Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PACSIN1 (protein kinase C and casein kinase substrate in neurons 1)

Identity

Alias_symbol (synonym)SDPI
Other alias
HGNC (Hugo) PACSIN1
LocusID (NCBI) 29993
Atlas_Id 71624
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 34514872 and ends at 34535223 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SAYSD1 (6p21.2) / PACSIN1 (6p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p21;p21) SAYSD1/PACSIN1


External links

Nomenclature
HGNC (Hugo)PACSIN1   8570
Cards
Entrez_Gene (NCBI)PACSIN1  29993  protein kinase C and casein kinase substrate in neurons 1
AliasesSDPI
GeneCards (Weizmann)PACSIN1
Ensembl hg19 (Hinxton)ENSG00000124507 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124507 [Gene_View]  ENSG00000124507 [Sequence]  chr6:34514872-34535223 [Contig_View]  PACSIN1 [Vega]
ICGC DataPortalENSG00000124507
TCGA cBioPortalPACSIN1
AceView (NCBI)PACSIN1
Genatlas (Paris)PACSIN1
WikiGenes29993
SOURCE (Princeton)PACSIN1
Genetics Home Reference (NIH)PACSIN1
Genomic and cartography
GoldenPath hg38 (UCSC)PACSIN1  -     chr6:34514872-34535223 +  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PACSIN1  -     6p21.31   [Description]    (hg19-Feb_2009)
EnsemblPACSIN1 - 6p21.31 [CytoView hg19]  PACSIN1 - 6p21.31 [CytoView hg38]
Mapping of homologs : NCBIPACSIN1 [Mapview hg19]  PACSIN1 [Mapview hg38]
OMIM606512   
Gene and transcription
Genbank (Entrez)AB037800 AF242529 AK289956 AK294132 AL834211
RefSeq transcript (Entrez)NM_001199583 NM_020804
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PACSIN1
Cluster EST : UnigeneHs.520087 [ NCBI ]
CGAP (NCI)Hs.520087
Alternative Splicing GalleryENSG00000124507
Gene ExpressionPACSIN1 [ NCBI-GEO ]   PACSIN1 [ EBI - ARRAY_EXPRESS ]   PACSIN1 [ SEEK ]   PACSIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)PACSIN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29993
GTEX Portal (Tissue expression)PACSIN1
Human Protein AtlasENSG00000124507-PACSIN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BY11   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BY11  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BY11
Splice isoforms : SwissVarQ9BY11
PhosPhoSitePlusQ9BY11
Domaine pattern : Prosite (Expaxy)F_BAR (PS51741)    SH3 (PS50002)   
Domains : Interpro (EBI)F_BAR    FCH_dom    PACSIN1    SH3_domain   
Domain families : Pfam (Sanger)FCH (PF00611)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam00611    pfam14604   
Domain families : Smart (EMBL)FCH (SM00055)  SH3 (SM00326)  
Conserved Domain (NCBI)PACSIN1
DMDM Disease mutations29993
Blocks (Seattle)PACSIN1
PDB (SRS)3HAH    3HAI    3Q84    3QNI   
PDB (PDBSum)3HAH    3HAI    3Q84    3QNI   
PDB (IMB)3HAH    3HAI    3Q84    3QNI   
PDB (RSDB)3HAH    3HAI    3Q84    3QNI   
Structural Biology KnowledgeBase3HAH    3HAI    3Q84    3QNI   
SCOP (Structural Classification of Proteins)3HAH    3HAI    3Q84    3QNI   
CATH (Classification of proteins structures)3HAH    3HAI    3Q84    3QNI   
SuperfamilyQ9BY11
Human Protein Atlas [tissue]ENSG00000124507-PACSIN1 [tissue]
Peptide AtlasQ9BY11
HPRD05936
IPIIPI00011515   IPI01013099   IPI00644509   
Protein Interaction databases
DIP (DOE-UCLA)Q9BY11
IntAct (EBI)Q9BY11
FunCoupENSG00000124507
BioGRIDPACSIN1
STRING (EMBL)PACSIN1
ZODIACPACSIN1
Ontologies - Pathways
QuickGOQ9BY11
Ontology : AmiGO###############################################################################################################################################################################################################################################################  
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################  
NDEx NetworkPACSIN1
Atlas of Cancer Signalling NetworkPACSIN1
Wikipedia pathwaysPACSIN1
Orthology - Evolution
OrthoDB29993
GeneTree (enSembl)ENSG00000124507
Phylogenetic Trees/Animal Genes : TreeFamPACSIN1
HOVERGENQ9BY11
HOGENOMQ9BY11
Homologs : HomoloGenePACSIN1
Homology/Alignments : Family Browser (UCSC)PACSIN1
Gene fusions - Rearrangements
Fusion : QuiverPACSIN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPACSIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PACSIN1
dbVarPACSIN1
ClinVarPACSIN1
1000_GenomesPACSIN1 
Exome Variant ServerPACSIN1
ExAC (Exome Aggregation Consortium)ENSG00000124507
GNOMAD BrowserENSG00000124507
Varsome BrowserPACSIN1
Genetic variants : HAPMAP29993
Genomic Variants (DGV)PACSIN1 [DGVbeta]
DECIPHERPACSIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPACSIN1 
Mutations
ICGC Data PortalPACSIN1 
TCGA Data PortalPACSIN1 
Broad Tumor PortalPACSIN1
OASIS PortalPACSIN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPACSIN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPACSIN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PACSIN1
DgiDB (Drug Gene Interaction Database)PACSIN1
DoCM (Curated mutations)PACSIN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PACSIN1 (select a term)
intoGenPACSIN1
Cancer3DPACSIN1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606512   
Orphanet
DisGeNETPACSIN1
MedgenPACSIN1
Genetic Testing Registry PACSIN1
NextProtQ9BY11 [Medical]
TSGene29993
GENETestsPACSIN1
Target ValidationPACSIN1
Huge Navigator PACSIN1 [HugePedia]
snp3D : Map Gene to Disease29993
BioCentury BCIQPACSIN1
ClinGenPACSIN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29993
Chemical/Pharm GKB GenePA32896
Clinical trialPACSIN1
Miscellaneous
canSAR (ICR)PACSIN1 (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePACSIN1
EVEXPACSIN1
GoPubMedPACSIN1
iHOPPACSIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:22:54 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.