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PAPD5 (poly(A) RNA polymerase D5, non-canonical)

Identity

Alias_namesPAP associated domain containing 5
Alias_symbol (synonym)TRF4-2
Other alias
HGNC (Hugo) PAPD5
LocusID (NCBI) 64282
Atlas_Id 53652
Location 16q12.1  [Link to chromosome band 16q12]
Location_base_pair Starts at 50152918 and ends at 50235308 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CYLD (16q12.1) / PAPD5 (16q12.1)PAPD5 (16q12.1) / PAPD5 (16q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PAPD5   30758
Cards
Entrez_Gene (NCBI)PAPD5  64282  poly(A) RNA polymerase D5, non-canonical
AliasesTRF4-2
GeneCards (Weizmann)PAPD5
Ensembl hg19 (Hinxton)ENSG00000121274 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121274 [Gene_View]  chr16:50152918-50235308 [Contig_View]  PAPD5 [Vega]
ICGC DataPortalENSG00000121274
TCGA cBioPortalPAPD5
AceView (NCBI)PAPD5
Genatlas (Paris)PAPD5
WikiGenes64282
SOURCE (Princeton)PAPD5
Genetics Home Reference (NIH)PAPD5
Genomic and cartography
GoldenPath hg38 (UCSC)PAPD5  -     chr16:50152918-50235308 +  16q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAPD5  -     16q12.1   [Description]    (hg19-Feb_2009)
EnsemblPAPD5 - 16q12.1 [CytoView hg19]  PAPD5 - 16q12.1 [CytoView hg38]
Mapping of homologs : NCBIPAPD5 [Mapview hg19]  PAPD5 [Mapview hg38]
OMIM605540   
Gene and transcription
Genbank (Entrez)AF089897 AK001141 AK097589 AK098806 AK223410
RefSeq transcript (Entrez)NM_001040284 NM_001040285 NM_022447
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAPD5
Cluster EST : UnigeneHs.514342 [ NCBI ]
CGAP (NCI)Hs.514342
Alternative Splicing GalleryENSG00000121274
Gene ExpressionPAPD5 [ NCBI-GEO ]   PAPD5 [ EBI - ARRAY_EXPRESS ]   PAPD5 [ SEEK ]   PAPD5 [ MEM ]
Gene Expression Viewer (FireBrowse)PAPD5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64282
GTEX Portal (Tissue expression)PAPD5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NDF8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NDF8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NDF8
Splice isoforms : SwissVarQ8NDF8
Catalytic activity : Enzyme2.7.7.19 [ Enzyme-Expasy ]   2.7.7.192.7.7.19 [ IntEnz-EBI ]   2.7.7.19 [ BRENDA ]   2.7.7.19 [ KEGG ]   
PhosPhoSitePlusQ8NDF8
Domains : Interpro (EBI)PAP_assoc    Polymerase_NTP_transf_dom   
Domain families : Pfam (Sanger)NTP_transf_2 (PF01909)    PAP_assoc (PF03828)   
Domain families : Pfam (NCBI)pfam01909    pfam03828   
Conserved Domain (NCBI)PAPD5
DMDM Disease mutations64282
Blocks (Seattle)PAPD5
SuperfamilyQ8NDF8
Human Protein AtlasENSG00000121274
Peptide AtlasQ8NDF8
HPRD16119
IPIIPI01011361   IPI00383794   IPI00550722   IPI00940660   IPI00643763   IPI00301922   
Protein Interaction databases
DIP (DOE-UCLA)Q8NDF8
IntAct (EBI)Q8NDF8
FunCoupENSG00000121274
BioGRIDPAPD5
STRING (EMBL)PAPD5
ZODIACPAPD5
Ontologies - Pathways
QuickGOQ8NDF8
Ontology : AmiGODNA binding  RNA binding  DNA-directed DNA polymerase activity  polynucleotide adenylyltransferase activity  cellular_component  nucleolus  cytoplasm  rRNA processing  mRNA processing  cell cycle  negative regulation of telomere maintenance via telomerase  ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process  metal ion binding  cell division  telomerase RNA binding  histone mRNA catabolic process  DNA biosynthetic process  
Ontology : EGO-EBIDNA binding  RNA binding  DNA-directed DNA polymerase activity  polynucleotide adenylyltransferase activity  cellular_component  nucleolus  cytoplasm  rRNA processing  mRNA processing  cell cycle  negative regulation of telomere maintenance via telomerase  ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process  metal ion binding  cell division  telomerase RNA binding  histone mRNA catabolic process  DNA biosynthetic process  
NDEx NetworkPAPD5
Atlas of Cancer Signalling NetworkPAPD5
Wikipedia pathwaysPAPD5
Orthology - Evolution
OrthoDB64282
GeneTree (enSembl)ENSG00000121274
Phylogenetic Trees/Animal Genes : TreeFamPAPD5
HOVERGENQ8NDF8
HOGENOMQ8NDF8
Homologs : HomoloGenePAPD5
Homology/Alignments : Family Browser (UCSC)PAPD5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAPD5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAPD5
dbVarPAPD5
ClinVarPAPD5
1000_GenomesPAPD5 
Exome Variant ServerPAPD5
ExAC (Exome Aggregation Consortium)PAPD5 (select the gene name)
Genetic variants : HAPMAP64282
Genomic Variants (DGV)PAPD5 [DGVbeta]
DECIPHERPAPD5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAPD5 
Mutations
ICGC Data PortalPAPD5 
TCGA Data PortalPAPD5 
Broad Tumor PortalPAPD5
OASIS PortalPAPD5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAPD5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPAPD5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAPD5
DgiDB (Drug Gene Interaction Database)PAPD5
DoCM (Curated mutations)PAPD5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAPD5 (select a term)
intoGenPAPD5
Cancer3DPAPD5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605540   
Orphanet
MedgenPAPD5
Genetic Testing Registry PAPD5
NextProtQ8NDF8 [Medical]
TSGene64282
GENETestsPAPD5
Target ValidationPAPD5
Huge Navigator PAPD5 [HugePedia]
snp3D : Map Gene to Disease64282
BioCentury BCIQPAPD5
ClinGenPAPD5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64282
Chemical/Pharm GKB GenePA134949693
Clinical trialPAPD5
Miscellaneous
canSAR (ICR)PAPD5 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAPD5
EVEXPAPD5
GoPubMedPAPD5
iHOPPAPD5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:23:42 CEST 2017

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