Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1)

Identity

Alias_symbol (synonym)ATPSK1
PAPSS
Other aliasSK1
HGNC (Hugo) PAPSS1
LocusID (NCBI) 9061
Atlas_Id 41638
Location 4q25  [Link to chromosome band 4q25]
Location_base_pair Starts at 107613666 and ends at 107720263 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PAPSS1 (4q25) / PAPSS1 (4q25)PAPSS1 (4q25) / PKNOX1 (21q22.3)PAPSS1 (4q25) / RAB13 (1q21.3)
PNKD (2q35) / PAPSS1 (4q25)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PAPSS1   8603
Cards
Entrez_Gene (NCBI)PAPSS1  9061  3'-phosphoadenosine 5'-phosphosulfate synthase 1
AliasesATPSK1; PAPSS; SK1
GeneCards (Weizmann)PAPSS1
Ensembl hg19 (Hinxton)ENSG00000138801 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138801 [Gene_View]  chr4:107613666-107720263 [Contig_View]  PAPSS1 [Vega]
ICGC DataPortalENSG00000138801
TCGA cBioPortalPAPSS1
AceView (NCBI)PAPSS1
Genatlas (Paris)PAPSS1
WikiGenes9061
SOURCE (Princeton)PAPSS1
Genetics Home Reference (NIH)PAPSS1
Genomic and cartography
GoldenPath hg38 (UCSC)PAPSS1  -     chr4:107613666-107720263 -  4q25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAPSS1  -     4q25   [Description]    (hg19-Feb_2009)
EnsemblPAPSS1 - 4q25 [CytoView hg19]  PAPSS1 - 4q25 [CytoView hg38]
Mapping of homologs : NCBIPAPSS1 [Mapview hg19]  PAPSS1 [Mapview hg38]
OMIM603262   
Gene and transcription
Genbank (Entrez)AF016496 AF033026 AF105227 AK292774 AK297981
RefSeq transcript (Entrez)NM_005443
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAPSS1
Cluster EST : UnigeneHs.368610 [ NCBI ]
CGAP (NCI)Hs.368610
Alternative Splicing GalleryENSG00000138801
Gene ExpressionPAPSS1 [ NCBI-GEO ]   PAPSS1 [ EBI - ARRAY_EXPRESS ]   PAPSS1 [ SEEK ]   PAPSS1 [ MEM ]
Gene Expression Viewer (FireBrowse)PAPSS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9061
GTEX Portal (Tissue expression)PAPSS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43252   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43252  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43252
Splice isoforms : SwissVarO43252
PhosPhoSitePlusO43252
Domains : Interpro (EBI)APS_kinase    ATP-Sase_PUA-like_dom    P-loop_NTPase    PUA-like_domain    Rossmann-like_a/b/a_fold    Sulfurylase_cat_dom    Sulphate_adenylyltransferase   
Domain families : Pfam (Sanger)ATP-sulfurylase (PF01747)    PUA_2 (PF14306)   
Domain families : Pfam (NCBI)pfam01747    pfam14306   
Conserved Domain (NCBI)PAPSS1
DMDM Disease mutations9061
Blocks (Seattle)PAPSS1
PDB (SRS)1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
PDB (PDBSum)1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
PDB (IMB)1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
PDB (RSDB)1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
Structural Biology KnowledgeBase1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
SCOP (Structural Classification of Proteins)1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
CATH (Classification of proteins structures)1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
SuperfamilyO43252
Human Protein AtlasENSG00000138801
Peptide AtlasO43252
HPRD09132
IPIIPI00011619   
Protein Interaction databases
DIP (DOE-UCLA)O43252
IntAct (EBI)O43252
FunCoupENSG00000138801
BioGRIDPAPSS1
STRING (EMBL)PAPSS1
ZODIACPAPSS1
Ontologies - Pathways
QuickGOO43252
Ontology : AmiGOsulfate assimilation  sulfate assimilation  skeletal system development  adenylylsulfate kinase activity  adenylylsulfate kinase activity  sulfate adenylyltransferase (ATP) activity  sulfate adenylyltransferase (ATP) activity  sulfate adenylyltransferase (ATP) activity  ATP binding  cytosol  phosphorylation  nucleotidyltransferase activity  protein homodimerization activity  3'-phosphoadenosine 5'-phosphosulfate biosynthetic process  3'-phosphoadenosine 5'-phosphosulfate biosynthetic process  
Ontology : EGO-EBIsulfate assimilation  sulfate assimilation  skeletal system development  adenylylsulfate kinase activity  adenylylsulfate kinase activity  sulfate adenylyltransferase (ATP) activity  sulfate adenylyltransferase (ATP) activity  sulfate adenylyltransferase (ATP) activity  ATP binding  cytosol  phosphorylation  nucleotidyltransferase activity  protein homodimerization activity  3'-phosphoadenosine 5'-phosphosulfate biosynthetic process  3'-phosphoadenosine 5'-phosphosulfate biosynthetic process  
Pathways : KEGGPurine metabolism    Selenocompound metabolism    Sulfur metabolism   
NDEx NetworkPAPSS1
Atlas of Cancer Signalling NetworkPAPSS1
Wikipedia pathwaysPAPSS1
Orthology - Evolution
OrthoDB9061
GeneTree (enSembl)ENSG00000138801
Phylogenetic Trees/Animal Genes : TreeFamPAPSS1
HOVERGENO43252
HOGENOMO43252
Homologs : HomoloGenePAPSS1
Homology/Alignments : Family Browser (UCSC)PAPSS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAPSS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAPSS1
dbVarPAPSS1
ClinVarPAPSS1
1000_GenomesPAPSS1 
Exome Variant ServerPAPSS1
ExAC (Exome Aggregation Consortium)PAPSS1 (select the gene name)
Genetic variants : HAPMAP9061
Genomic Variants (DGV)PAPSS1 [DGVbeta]
DECIPHERPAPSS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAPSS1 
Mutations
ICGC Data PortalPAPSS1 
TCGA Data PortalPAPSS1 
Broad Tumor PortalPAPSS1
OASIS PortalPAPSS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPAPSS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPAPSS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAPSS1
DgiDB (Drug Gene Interaction Database)PAPSS1
DoCM (Curated mutations)PAPSS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAPSS1 (select a term)
intoGenPAPSS1
Cancer3DPAPSS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603262   
Orphanet
MedgenPAPSS1
Genetic Testing Registry PAPSS1
NextProtO43252 [Medical]
TSGene9061
GENETestsPAPSS1
Target ValidationPAPSS1
Huge Navigator PAPSS1 [HugePedia]
snp3D : Map Gene to Disease9061
BioCentury BCIQPAPSS1
ClinGenPAPSS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9061
Chemical/Pharm GKB GenePA384
Clinical trialPAPSS1
Miscellaneous
canSAR (ICR)PAPSS1 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAPSS1
EVEXPAPSS1
GoPubMedPAPSS1
iHOPPAPSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:23:43 CEST 2017

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