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PAM16 (presequence translocase associated motor 16)

Identity

Alias (NCBI)CGI-136
MAGMAS
SMDMDM
TIM16
TIMM16
HGNC (Hugo) PAM16
HGNC Alias symbMagmas
Tim16
TIMM16
HGNC Alias namemitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction
HGNC Previous namepresequence translocase-associated motor 16 homolog (S. cerevisiae)
 presequence translocase associated motor 16 homolog
LocusID (NCBI) 51025
Atlas_Id 51663
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 4340251 and ends at 4351321 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CORO7 (16p13.3) / PAM16 (16p13.3)LPXN (11q12.1) / PAM16 (16p13.3)PAM16 (16p13.3) / CORO7 (16p13.3)
PAM16 (16p13.3) / TSPAN3 (15q24.3)PAM16 16p13.3 / CORO7 16p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PAM16   29679
Cards
Entrez_Gene (NCBI)PAM16    presequence translocase associated motor 16
AliasesCGI-136; MAGMAS; SMDMDM; TIM16; 
TIMM16
GeneCards (Weizmann)PAM16
Ensembl hg19 (Hinxton)ENSG00000217930 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000217930 [Gene_View]  ENSG00000217930 [Sequence]  chr16:4340251-4351321 [Contig_View]  PAM16 [Vega]
ICGC DataPortalENSG00000217930
TCGA cBioPortalPAM16
AceView (NCBI)PAM16
Genatlas (Paris)PAM16
SOURCE (Princeton)PAM16
Genetics Home Reference (NIH)PAM16
Genomic and cartography
GoldenPath hg38 (UCSC)PAM16  -     chr16:4340251-4351321 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAM16  -     16p13.3   [Description]    (hg19-Feb_2009)
GoldenPathPAM16 - 16p13.3 [CytoView hg19]  PAM16 - 16p13.3 [CytoView hg38]
ImmunoBaseENSG00000217930
Genome Data Viewer NCBIPAM16 [Mapview hg19]  
OMIM613320   614336   
Gene and transcription
Genbank (Entrez)AF151894 AF349455 AK026514 BC005024 BG715429
RefSeq transcript (Entrez)NM_016069
Consensus coding sequences : CCDS (NCBI)PAM16
Gene ExpressionPAM16 [ NCBI-GEO ]   PAM16 [ EBI - ARRAY_EXPRESS ]   PAM16 [ SEEK ]   PAM16 [ MEM ]
Gene Expression Viewer (FireBrowse)PAM16 [ Firebrowse - Broad ]
GenevisibleExpression of PAM16 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51025
GTEX Portal (Tissue expression)PAM16
Human Protein AtlasENSG00000217930-PAM16 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3D7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3D7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3D7
PhosPhoSitePlusQ9Y3D7
Domains : Interpro (EBI)J_dom_sf    Tim16   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PAM16
SuperfamilyQ9Y3D7
AlphaFold pdb e-kbQ9Y3D7   
Human Protein Atlas [tissue]ENSG00000217930-PAM16 [tissue]
HPRD14798
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3D7
IntAct (EBI)Q9Y3D7
BioGRIDPAM16
STRING (EMBL)PAM16
ZODIACPAM16
Ontologies - Pathways
QuickGOQ9Y3D7
Ontology : AmiGOPAM complex, Tim23 associated import motor  PAM complex, Tim23 associated import motor  ossification  protein binding  TIM23 mitochondrial import inner membrane translocase complex  mitochondrial matrix  protein import into mitochondrial matrix  protein import into mitochondrial matrix  extrinsic component of mitochondrial inner membrane  negative regulation of ATPase activity  protein-containing complex  negative regulation of release of cytochrome c from mitochondria  negative regulation of apoptotic DNA fragmentation  
Ontology : EGO-EBIPAM complex, Tim23 associated import motor  PAM complex, Tim23 associated import motor  ossification  protein binding  TIM23 mitochondrial import inner membrane translocase complex  mitochondrial matrix  protein import into mitochondrial matrix  protein import into mitochondrial matrix  extrinsic component of mitochondrial inner membrane  negative regulation of ATPase activity  protein-containing complex  negative regulation of release of cytochrome c from mitochondria  negative regulation of apoptotic DNA fragmentation  
NDEx NetworkPAM16
Atlas of Cancer Signalling NetworkPAM16
Wikipedia pathwaysPAM16
Orthology - Evolution
OrthoDB51025
GeneTree (enSembl)ENSG00000217930
Phylogenetic Trees/Animal Genes : TreeFamPAM16
Homologs : HomoloGenePAM16
Homology/Alignments : Family Browser (UCSC)PAM16
Gene fusions - Rearrangements
Fusion : MitelmanPAM16/CORO7 [16p13.3/16p13.3]  
Fusion : QuiverPAM16
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAM16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAM16
dbVarPAM16
ClinVarPAM16
MonarchPAM16
1000_GenomesPAM16 
Exome Variant ServerPAM16
GNOMAD BrowserENSG00000217930
Varsome BrowserPAM16
ACMGPAM16 variants
VarityQ9Y3D7
Genomic Variants (DGV)PAM16 [DGVbeta]
DECIPHERPAM16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAM16 
Mutations
ICGC Data PortalPAM16 
TCGA Data PortalPAM16 
Broad Tumor PortalPAM16
OASIS PortalPAM16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAM16  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPAM16
Mutations and Diseases : HGMDPAM16
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPAM16
DgiDB (Drug Gene Interaction Database)PAM16
DoCM (Curated mutations)PAM16
CIViC (Clinical Interpretations of Variants in Cancer)PAM16
Cancer3DPAM16
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613320    614336   
Orphanet22862   
DisGeNETPAM16
MedgenPAM16
Genetic Testing Registry PAM16
NextProtQ9Y3D7 [Medical]
GENETestsPAM16
Target ValidationPAM16
Huge Navigator PAM16 [HugePedia]
ClinGenPAM16
Clinical trials, drugs, therapy
MyCancerGenomePAM16
Protein Interactions : CTDPAM16
Pharm GKB GenePA166048989
PharosQ9Y3D7
Clinical trialPAM16
Miscellaneous
canSAR (ICR)PAM16
HarmonizomePAM16
DataMed IndexPAM16
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPAM16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:24:14 CEST 2021

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