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PAPD7 (poly(A) RNA polymerase D7, non-canonical)

Identity

Alias_namesPOLS
polymerase (DNA directed) sigma
PAP associated domain containing 7
Alias_symbol (synonym)POLK
TRF4
LAK-1
TRF4-1
Other aliasLAK1
TRF41
TUTASE5
HGNC (Hugo) PAPD7
LocusID (NCBI) 11044
Atlas_Id 51320
Location 5p15.31  [Link to chromosome band 5p15]
Location_base_pair Starts at 6714605 and ends at 6757048 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PAPD7 (5p15.31) / NDUFS6 (5p15.33)PAPD7 (5p15.31) / PAPD7 (5p15.31)PAPD7 (5p15.31) / RAF1 (3p25.2)
PAPD7 (5p15.31) / SRD5A1 (5p15.31)PAPD7 (5p15.31) / SSR2 (1q22)STARD3NL (7p14.1) / PAPD7 (5p15.31)
PAPD7 5p15.31 / SRD5A1 5p15.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PAPD7   16705
Cards
Entrez_Gene (NCBI)PAPD7  11044  poly(A) RNA polymerase D7, non-canonical
AliasesLAK-1; LAK1; POLK; POLS; 
TRF4; TRF4-1; TRF41; TUTASE5
GeneCards (Weizmann)PAPD7
Ensembl hg19 (Hinxton)ENSG00000112941 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112941 [Gene_View]  chr5:6714605-6757048 [Contig_View]  PAPD7 [Vega]
ICGC DataPortalENSG00000112941
TCGA cBioPortalPAPD7
AceView (NCBI)PAPD7
Genatlas (Paris)PAPD7
WikiGenes11044
SOURCE (Princeton)PAPD7
Genetics Home Reference (NIH)PAPD7
Genomic and cartography
GoldenPath hg38 (UCSC)PAPD7  -     chr5:6714605-6757048 +  5p15.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAPD7  -     5p15.31   [Description]    (hg19-Feb_2009)
EnsemblPAPD7 - 5p15.31 [CytoView hg19]  PAPD7 - 5p15.31 [CytoView hg38]
Mapping of homologs : NCBIPAPD7 [Mapview hg19]  PAPD7 [Mapview hg38]
OMIM605198   
Gene and transcription
Genbank (Entrez)AB005754 AF089896 AI871781 AK289857 AK303516
RefSeq transcript (Entrez)NM_001171805 NM_001171806 NM_006999
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAPD7
Cluster EST : UnigeneHs.481542 [ NCBI ]
CGAP (NCI)Hs.481542
Alternative Splicing GalleryENSG00000112941
Gene ExpressionPAPD7 [ NCBI-GEO ]   PAPD7 [ EBI - ARRAY_EXPRESS ]   PAPD7 [ SEEK ]   PAPD7 [ MEM ]
Gene Expression Viewer (FireBrowse)PAPD7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11044
GTEX Portal (Tissue expression)PAPD7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5XG87   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5XG87  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5XG87
Splice isoforms : SwissVarQ5XG87
Catalytic activity : Enzyme2.7.7.19 [ Enzyme-Expasy ]   2.7.7.192.7.7.19 [ IntEnz-EBI ]   2.7.7.19 [ BRENDA ]   2.7.7.19 [ KEGG ]   
PhosPhoSitePlusQ5XG87
Domains : Interpro (EBI)PAP_assoc    Polymerase_NTP_transf_dom   
Domain families : Pfam (Sanger)NTP_transf_2 (PF01909)    PAP_assoc (PF03828)   
Domain families : Pfam (NCBI)pfam01909    pfam03828   
Conserved Domain (NCBI)PAPD7
DMDM Disease mutations11044
Blocks (Seattle)PAPD7
SuperfamilyQ5XG87
Human Protein AtlasENSG00000112941
Peptide AtlasQ5XG87
HPRD09239
IPIIPI00418630   IPI00955501   IPI00955495   
Protein Interaction databases
DIP (DOE-UCLA)Q5XG87
IntAct (EBI)Q5XG87
FunCoupENSG00000112941
BioGRIDPAPD7
STRING (EMBL)PAPD7
ZODIACPAPD7
Ontologies - Pathways
QuickGOQ5XG87
Ontology : AmiGOpolynucleotide adenylyltransferase activity  ATP binding  nucleus  nucleoplasm  Golgi apparatus  double-strand break repair  mRNA processing  sister chromatid cohesion  mitotic chromosome condensation  nuclear membrane  response to drug  SMC family protein binding  metal ion binding  
Ontology : EGO-EBIpolynucleotide adenylyltransferase activity  ATP binding  nucleus  nucleoplasm  Golgi apparatus  double-strand break repair  mRNA processing  sister chromatid cohesion  mitotic chromosome condensation  nuclear membrane  response to drug  SMC family protein binding  metal ion binding  
Pathways : KEGGRNA degradation   
NDEx NetworkPAPD7
Atlas of Cancer Signalling NetworkPAPD7
Wikipedia pathwaysPAPD7
Orthology - Evolution
OrthoDB11044
GeneTree (enSembl)ENSG00000112941
Phylogenetic Trees/Animal Genes : TreeFamPAPD7
HOVERGENQ5XG87
HOGENOMQ5XG87
Homologs : HomoloGenePAPD7
Homology/Alignments : Family Browser (UCSC)PAPD7
Gene fusions - Rearrangements
Fusion : MitelmanPAPD7/SRD5A1 [5p15.31/5p15.31]  
Fusion: TCGAPAPD7 5p15.31 SRD5A1 5p15.31 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAPD7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAPD7
dbVarPAPD7
ClinVarPAPD7
1000_GenomesPAPD7 
Exome Variant ServerPAPD7
ExAC (Exome Aggregation Consortium)PAPD7 (select the gene name)
Genetic variants : HAPMAP11044
Genomic Variants (DGV)PAPD7 [DGVbeta]
DECIPHERPAPD7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAPD7 
Mutations
ICGC Data PortalPAPD7 
TCGA Data PortalPAPD7 
Broad Tumor PortalPAPD7
OASIS PortalPAPD7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAPD7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPAPD7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAPD7
DgiDB (Drug Gene Interaction Database)PAPD7
DoCM (Curated mutations)PAPD7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAPD7 (select a term)
intoGenPAPD7
Cancer3DPAPD7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605198   
Orphanet
MedgenPAPD7
Genetic Testing Registry PAPD7
NextProtQ5XG87 [Medical]
TSGene11044
GENETestsPAPD7
Target ValidationPAPD7
Huge Navigator PAPD7 [HugePedia]
snp3D : Map Gene to Disease11044
BioCentury BCIQPAPD7
ClinGenPAPD7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11044
Chemical/Pharm GKB GenePA33523
Clinical trialPAPD7
Miscellaneous
canSAR (ICR)PAPD7 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAPD7
EVEXPAPD7
GoPubMedPAPD7
iHOPPAPD7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:10:02 CEST 2017

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