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PACS2 (phosphofurin acidic cluster sorting protein 2)

Identity

Alias_namesPACS1L
phosphofurin acidic cluster sorting protein 1-like
Alias_symbol (synonym)KIAA0602
Other aliasPACS-2
HGNC (Hugo) PACS2
LocusID (NCBI) 23241
Atlas_Id 52900
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 105780752 and ends at 105864484 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MTA1 (14q32.33) / PACS2 (14q32.33)PACS2 (14q32.33) / ADGRA2 (8p11.23)PACS2 (14q32.33) / APLP2 (11q24.3)
PACS2 (14q32.33) / MAP3K12 (12q13.13)PACS2 (14q32.33) / PACS2 (14q32.33)SMARCC1 (3p21.31) / PACS2 (14q32.33)
MTA1 14q32.33 / PACS2 14q32.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PACS2   23794
Cards
Entrez_Gene (NCBI)PACS2  23241  phosphofurin acidic cluster sorting protein 2
AliasesPACS-2; PACS1L
GeneCards (Weizmann)PACS2
Ensembl hg19 (Hinxton)ENSG00000179364 [Gene_View]  chr14:105780752-105864484 [Contig_View]  PACS2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000179364 [Gene_View]  chr14:105780752-105864484 [Contig_View]  PACS2 [Vega]
ICGC DataPortalENSG00000179364
TCGA cBioPortalPACS2
AceView (NCBI)PACS2
Genatlas (Paris)PACS2
WikiGenes23241
SOURCE (Princeton)PACS2
Genetics Home Reference (NIH)PACS2
Genomic and cartography
GoldenPath hg19 (UCSC)PACS2  -     chr14:105780752-105864484 +  14q32.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PACS2  -     14q32.33   [Description]    (hg38-Dec_2013)
EnsemblPACS2 - 14q32.33 [CytoView hg19]  PACS2 - 14q32.33 [CytoView hg38]
Mapping of homologs : NCBIPACS2 [Mapview hg19]  PACS2 [Mapview hg38]
OMIM610423   
Gene and transcription
Genbank (Entrez)AB011174 AB029326 AB072449 AK098354 AL539052
RefSeq transcript (Entrez)NM_001100913 NM_001243127 NM_015197
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)PACS2
Cluster EST : UnigeneHs.525626 [ NCBI ]
CGAP (NCI)Hs.525626
Alternative Splicing GalleryENSG00000179364
Gene ExpressionPACS2 [ NCBI-GEO ]   PACS2 [ EBI - ARRAY_EXPRESS ]   PACS2 [ SEEK ]   PACS2 [ MEM ]
Gene Expression Viewer (FireBrowse)PACS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23241
GTEX Portal (Tissue expression)PACS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VP3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VP3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VP3
Splice isoforms : SwissVarQ86VP3
PhosPhoSitePlusQ86VP3
Domains : Interpro (EBI)Phosphofurin_acidic_CS-1   
Domain families : Pfam (Sanger)Pacs-1 (PF10254)   
Domain families : Pfam (NCBI)pfam10254   
Conserved Domain (NCBI)PACS2
DMDM Disease mutations23241
Blocks (Seattle)PACS2
SuperfamilyQ86VP3
Human Protein AtlasENSG00000179364
Peptide AtlasQ86VP3
HPRD17816
IPIIPI00029041   IPI00789787   IPI00879553   IPI00940128   IPI00384604   IPI00167220   IPI01021211   IPI01022561   IPI01022725   IPI01022260   IPI01022440   
Protein Interaction databases
DIP (DOE-UCLA)Q86VP3
IntAct (EBI)Q86VP3
FunCoupENSG00000179364
BioGRIDPACS2
STRING (EMBL)PACS2
ZODIACPACS2
Ontologies - Pathways
QuickGOQ86VP3
Ontology : AmiGOautophagosome assembly  mitochondrion  endoplasmic reticulum  endoplasmic reticulum lumen  apoptotic process  viral process  protein localization to pre-autophagosomal structure  ion channel binding  protein targeting to plasma membrane  
Ontology : EGO-EBIautophagosome assembly  mitochondrion  endoplasmic reticulum  endoplasmic reticulum lumen  apoptotic process  viral process  protein localization to pre-autophagosomal structure  ion channel binding  protein targeting to plasma membrane  
NDEx NetworkPACS2
Atlas of Cancer Signalling NetworkPACS2
Wikipedia pathwaysPACS2
Orthology - Evolution
OrthoDB23241
GeneTree (enSembl)ENSG00000179364
Phylogenetic Trees/Animal Genes : TreeFamPACS2
HOVERGENQ86VP3
HOGENOMQ86VP3
Homologs : HomoloGenePACS2
Homology/Alignments : Family Browser (UCSC)PACS2
Gene fusions - Rearrangements
Fusion : MitelmanMTA1/PACS2 [14q32.33/14q32.33]  [t(14;14)(q32;q32)]  
Fusion: TCGAMTA1 14q32.33 PACS2 14q32.33 BRCA HNSC LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPACS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PACS2
dbVarPACS2
ClinVarPACS2
1000_GenomesPACS2 
Exome Variant ServerPACS2
ExAC (Exome Aggregation Consortium)PACS2 (select the gene name)
Genetic variants : HAPMAP23241
Genomic Variants (DGV)PACS2 [DGVbeta]
DECIPHER (Syndromes)14:105780752-105864484  ENSG00000179364
CONAN: Copy Number AnalysisPACS2 
Mutations
ICGC Data PortalPACS2 
TCGA Data PortalPACS2 
Broad Tumor PortalPACS2
OASIS PortalPACS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPACS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPACS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PACS2
DgiDB (Drug Gene Interaction Database)PACS2
DoCM (Curated mutations)PACS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PACS2 (select a term)
intoGenPACS2
Cancer3DPACS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610423   
Orphanet
MedgenPACS2
Genetic Testing Registry PACS2
NextProtQ86VP3 [Medical]
TSGene23241
GENETestsPACS2
Huge Navigator PACS2 [HugePedia]
snp3D : Map Gene to Disease23241
BioCentury BCIQPACS2
ClinGenPACS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23241
Chemical/Pharm GKB GenePA134941470
Clinical trialPACS2
Miscellaneous
canSAR (ICR)PACS2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePACS2
EVEXPACS2
GoPubMedPACS2
iHOPPACS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:13:24 CEST 2017

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