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PALM2-AKAP2 (PALM2-AKAP2 fusion)

Identity

Other aliasAKAP-2
AKAP-KL
AKAP2
AKAPKL
MISP2
PALM2
PRKA2
HGNC (Hugo) PALM2-AKAP2
LocusID (NCBI) 445815
Atlas_Id 58009
Location 9q31.3  [Link to chromosome band 9q31]
Location_base_pair Starts at 109780297 and ends at 110172511 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC141 (2q31.2) / PALM2-AKAP2 (9q31.3)PALM2-AKAP2 (9q31.3) / FGF18 (5q35.1)SHB (9p13.2) / PALM2-AKAP2 (9q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(9;9)(p13;q31) SHB/PALM2-AKAP2


External links

Nomenclature
HGNC (Hugo)PALM2-AKAP2   33529
Cards
Entrez_Gene (NCBI)PALM2-AKAP2  445815  PALM2-AKAP2 fusion
AliasesAKAP-2; AKAP-KL; AKAP2; AKAPKL; 
MISP2; PALM2; PRKA2
GeneCards (Weizmann)PALM2-AKAP2
Ensembl hg19 (Hinxton)ENSG00000157654 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157654 [Gene_View]  ENSG00000157654 [Sequence]  chr9:109780297-110172511 [Contig_View]  PALM2-AKAP2 [Vega]
ICGC DataPortalENSG00000157654
TCGA cBioPortalPALM2-AKAP2
AceView (NCBI)PALM2-AKAP2
Genatlas (Paris)PALM2-AKAP2
WikiGenes445815
SOURCE (Princeton)PALM2-AKAP2
Genetics Home Reference (NIH)PALM2-AKAP2
Genomic and cartography
GoldenPath hg38 (UCSC)PALM2-AKAP2  -     chr9:109780297-110172511 +  9q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PALM2-AKAP2  -     9q31.3   [Description]    (hg19-Feb_2009)
GoldenPathPALM2-AKAP2 - 9q31.3 [CytoView hg19]  PALM2-AKAP2 - 9q31.3 [CytoView hg38]
ImmunoBaseENSG00000157654
Mapping of homologs : NCBIPALM2-AKAP2 [Mapview hg19]  PALM2-AKAP2 [Mapview hg38]
OMIM604582   
Gene and transcription
Genbank (Entrez)AB023137 AJ303079 AJ312216 AJ312217 AJ420463
RefSeq transcript (Entrez)NM_001004065 NM_001037293 NM_001136562 NM_001198656 NM_007203 NM_053016 NM_147150
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PALM2-AKAP2
Cluster EST : UnigeneHs.591908 [ NCBI ]
CGAP (NCI)Hs.591908
Alternative Splicing GalleryENSG00000157654
Gene ExpressionPALM2-AKAP2 [ NCBI-GEO ]   PALM2-AKAP2 [ EBI - ARRAY_EXPRESS ]   PALM2-AKAP2 [ SEEK ]   PALM2-AKAP2 [ MEM ]
Gene Expression Viewer (FireBrowse)PALM2-AKAP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)445815
GTEX Portal (Tissue expression)PALM2-AKAP2
Human Protein AtlasENSG00000157654-PALM2-AKAP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IXS6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IXS6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IXS6
Splice isoforms : SwissVarQ8IXS6
PhosPhoSitePlusQ8IXS6
Domains : Interpro (EBI)Paralemmin   
Domain families : Pfam (Sanger)Paralemmin (PF03285)   
Domain families : Pfam (NCBI)pfam03285   
Conserved Domain (NCBI)PALM2-AKAP2
DMDM Disease mutations445815
Blocks (Seattle)PALM2-AKAP2
SuperfamilyQ8IXS6
Human Protein Atlas [tissue]ENSG00000157654-PALM2-AKAP2 [tissue]
Peptide AtlasQ8IXS6
Protein Interaction databases
DIP (DOE-UCLA)Q8IXS6
IntAct (EBI)Q8IXS6
FunCoupENSG00000157654
BioGRIDPALM2-AKAP2
STRING (EMBL)PALM2-AKAP2
ZODIACPALM2-AKAP2
Ontologies - Pathways
QuickGOQ8IXS6
Ontology : AmiGOplasma membrane  regulation of cell shape  
Ontology : EGO-EBIplasma membrane  regulation of cell shape  
NDEx NetworkPALM2-AKAP2
Atlas of Cancer Signalling NetworkPALM2-AKAP2
Wikipedia pathwaysPALM2-AKAP2
Orthology - Evolution
OrthoDB445815
GeneTree (enSembl)ENSG00000157654
Phylogenetic Trees/Animal Genes : TreeFamPALM2-AKAP2
HOGENOMQ8IXS6
Homologs : HomoloGenePALM2-AKAP2
Homology/Alignments : Family Browser (UCSC)PALM2-AKAP2
Gene fusions - Rearrangements
Fusion : QuiverPALM2-AKAP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPALM2-AKAP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PALM2-AKAP2
dbVarPALM2-AKAP2
ClinVarPALM2-AKAP2
1000_GenomesPALM2-AKAP2 
Exome Variant ServerPALM2-AKAP2
ExAC (Exome Aggregation Consortium)ENSG00000157654
GNOMAD BrowserENSG00000157654
Varsome BrowserPALM2-AKAP2
Genetic variants : HAPMAP445815
Genomic Variants (DGV)PALM2-AKAP2 [DGVbeta]
DECIPHERPALM2-AKAP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPALM2-AKAP2 
Mutations
ICGC Data PortalPALM2-AKAP2 
TCGA Data PortalPALM2-AKAP2 
Broad Tumor PortalPALM2-AKAP2
OASIS PortalPALM2-AKAP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPALM2-AKAP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPALM2-AKAP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PALM2-AKAP2
DgiDB (Drug Gene Interaction Database)PALM2-AKAP2
DoCM (Curated mutations)PALM2-AKAP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PALM2-AKAP2 (select a term)
intoGenPALM2-AKAP2
Cancer3DPALM2-AKAP2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604582   
Orphanet
DisGeNETPALM2-AKAP2
MedgenPALM2-AKAP2
Genetic Testing Registry PALM2-AKAP2
NextProtQ8IXS6 [Medical]
TSGene445815
GENETestsPALM2-AKAP2
Target ValidationPALM2-AKAP2
Huge Navigator PALM2-AKAP2 [HugePedia]
snp3D : Map Gene to Disease445815
BioCentury BCIQPALM2-AKAP2
ClinGenPALM2-AKAP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD445815
Chemical/Pharm GKB GenePA162398639
Clinical trialPALM2-AKAP2
Miscellaneous
canSAR (ICR)PALM2-AKAP2 (select the gene name)
DataMed IndexPALM2-AKAP2
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePALM2-AKAP2
EVEXPALM2-AKAP2
GoPubMedPALM2-AKAP2
iHOPPALM2-AKAP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 8 11:34:20 CEST 2019

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