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PACRG (parkin coregulated)

Identity

Alias_symbol (synonym)PARK2CRG
FLJ32724
Glup
HAK005771
Other aliasGLUP
HGNC (Hugo) PACRG
LocusID (NCBI) 135138
Atlas_Id 45763
Location 6q26  [Link to chromosome band 6q26]
Location_base_pair Starts at 162727132 and ends at 163315492 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NSMCE2 (8q24.13) / PACRG (6q26)OTP (5q14.1) / PACRG (6q26)QKI (6q26) / PACRG (6q26)
NSMCE2 8q24.13 / PACRG 6q26QKI 6q26 / PACRG 6q26

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;8)(q26;q24) NSMCE2/PACRG


External links

Nomenclature
HGNC (Hugo)PACRG   19152
Cards
Entrez_Gene (NCBI)PACRG  135138  parkin coregulated
AliasesGLUP; HAK005771; PARK2CRG
GeneCards (Weizmann)PACRG
Ensembl hg19 (Hinxton)ENSG00000112530 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112530 [Gene_View]  ENSG00000112530 [Sequence]  chr6:162727132-163315492 [Contig_View]  PACRG [Vega]
ICGC DataPortalENSG00000112530
TCGA cBioPortalPACRG
AceView (NCBI)PACRG
Genatlas (Paris)PACRG
WikiGenes135138
SOURCE (Princeton)PACRG
Genetics Home Reference (NIH)PACRG
Genomic and cartography
GoldenPath hg38 (UCSC)PACRG  -     chr6:162727132-163315492 +  6q26   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PACRG  -     6q26   [Description]    (hg19-Feb_2009)
EnsemblPACRG - 6q26 [CytoView hg19]  PACRG - 6q26 [CytoView hg38]
Mapping of homologs : NCBIPACRG [Mapview hg19]  PACRG [Mapview hg38]
OMIM608427   
Gene and transcription
Genbank (Entrez)AF546872 AK023829 AK057286 BC030642 BC044227
RefSeq transcript (Entrez)NM_001080378 NM_001080379 NM_152410
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PACRG
Cluster EST : UnigeneHs.653916 [ NCBI ]
CGAP (NCI)Hs.653916
Alternative Splicing GalleryENSG00000112530
Gene ExpressionPACRG [ NCBI-GEO ]   PACRG [ EBI - ARRAY_EXPRESS ]   PACRG [ SEEK ]   PACRG [ MEM ]
Gene Expression Viewer (FireBrowse)PACRG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)135138
GTEX Portal (Tissue expression)PACRG
Human Protein AtlasENSG00000112530-PACRG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96M98   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96M98  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96M98
Splice isoforms : SwissVarQ96M98
PhosPhoSitePlusQ96M98
Domains : Interpro (EBI)Parkin_co-regulated_protein   
Domain families : Pfam (Sanger)ParcG (PF10274)   
Domain families : Pfam (NCBI)pfam10274   
Conserved Domain (NCBI)PACRG
DMDM Disease mutations135138
Blocks (Seattle)PACRG
SuperfamilyQ96M98
Human Protein Atlas [tissue]ENSG00000112530-PACRG [tissue]
Peptide AtlasQ96M98
HPRD07465
IPIIPI00065440   IPI00410380   IPI00973018   IPI01015419   IPI01012554   
Protein Interaction databases
DIP (DOE-UCLA)Q96M98
IntAct (EBI)Q96M98
FunCoupENSG00000112530
BioGRIDPACRG
STRING (EMBL)PACRG
ZODIACPACRG
Ontologies - Pathways
QuickGOQ96M98
Ontology : AmiGOG-protein coupled receptor binding  actin binding  nucleus  mitochondrion  cytosol  spermatid development  Hsp70 protein binding  heat shock protein binding  ubiquitin protein ligase binding  vesicle  cellular response to unfolded protein  neuron projection  alpha-tubulin binding  cell body  beta-tubulin binding  chaperone binding  Hsp90 protein binding  negative regulation of cell death  sperm midpiece  
Ontology : EGO-EBIG-protein coupled receptor binding  actin binding  nucleus  mitochondrion  cytosol  spermatid development  Hsp70 protein binding  heat shock protein binding  ubiquitin protein ligase binding  vesicle  cellular response to unfolded protein  neuron projection  alpha-tubulin binding  cell body  beta-tubulin binding  chaperone binding  Hsp90 protein binding  negative regulation of cell death  sperm midpiece  
NDEx NetworkPACRG
Atlas of Cancer Signalling NetworkPACRG
Wikipedia pathwaysPACRG
Orthology - Evolution
OrthoDB135138
GeneTree (enSembl)ENSG00000112530
Phylogenetic Trees/Animal Genes : TreeFamPACRG
HOVERGENQ96M98
HOGENOMQ96M98
Homologs : HomoloGenePACRG
Homology/Alignments : Family Browser (UCSC)PACRG
Gene fusions - Rearrangements
Fusion : MitelmanNSMCE2/PACRG [8q24.13/6q26]  [t(6;8)(q26;q24)]  
Fusion PortalNSMCE2 8q24.13 PACRG 6q26 HNSC
Fusion PortalQKI 6q26 PACRG 6q26 BRCA LUAD LUSC OV
Fusion : QuiverPACRG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPACRG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PACRG
dbVarPACRG
ClinVarPACRG
1000_GenomesPACRG 
Exome Variant ServerPACRG
ExAC (Exome Aggregation Consortium)ENSG00000112530
GNOMAD BrowserENSG00000112530
Genetic variants : HAPMAP135138
Genomic Variants (DGV)PACRG [DGVbeta]
DECIPHERPACRG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPACRG 
Mutations
ICGC Data PortalPACRG 
TCGA Data PortalPACRG 
Broad Tumor PortalPACRG
OASIS PortalPACRG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPACRG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPACRG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PACRG
DgiDB (Drug Gene Interaction Database)PACRG
DoCM (Curated mutations)PACRG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PACRG (select a term)
intoGenPACRG
Cancer3DPACRG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608427   
Orphanet
DisGeNETPACRG
MedgenPACRG
Genetic Testing Registry PACRG
NextProtQ96M98 [Medical]
TSGene135138
GENETestsPACRG
Target ValidationPACRG
Huge Navigator PACRG [HugePedia]
snp3D : Map Gene to Disease135138
BioCentury BCIQPACRG
ClinGenPACRG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD135138
Chemical/Pharm GKB GenePA134909011
Clinical trialPACRG
Miscellaneous
canSAR (ICR)PACRG (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePACRG
EVEXPACRG
GoPubMedPACRG
iHOPPACRG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:41:43 CEST 2018

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