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PAPOLG (poly(A) polymerase gamma)

Identity

Alias_symbol (synonym)FLJ12972
Other alias-
HGNC (Hugo) PAPOLG
LocusID (NCBI) 64895
Atlas_Id 71655
Location 2p16.1  [Link to chromosome band 2p16]
Location_base_pair Starts at 60756230 and ends at 60802086 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PAPOLG (2p16.1) / ABCA12 (2q35)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PAPOLG   14982
Cards
Entrez_Gene (NCBI)PAPOLG  64895  poly(A) polymerase gamma
Aliases
GeneCards (Weizmann)PAPOLG
Ensembl hg19 (Hinxton)ENSG00000115421 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115421 [Gene_View]  chr2:60756230-60802086 [Contig_View]  PAPOLG [Vega]
ICGC DataPortalENSG00000115421
TCGA cBioPortalPAPOLG
AceView (NCBI)PAPOLG
Genatlas (Paris)PAPOLG
WikiGenes64895
SOURCE (Princeton)PAPOLG
Genetics Home Reference (NIH)PAPOLG
Genomic and cartography
GoldenPath hg38 (UCSC)PAPOLG  -     chr2:60756230-60802086 +  2p16.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAPOLG  -     2p16.1   [Description]    (hg19-Feb_2009)
EnsemblPAPOLG - 2p16.1 [CytoView hg19]  PAPOLG - 2p16.1 [CytoView hg38]
Mapping of homologs : NCBIPAPOLG [Mapview hg19]  PAPOLG [Mapview hg38]
OMIM616865   
Gene and transcription
Genbank (Entrez)AB209304 AF312211 AI419423 AJ308101 AK021867
RefSeq transcript (Entrez)NM_022894
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAPOLG
Cluster EST : UnigeneHs.387471 [ NCBI ]
CGAP (NCI)Hs.387471
Alternative Splicing GalleryENSG00000115421
Gene ExpressionPAPOLG [ NCBI-GEO ]   PAPOLG [ EBI - ARRAY_EXPRESS ]   PAPOLG [ SEEK ]   PAPOLG [ MEM ]
Gene Expression Viewer (FireBrowse)PAPOLG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64895
GTEX Portal (Tissue expression)PAPOLG
Human Protein AtlasENSG00000115421-PAPOLG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BWT3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BWT3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BWT3
Splice isoforms : SwissVarQ9BWT3
Catalytic activity : Enzyme2.7.7.19 [ Enzyme-Expasy ]   2.7.7.192.7.7.19 [ IntEnz-EBI ]   2.7.7.19 [ BRENDA ]   2.7.7.19 [ KEGG ]   
PhosPhoSitePlusQ9BWT3
Domains : Interpro (EBI)NuclTrfase_I_C    PolA_pol_cen_dom    PolA_pol_RNA-bd_dom    PolyA_polymerase    Polymerase_NTP_transf_dom   
Domain families : Pfam (Sanger)NTP_transf_2 (PF01909)    PAP_central (PF04928)    PAP_RNA-bind (PF04926)   
Domain families : Pfam (NCBI)pfam01909    pfam04928    pfam04926   
Conserved Domain (NCBI)PAPOLG
DMDM Disease mutations64895
Blocks (Seattle)PAPOLG
PDB (SRS)4LT6   
PDB (PDBSum)4LT6   
PDB (IMB)4LT6   
PDB (RSDB)4LT6   
Structural Biology KnowledgeBase4LT6   
SCOP (Structural Classification of Proteins)4LT6   
CATH (Classification of proteins structures)4LT6   
SuperfamilyQ9BWT3
Human Protein Atlas [tissue]ENSG00000115421-PAPOLG [tissue]
Peptide AtlasQ9BWT3
HPRD11420
IPIIPI00304442   IPI00555821   IPI00893537   IPI00893718   
Protein Interaction databases
DIP (DOE-UCLA)Q9BWT3
IntAct (EBI)Q9BWT3
FunCoupENSG00000115421
BioGRIDPAPOLG
STRING (EMBL)PAPOLG
ZODIACPAPOLG
Ontologies - Pathways
QuickGOQ9BWT3
Ontology : AmiGORNA binding  polynucleotide adenylyltransferase activity  ATP binding  nucleus  nucleoplasm  cytosol  mRNA polyadenylation  membrane  nuclear body  RNA polyadenylation  metal ion binding  
Ontology : EGO-EBIRNA binding  polynucleotide adenylyltransferase activity  ATP binding  nucleus  nucleoplasm  cytosol  mRNA polyadenylation  membrane  nuclear body  RNA polyadenylation  metal ion binding  
Pathways : KEGGmRNA surveillance pathway   
NDEx NetworkPAPOLG
Atlas of Cancer Signalling NetworkPAPOLG
Wikipedia pathwaysPAPOLG
Orthology - Evolution
OrthoDB64895
GeneTree (enSembl)ENSG00000115421
Phylogenetic Trees/Animal Genes : TreeFamPAPOLG
HOVERGENQ9BWT3
HOGENOMQ9BWT3
Homologs : HomoloGenePAPOLG
Homology/Alignments : Family Browser (UCSC)PAPOLG
Gene fusions - Rearrangements
Tumor Fusion PortalPAPOLG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAPOLG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAPOLG
dbVarPAPOLG
ClinVarPAPOLG
1000_GenomesPAPOLG 
Exome Variant ServerPAPOLG
ExAC (Exome Aggregation Consortium)ENSG00000115421
GNOMAD BrowserENSG00000115421
Genetic variants : HAPMAP64895
Genomic Variants (DGV)PAPOLG [DGVbeta]
DECIPHERPAPOLG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAPOLG 
Mutations
ICGC Data PortalPAPOLG 
TCGA Data PortalPAPOLG 
Broad Tumor PortalPAPOLG
OASIS PortalPAPOLG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAPOLG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPAPOLG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAPOLG
DgiDB (Drug Gene Interaction Database)PAPOLG
DoCM (Curated mutations)PAPOLG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAPOLG (select a term)
intoGenPAPOLG
Cancer3DPAPOLG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616865   
Orphanet
DisGeNETPAPOLG
MedgenPAPOLG
Genetic Testing Registry PAPOLG
NextProtQ9BWT3 [Medical]
TSGene64895
GENETestsPAPOLG
Target ValidationPAPOLG
Huge Navigator PAPOLG [HugePedia]
snp3D : Map Gene to Disease64895
BioCentury BCIQPAPOLG
ClinGenPAPOLG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64895
Chemical/Pharm GKB GenePA32934
Clinical trialPAPOLG
Miscellaneous
canSAR (ICR)PAPOLG (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAPOLG
EVEXPAPOLG
GoPubMedPAPOLG
iHOPPAPOLG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:05:59 CET 2017

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