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PANX3 (pannexin 3)

Identity

Alias_symbol (synonym)Px3
Other aliasPX3
HGNC (Hugo) PANX3
LocusID (NCBI) 116337
Atlas_Id 54912
Location 11q24.2  [Link to chromosome band 11q24]
Location_base_pair Starts at 124611557 and ends at 124620355 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PANX3   20573
Cards
Entrez_Gene (NCBI)PANX3  116337  pannexin 3
AliasesPX3
GeneCards (Weizmann)PANX3
Ensembl hg19 (Hinxton)ENSG00000154143 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154143 [Gene_View]  chr11:124611557-124620355 [Contig_View]  PANX3 [Vega]
ICGC DataPortalENSG00000154143
TCGA cBioPortalPANX3
AceView (NCBI)PANX3
Genatlas (Paris)PANX3
WikiGenes116337
SOURCE (Princeton)PANX3
Genetics Home Reference (NIH)PANX3
Genomic and cartography
GoldenPath hg38 (UCSC)PANX3  -     chr11:124611557-124620355 +  11q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PANX3  -     11q24.2   [Description]    (hg19-Feb_2009)
EnsemblPANX3 - 11q24.2 [CytoView hg19]  PANX3 - 11q24.2 [CytoView hg38]
Mapping of homologs : NCBIPANX3 [Mapview hg19]  PANX3 [Mapview hg38]
OMIM608422   
Gene and transcription
Genbank (Entrez)AA456140 AF406650 BC152944
RefSeq transcript (Entrez)NM_052959
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PANX3
Cluster EST : UnigeneHs.99235 [ NCBI ]
CGAP (NCI)Hs.99235
Alternative Splicing GalleryENSG00000154143
Gene ExpressionPANX3 [ NCBI-GEO ]   PANX3 [ EBI - ARRAY_EXPRESS ]   PANX3 [ SEEK ]   PANX3 [ MEM ]
Gene Expression Viewer (FireBrowse)PANX3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116337
GTEX Portal (Tissue expression)PANX3
Human Protein AtlasENSG00000154143-PANX3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QZ0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96QZ0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96QZ0
Splice isoforms : SwissVarQ96QZ0
PhosPhoSitePlusQ96QZ0
Domaine pattern : Prosite (Expaxy)PANNEXIN (PS51013)   
Domains : Interpro (EBI)Innexin   
Domain families : Pfam (Sanger)Innexin (PF00876)   
Domain families : Pfam (NCBI)pfam00876   
Conserved Domain (NCBI)PANX3
DMDM Disease mutations116337
Blocks (Seattle)PANX3
SuperfamilyQ96QZ0
Human Protein Atlas [tissue]ENSG00000154143-PANX3 [tissue]
Peptide AtlasQ96QZ0
HPRD16334
IPIIPI00045156   
Protein Interaction databases
DIP (DOE-UCLA)Q96QZ0
IntAct (EBI)Q96QZ0
FunCoupENSG00000154143
BioGRIDPANX3
STRING (EMBL)PANX3
ZODIACPANX3
Ontologies - Pathways
QuickGOQ96QZ0
Ontology : AmiGOplasma membrane  gap junction  cation transport  cell-cell signaling  endomembrane system  integral component of membrane  wide pore channel activity  protein hexamerization  gap junction hemi-channel activity  transmembrane transport  
Ontology : EGO-EBIplasma membrane  gap junction  cation transport  cell-cell signaling  endomembrane system  integral component of membrane  wide pore channel activity  protein hexamerization  gap junction hemi-channel activity  transmembrane transport  
NDEx NetworkPANX3
Atlas of Cancer Signalling NetworkPANX3
Wikipedia pathwaysPANX3
Orthology - Evolution
OrthoDB116337
GeneTree (enSembl)ENSG00000154143
Phylogenetic Trees/Animal Genes : TreeFamPANX3
HOVERGENQ96QZ0
HOGENOMQ96QZ0
Homologs : HomoloGenePANX3
Homology/Alignments : Family Browser (UCSC)PANX3
Gene fusions - Rearrangements
Tumor Fusion PortalPANX3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPANX3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PANX3
dbVarPANX3
ClinVarPANX3
1000_GenomesPANX3 
Exome Variant ServerPANX3
ExAC (Exome Aggregation Consortium)ENSG00000154143
GNOMAD BrowserENSG00000154143
Genetic variants : HAPMAP116337
Genomic Variants (DGV)PANX3 [DGVbeta]
DECIPHERPANX3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPANX3 
Mutations
ICGC Data PortalPANX3 
TCGA Data PortalPANX3 
Broad Tumor PortalPANX3
OASIS PortalPANX3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPANX3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPANX3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PANX3
DgiDB (Drug Gene Interaction Database)PANX3
DoCM (Curated mutations)PANX3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PANX3 (select a term)
intoGenPANX3
Cancer3DPANX3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608422   
Orphanet
DisGeNETPANX3
MedgenPANX3
Genetic Testing Registry PANX3
NextProtQ96QZ0 [Medical]
TSGene116337
GENETestsPANX3
Target ValidationPANX3
Huge Navigator PANX3 [HugePedia]
snp3D : Map Gene to Disease116337
BioCentury BCIQPANX3
ClinGenPANX3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116337
Chemical/Pharm GKB GenePA134920643
Clinical trialPANX3
Miscellaneous
canSAR (ICR)PANX3 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePANX3
EVEXPANX3
GoPubMedPANX3
iHOPPANX3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:27:43 CET 2017

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