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PAG1 (phosphoprotein membrane anchor with glycosphingolipid microdomains 1)

Identity

Alias (NCBI)CBP
PAG
HGNC (Hugo) PAG1
HGNC Alias symbPAG
CBP
HGNC Alias nameCsk-binding protein
 transmembrane adaptor protein PAG
HGNC Previous namephosphoprotein associated with glycosphingolipid microdomains 1
LocusID (NCBI) 55824
Atlas_Id 50191
Location 8q21.13  [Link to chromosome band 8q21]
Location_base_pair Starts at 80967811 and ends at 81112068 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LSM14A (19q13.11)::PAG1 (8q21.13)PAG1 (8q21.13)::ARIH2 (3p21.31)PAG1 (8q21.13)::PAG1 (8q21.13)
PAG1 (8q21.13)::STYX (14q22.1)ZNF704 (8q21.13)::PAG1 (8q21.13)ZNF704 8q21.13::PAG1 8q21.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PAG1   30043
Cards
Entrez_Gene (NCBI)PAG1    phosphoprotein membrane anchor with glycosphingolipid microdomains 1
AliasesCBP; PAG
GeneCards (Weizmann)PAG1
Ensembl hg19 (Hinxton)ENSG00000076641 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000076641 [Gene_View]  ENSG00000076641 [Sequence]  chr8:80967811-81112068 [Contig_View]  PAG1 [Vega]
ICGC DataPortalENSG00000076641
TCGA cBioPortalPAG1
AceView (NCBI)PAG1
Genatlas (Paris)PAG1
SOURCE (Princeton)PAG1
Genetics Home Reference (NIH)PAG1
Genomic and cartography
GoldenPath hg38 (UCSC)PAG1  -     chr8:80967811-81112068 -  8q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAG1  -     8q21.13   [Description]    (hg19-Feb_2009)
GoldenPathPAG1 - 8q21.13 [CytoView hg19]  PAG1 - 8q21.13 [CytoView hg38]
ImmunoBaseENSG00000076641
Genome Data Viewer NCBIPAG1 [Mapview hg19]  
OMIM605767   
Gene and transcription
Genbank (Entrez)AA766638 AF240634 AK000680 AK095177 AK289818
RefSeq transcript (Entrez)NM_001007549 NM_018440
Consensus coding sequences : CCDS (NCBI)PAG1
Gene ExpressionPAG1 [ NCBI-GEO ]   PAG1 [ EBI - ARRAY_EXPRESS ]   PAG1 [ SEEK ]   PAG1 [ MEM ]
Gene Expression Viewer (FireBrowse)PAG1 [ Firebrowse - Broad ]
GenevisibleExpression of PAG1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55824
GTEX Portal (Tissue expression)PAG1
Human Protein AtlasENSG00000076641-PAG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWQ8
PhosPhoSitePlusQ9NWQ8
Domains : Interpro (EBI)PAG   
Domain families : Pfam (Sanger)PAG (PF15347)   
Domain families : Pfam (NCBI)pfam15347   
Conserved Domain (NCBI)PAG1
SuperfamilyQ9NWQ8
AlphaFold pdb e-kbQ9NWQ8   
Human Protein Atlas [tissue]ENSG00000076641-PAG1 [tissue]
HPRD05772
Protein Interaction databases
DIP (DOE-UCLA)Q9NWQ8
IntAct (EBI)Q9NWQ8
BioGRIDPAG1
STRING (EMBL)PAG1
ZODIACPAG1
Ontologies - Pathways
QuickGOQ9NWQ8
Ontology : AmiGOadaptive immune response  protein binding  plasma membrane  plasma membrane  signal transduction  integral component of membrane  intracellular signal transduction  intracellular signal transduction  signaling adaptor activity  SH2 domain binding  SH2 domain binding  membrane raft  membrane raft  regulation of T cell activation  negative regulation of T cell activation  
Ontology : EGO-EBIadaptive immune response  protein binding  plasma membrane  plasma membrane  signal transduction  integral component of membrane  intracellular signal transduction  intracellular signal transduction  signaling adaptor activity  SH2 domain binding  SH2 domain binding  membrane raft  membrane raft  regulation of T cell activation  negative regulation of T cell activation  
NDEx NetworkPAG1
Atlas of Cancer Signalling NetworkPAG1
Wikipedia pathwaysPAG1
Orthology - Evolution
OrthoDB55824
GeneTree (enSembl)ENSG00000076641
Phylogenetic Trees/Animal Genes : TreeFamPAG1
Homologs : HomoloGenePAG1
Homology/Alignments : Family Browser (UCSC)PAG1
Gene fusions - Rearrangements
Fusion : MitelmanZNF704::PAG1 [8q21.13/8q21.13]  
Fusion : QuiverPAG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAG1
dbVarPAG1
ClinVarPAG1
MonarchPAG1
1000_GenomesPAG1 
Exome Variant ServerPAG1
GNOMAD BrowserENSG00000076641
Varsome BrowserPAG1
ACMGPAG1 variants
VarityQ9NWQ8
Genomic Variants (DGV)PAG1 [DGVbeta]
DECIPHERPAG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAG1 
Mutations
ICGC Data PortalPAG1 
TCGA Data PortalPAG1 
Broad Tumor PortalPAG1
OASIS PortalPAG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAG1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPAG1
Mutations and Diseases : HGMDPAG1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPAG1
DgiDB (Drug Gene Interaction Database)PAG1
DoCM (Curated mutations)PAG1
CIViC (Clinical Interpretations of Variants in Cancer)PAG1
Cancer3DPAG1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605767   
Orphanet
DisGeNETPAG1
MedgenPAG1
Genetic Testing Registry PAG1
NextProtQ9NWQ8 [Medical]
GENETestsPAG1
Target ValidationPAG1
Huge Navigator PAG1 [HugePedia]
ClinGenPAG1
Clinical trials, drugs, therapy
MyCancerGenomePAG1
Protein Interactions : CTDPAG1
Pharm GKB GenePA142671201
PharosQ9NWQ8
Clinical trialPAG1
Miscellaneous
canSAR (ICR)PAG1
HarmonizomePAG1
ARCHS4PAG1
DataMed IndexPAG1
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPAG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:51:00 CET 2022

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