Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PAK1IP1 (PAK1 interacting protein 1)

Identity

Alias_symbol (synonym)FLJ20624
hPIP1
PIP1
bA421M1.5
MAK11
WDR84
Other alias
HGNC (Hugo) PAK1IP1
LocusID (NCBI) 55003
Atlas_Id 53823
Location 6p24.2  [Link to chromosome band 6p24]
Location_base_pair Starts at 10694955 and ends at 10709737 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TMEM14C (6p24.2) / PAK1IP1 (6p24.2)TSPAN13 (7p21.1) / PAK1IP1 (6p24.2)TMEM14C 6p24.2 / PAK1IP1 6p24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PAK1IP1   20882
Cards
Entrez_Gene (NCBI)PAK1IP1  55003  PAK1 interacting protein 1
AliasesMAK11; PIP1; WDR84; bA421M1.5; 
hPIP1
GeneCards (Weizmann)PAK1IP1
Ensembl hg19 (Hinxton)ENSG00000111845 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111845 [Gene_View]  chr6:10694955-10709737 [Contig_View]  PAK1IP1 [Vega]
ICGC DataPortalENSG00000111845
TCGA cBioPortalPAK1IP1
AceView (NCBI)PAK1IP1
Genatlas (Paris)PAK1IP1
WikiGenes55003
SOURCE (Princeton)PAK1IP1
Genetics Home Reference (NIH)PAK1IP1
Genomic and cartography
GoldenPath hg38 (UCSC)PAK1IP1  -     chr6:10694955-10709737 +  6p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAK1IP1  -     6p24.2   [Description]    (hg19-Feb_2009)
EnsemblPAK1IP1 - 6p24.2 [CytoView hg19]  PAK1IP1 - 6p24.2 [CytoView hg38]
Mapping of homologs : NCBIPAK1IP1 [Mapview hg19]  PAK1IP1 [Mapview hg38]
OMIM607811   
Gene and transcription
Genbank (Entrez)AF283303 AK000631 AK225516 BC010907 BU618231
RefSeq transcript (Entrez)NM_017906
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAK1IP1
Cluster EST : UnigeneHs.310231 [ NCBI ]
CGAP (NCI)Hs.310231
Alternative Splicing GalleryENSG00000111845
Gene ExpressionPAK1IP1 [ NCBI-GEO ]   PAK1IP1 [ EBI - ARRAY_EXPRESS ]   PAK1IP1 [ SEEK ]   PAK1IP1 [ MEM ]
Gene Expression Viewer (FireBrowse)PAK1IP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55003
GTEX Portal (Tissue expression)PAK1IP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWT1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWT1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWT1
Splice isoforms : SwissVarQ9NWT1
PhosPhoSitePlusQ9NWT1
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)PAK1IP1
DMDM Disease mutations55003
Blocks (Seattle)PAK1IP1
SuperfamilyQ9NWT1
Human Protein AtlasENSG00000111845
Peptide AtlasQ9NWT1
HPRD07424
IPIIPI00549540   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWT1
IntAct (EBI)Q9NWT1
FunCoupENSG00000111845
BioGRIDPAK1IP1
STRING (EMBL)PAK1IP1
ZODIACPAK1IP1
Ontologies - Pathways
QuickGOQ9NWT1
Ontology : AmiGOprotein binding  nucleolus  cell proliferation  negative regulation of signal transduction  palate development  
Ontology : EGO-EBIprotein binding  nucleolus  cell proliferation  negative regulation of signal transduction  palate development  
NDEx NetworkPAK1IP1
Atlas of Cancer Signalling NetworkPAK1IP1
Wikipedia pathwaysPAK1IP1
Orthology - Evolution
OrthoDB55003
GeneTree (enSembl)ENSG00000111845
Phylogenetic Trees/Animal Genes : TreeFamPAK1IP1
HOVERGENQ9NWT1
HOGENOMQ9NWT1
Homologs : HomoloGenePAK1IP1
Homology/Alignments : Family Browser (UCSC)PAK1IP1
Gene fusions - Rearrangements
Fusion : MitelmanTMEM14C/PAK1IP1 [6p24.2/6p24.2]  [t(6;6)(p24;p24)]  
Fusion: TCGATMEM14C 6p24.2 PAK1IP1 6p24.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAK1IP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAK1IP1
dbVarPAK1IP1
ClinVarPAK1IP1
1000_GenomesPAK1IP1 
Exome Variant ServerPAK1IP1
ExAC (Exome Aggregation Consortium)PAK1IP1 (select the gene name)
Genetic variants : HAPMAP55003
Genomic Variants (DGV)PAK1IP1 [DGVbeta]
DECIPHERPAK1IP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAK1IP1 
Mutations
ICGC Data PortalPAK1IP1 
TCGA Data PortalPAK1IP1 
Broad Tumor PortalPAK1IP1
OASIS PortalPAK1IP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAK1IP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPAK1IP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAK1IP1
DgiDB (Drug Gene Interaction Database)PAK1IP1
DoCM (Curated mutations)PAK1IP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAK1IP1 (select a term)
intoGenPAK1IP1
Cancer3DPAK1IP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607811   
Orphanet
MedgenPAK1IP1
Genetic Testing Registry PAK1IP1
NextProtQ9NWT1 [Medical]
TSGene55003
GENETestsPAK1IP1
Target ValidationPAK1IP1
Huge Navigator PAK1IP1 [HugePedia]
snp3D : Map Gene to Disease55003
BioCentury BCIQPAK1IP1
ClinGenPAK1IP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55003
Chemical/Pharm GKB GenePA134928299
Clinical trialPAK1IP1
Miscellaneous
canSAR (ICR)PAK1IP1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAK1IP1
EVEXPAK1IP1
GoPubMedPAK1IP1
iHOPPAK1IP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 14:02:35 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.