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PAOX (polyamine oxidase)

Identity

Alias_namespolyamine oxidase (exo-N4-amino)
Alias_symbol (synonym)PAO
Other alias
HGNC (Hugo) PAOX
LocusID (NCBI) 196743
Atlas_Id 46509
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 133379237 and ends at 133391696 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ZNF346 (5q35.2) / PAOX (10q26.3)ZNF346 5q35.2 / PAOX 10q26.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PAOX   20837
Cards
Entrez_Gene (NCBI)PAOX  196743  polyamine oxidase
AliasesPAO
GeneCards (Weizmann)PAOX
Ensembl hg19 (Hinxton)ENSG00000148832 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148832 [Gene_View]  chr10:133379237-133391696 [Contig_View]  PAOX [Vega]
ICGC DataPortalENSG00000148832
TCGA cBioPortalPAOX
AceView (NCBI)PAOX
Genatlas (Paris)PAOX
WikiGenes196743
SOURCE (Princeton)PAOX
Genetics Home Reference (NIH)PAOX
Genomic and cartography
GoldenPath hg38 (UCSC)PAOX  -     chr10:133379237-133391696 +  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAOX  -     10q26.3   [Description]    (hg19-Feb_2009)
EnsemblPAOX - 10q26.3 [CytoView hg19]  PAOX - 10q26.3 [CytoView hg38]
Mapping of homologs : NCBIPAOX [Mapview hg19]  PAOX [Mapview hg38]
OMIM615853   
Gene and transcription
Genbank (Entrez)AA280165 AF226657 AF312698 AK124186 AK128001
RefSeq transcript (Entrez)NM_152911 NM_207125 NM_207126 NM_207127 NM_207128 NM_207129
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAOX
Cluster EST : UnigeneHs.501578 [ NCBI ]
CGAP (NCI)Hs.501578
Alternative Splicing GalleryENSG00000148832
Gene ExpressionPAOX [ NCBI-GEO ]   PAOX [ EBI - ARRAY_EXPRESS ]   PAOX [ SEEK ]   PAOX [ MEM ]
Gene Expression Viewer (FireBrowse)PAOX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)196743
GTEX Portal (Tissue expression)PAOX
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6QHF9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6QHF9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6QHF9
Splice isoforms : SwissVarQ6QHF9
Catalytic activity : Enzyme1.5.3.13 [ Enzyme-Expasy ]   1.5.3.131.5.3.13 [ IntEnz-EBI ]   1.5.3.13 [ BRENDA ]   1.5.3.13 [ KEGG ]   
PhosPhoSitePlusQ6QHF9
Domains : Interpro (EBI)Amino_oxidase    FAD/NAD-binding_dom   
Domain families : Pfam (Sanger)Amino_oxidase (PF01593)   
Domain families : Pfam (NCBI)pfam01593   
Conserved Domain (NCBI)PAOX
DMDM Disease mutations196743
Blocks (Seattle)PAOX
SuperfamilyQ6QHF9
Human Protein AtlasENSG00000148832
Peptide AtlasQ6QHF9
HPRD10136
IPIIPI00456650   IPI00456669   IPI00456670   IPI00166789   IPI00456651   IPI00418231   IPI00827966   IPI00410386   IPI00456652   IPI00856013   IPI00745346   IPI00952623   IPI00952694   IPI01018773   IPI00978326   IPI01008874   
Protein Interaction databases
DIP (DOE-UCLA)Q6QHF9
IntAct (EBI)Q6QHF9
FunCoupENSG00000148832
BioGRIDPAOX
STRING (EMBL)PAOX
ZODIACPAOX
Ontologies - Pathways
QuickGOQ6QHF9
Ontology : AmiGOreceptor binding  peroxisomal matrix  polyamine biosynthetic process  putrescine biosynthetic process  putrescine catabolic process  spermidine catabolic process  spermine catabolic process  polyamine oxidase activity  N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity  spermine:oxygen oxidoreductase (spermidine-forming) activity  spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity  N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity  N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity  oxidation-reduction process  positive regulation of spermidine biosynthetic process  
Ontology : EGO-EBIreceptor binding  peroxisomal matrix  polyamine biosynthetic process  putrescine biosynthetic process  putrescine catabolic process  spermidine catabolic process  spermine catabolic process  polyamine oxidase activity  N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity  spermine:oxygen oxidoreductase (spermidine-forming) activity  spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity  N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity  N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity  oxidation-reduction process  positive regulation of spermidine biosynthetic process  
Pathways : KEGGPeroxisome   
NDEx NetworkPAOX
Atlas of Cancer Signalling NetworkPAOX
Wikipedia pathwaysPAOX
Orthology - Evolution
OrthoDB196743
GeneTree (enSembl)ENSG00000148832
Phylogenetic Trees/Animal Genes : TreeFamPAOX
HOVERGENQ6QHF9
HOGENOMQ6QHF9
Homologs : HomoloGenePAOX
Homology/Alignments : Family Browser (UCSC)PAOX
Gene fusions - Rearrangements
Fusion : MitelmanZNF346/PAOX [5q35.2/10q26.3]  [t(5;10)(q35;q26)]  
Fusion: TCGAZNF346 5q35.2 PAOX 10q26.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAOX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAOX
dbVarPAOX
ClinVarPAOX
1000_GenomesPAOX 
Exome Variant ServerPAOX
ExAC (Exome Aggregation Consortium)PAOX (select the gene name)
Genetic variants : HAPMAP196743
Genomic Variants (DGV)PAOX [DGVbeta]
DECIPHERPAOX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAOX 
Mutations
ICGC Data PortalPAOX 
TCGA Data PortalPAOX 
Broad Tumor PortalPAOX
OASIS PortalPAOX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAOX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPAOX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAOX
DgiDB (Drug Gene Interaction Database)PAOX
DoCM (Curated mutations)PAOX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAOX (select a term)
intoGenPAOX
Cancer3DPAOX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615853   
Orphanet
MedgenPAOX
Genetic Testing Registry PAOX
NextProtQ6QHF9 [Medical]
TSGene196743
GENETestsPAOX
Target ValidationPAOX
Huge Navigator PAOX [HugePedia]
snp3D : Map Gene to Disease196743
BioCentury BCIQPAOX
ClinGenPAOX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD196743
Chemical/Pharm GKB GenePA134907695
Clinical trialPAOX
Miscellaneous
canSAR (ICR)PAOX (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAOX
EVEXPAOX
GoPubMedPAOX
iHOPPAOX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:48:27 CEST 2017

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