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PABPC1L (poly(A) binding protein cytoplasmic 1 like)

Identity

Alias_namesC20orf119
chromosome 20 open reading frame 119
poly(A) binding protein, cytoplasmic 1-like
Alias_symbol (synonym)dJ1069P2.3
PABPC1L1
ePAB
Other aliasEPAB
HGNC (Hugo) PABPC1L
LocusID (NCBI) 80336
Atlas_Id 71612
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 44910060 and ends at 44939317 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GAS5 (1q25.1) / PABPC1L (20q13.12)MIA3 (1q41) / PABPC1L (20q13.12)PABPC1L (20q13.12) / CPNE7 (16q24.3)
PABPC1L (20q13.12) / LUM (12q21.33)PABPC1L (20q13.12) / MRPL39 (21q21.3)PABPC1L (20q13.12) / YWHAB (20q13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PABPC1L   15797
Cards
Entrez_Gene (NCBI)PABPC1L  80336  poly(A) binding protein cytoplasmic 1 like
AliasesC20orf119; EPAB; PABPC1L1; dJ1069P2.3
GeneCards (Weizmann)PABPC1L
Ensembl hg19 (Hinxton)ENSG00000101104 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101104 [Gene_View]  chr20:44910060-44939317 [Contig_View]  PABPC1L [Vega]
ICGC DataPortalENSG00000101104
TCGA cBioPortalPABPC1L
AceView (NCBI)PABPC1L
Genatlas (Paris)PABPC1L
WikiGenes80336
SOURCE (Princeton)PABPC1L
Genetics Home Reference (NIH)PABPC1L
Genomic and cartography
GoldenPath hg38 (UCSC)PABPC1L  -     chr20:44910060-44939317 +  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PABPC1L  -     20q13.12   [Description]    (hg19-Feb_2009)
EnsemblPABPC1L - 20q13.12 [CytoView hg19]  PABPC1L - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIPABPC1L [Mapview hg19]  PABPC1L [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI597906 AK021902 AK026760 AK055371 AK124047
RefSeq transcript (Entrez)NM_001124756
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PABPC1L
Cluster EST : UnigeneHs.641481 [ NCBI ]
CGAP (NCI)Hs.641481
Alternative Splicing GalleryENSG00000101104
Gene ExpressionPABPC1L [ NCBI-GEO ]   PABPC1L [ EBI - ARRAY_EXPRESS ]   PABPC1L [ SEEK ]   PABPC1L [ MEM ]
Gene Expression Viewer (FireBrowse)PABPC1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80336
GTEX Portal (Tissue expression)PABPC1L
Human Protein AtlasENSG00000101104-PABPC1L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ4VXU2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ4VXU2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ4VXU2
Splice isoforms : SwissVarQ4VXU2
PhosPhoSitePlusQ4VXU2
Domaine pattern : Prosite (Expaxy)PABC (PS51309)    RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    PABP_1234    PABP_HYD    RRM_dom    RRM_dom_euk   
Domain families : Pfam (Sanger)PABP (PF00658)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00658    pfam00076   
Domain families : Smart (EMBL)PolyA (SM00517)  RRM (SM00360)  RRM_1 (SM00361)  
Conserved Domain (NCBI)PABPC1L
DMDM Disease mutations80336
Blocks (Seattle)PABPC1L
SuperfamilyQ4VXU2
Human Protein Atlas [tissue]ENSG00000101104-PABPC1L [tissue]
Peptide AtlasQ4VXU2
IPIIPI00556259   IPI00647824   IPI00607793   IPI00306870   IPI01016033   IPI00641237   IPI00643455   IPI00640219   
Protein Interaction databases
DIP (DOE-UCLA)Q4VXU2
IntAct (EBI)Q4VXU2
FunCoupENSG00000101104
BioGRIDPABPC1L
STRING (EMBL)PABPC1L
ZODIACPABPC1L
Ontologies - Pathways
QuickGOQ4VXU2
Ontology : AmiGOoocyte maturation  RNA binding  mRNA polyadenylation  chromatin-mediated maintenance of transcription  nucleus localization  extracellular exosome  
Ontology : EGO-EBIoocyte maturation  RNA binding  mRNA polyadenylation  chromatin-mediated maintenance of transcription  nucleus localization  extracellular exosome  
Pathways : KEGGRNA transport    mRNA surveillance pathway    RNA degradation   
NDEx NetworkPABPC1L
Atlas of Cancer Signalling NetworkPABPC1L
Wikipedia pathwaysPABPC1L
Orthology - Evolution
OrthoDB80336
GeneTree (enSembl)ENSG00000101104
Phylogenetic Trees/Animal Genes : TreeFamPABPC1L
HOVERGENQ4VXU2
HOGENOMQ4VXU2
Homologs : HomoloGenePABPC1L
Homology/Alignments : Family Browser (UCSC)PABPC1L
Gene fusions - Rearrangements
Tumor Fusion PortalPABPC1L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPABPC1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PABPC1L
dbVarPABPC1L
ClinVarPABPC1L
1000_GenomesPABPC1L 
Exome Variant ServerPABPC1L
ExAC (Exome Aggregation Consortium)ENSG00000101104
GNOMAD BrowserENSG00000101104
Genetic variants : HAPMAP80336
Genomic Variants (DGV)PABPC1L [DGVbeta]
DECIPHERPABPC1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPABPC1L 
Mutations
ICGC Data PortalPABPC1L 
TCGA Data PortalPABPC1L 
Broad Tumor PortalPABPC1L
OASIS PortalPABPC1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPABPC1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPABPC1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PABPC1L
DgiDB (Drug Gene Interaction Database)PABPC1L
DoCM (Curated mutations)PABPC1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PABPC1L (select a term)
intoGenPABPC1L
Cancer3DPABPC1L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPABPC1L
MedgenPABPC1L
Genetic Testing Registry PABPC1L
NextProtQ4VXU2 [Medical]
TSGene80336
GENETestsPABPC1L
Target ValidationPABPC1L
Huge Navigator PABPC1L [HugePedia]
snp3D : Map Gene to Disease80336
BioCentury BCIQPABPC1L
ClinGenPABPC1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80336
Chemical/Pharm GKB GenePA162398552
Clinical trialPABPC1L
Miscellaneous
canSAR (ICR)PABPC1L (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePABPC1L
EVEXPABPC1L
GoPubMedPABPC1L
iHOPPABPC1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:42:04 CET 2017

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