.2/11q13.4]  
Fusion : QuiverPAAF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAAF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAAF1
dbVarPAAF1
ClinVarPAAF1
MonarchPAAF1
1000_GenomesPAAF1 
Exome Variant ServerPAAF1
GNOMAD BrowserENSG00000175575
Varsome BrowserPAAF1
ACMGPAAF1 variants
VarityQ9BRP4
Genomic Variants (DGV)PAAF1 [DGVbeta]
DECIPHERPAAF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAAF1 
Mutations
ICGC Data PortalPAAF1 
TCGA Data PortalPAAF1 
Broad Tumor PortalPAAF1
OASIS PortalPAAF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAAF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPAAF1
Mutations and Diseases : HGMDPAAF1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPAAF1
DgiDB (Drug Gene Interaction Database)PAAF1
DoCM (Curated mutations)PAAF1
CIViC (Clinical Interpretations of Variants in Cancer)PAAF1
Cancer3DPAAF1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPAAF1
MedgenPAAF1
Genetic Testing Registry PAAF1
NextProtQ9BRP4 [Medical]
GENETestsPAAF1
Target ValidationPAAF1
Huge Navigator PAAF1 [HugePedia]
ClinGenPAAF1
Clinical trials, drugs, therapy
MyCancerGenomePAAF1
Protein Interactions : CTDPAAF1
Pharm GKB GenePA162398551
PharosQ9BRP4
Clinical trialPAAF1
Miscellaneous
canSAR (ICR)PAAF1
HarmonizomePAAF1
DataMed IndexPAAF1
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPAAF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:24:07 CEST 2021

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