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PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1)

Identity

Other namesATPSK1
PAPSS
SK1
HGNC (Hugo) PAPSS1
Location 4q25
Location_base_pair Starts at 108754271 and ends at 108860868 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PAPSS1   8603
Entrez_Gene (NCBI)PAPSS1  9061  3'-phosphoadenosine 5'-phosphosulfate synthase 1
Cards
GeneCards (Weizmann)PAPSS1
Ensembl (Hinxton)ENSG00000138801 [Gene_View]  PAPSS1 [Vega]
AceView (NCBI)PAPSS1
Genatlas (Paris)PAPSS1
euGene (Indiana)9061
SOURCE (Stanford)NM_005443
Gene Expression (Array Express) ENSG00000138801
Genomic and cartography
GoldenPath (UCSC)PAPSS1  -  4q25   chr4:108754271-108860868 -  4q25   [Description]    (hg18-March_2006)
EnsemblPAPSS1 - 4q25 [CytoView]
Mapping of homologs : NCBIPAPSS1 [Mapview]
OMIM603262   
Gene and transcription
Gene : Genbank (Entrez)AF016496 AF033026 AF105227 AK292774 AK297981
Reference sequence (RefSeq transcript) :SRSNM_005443
Reference transcript : EntrezNM_005443
RefSeq genomic : SRSAC_000047 AC_000136 NC_000004 NT_016354 NW_001838915 NW_922162
RefSeq genomic : EntrezAC_000047 AC_000136 NC_000004 NT_016354 NW_001838915 NW_922162
Consensus coding sequences : CCDS NCBIPAPSS1
Cluster EST : UnigeneHs.368610 [ SRS ] Hs.368610 [ NCBI ]
Alternative Splicing : Fast-db (Paris)8238
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtO43252 (SRS) O43252 (Expasy) O43252 (Uniprot)
With graphics : InterProO43252
Splice isoforms : VarSplice FASTAO43252(VarSplice FASTA)
Domains : Interpro (SRS)APS_kinase_C    PUA-like    Rossmann-like_a/b/a_fold    Sulphate_adenylyltransferase   
Domains : Interpro (EBI)APS_kinase_C    PUA-like    Rossmann-like_a/b/a_fold    Sulphate_adenylyltransferase   
Related proteins : CluSTrO43252
Domain families : Pfam SRSAPS_kinase (PF01583)    ATP-sulfurylase (PF01747)   
Domain families : Pfam SangerAPS_kinase (PF01583)    ATP-sulfurylase (PF01747)   
Domain families : Pfam NCBIpfam01583    pfam01747   
Blocks (Seattle)O43252
Crystal structure of protein : PDB SRS1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
Crystal structure of protein : PDBSum1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
Crystal structure of protein : IMB1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
Crystal structure of protein : PDB RSDB1X6V    1XJQ    1XNJ    2OFW    2OFX    2PEY    2PEZ    2QJF   
HPRD09132
Protein Interaction databases
DIP (DOE-UCLA)O43252
IntAct (EBI)O43252
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIPAPSS1
SNP : GeneSNP UtahPAPSS1
SNP : HGBasePAPSS1
Genetic variants : HAPMAPPAPSS1
Somatic Mutations in Cancer : COSMICPAPSS1 
Mutations and Diseases : HGMDPAPSS1
Hereditary diseases : OMIM603262   
Hereditary diseases : GENETests603262   
Diseases : Genetic AssociationPAPSS1
General knowledge
Homologs : HomoloGenePAPSS1
Homology/Alignments : Family Browser UCSCPAPSS1
Phylogenetic Trees/Animal Genes : TreeFamPAPSS1
Catalytic activity : Enzyme2.7.7.4 [ Enzyme-Expasy ]   2.7.7.4 [ Enzyme-SRS ]   2.7.7.4 [ IntEnz-EBI ]   2.7.7.4 [ BRENDA ]   2.7.7.4 [ KEGG ]   
Chemical/Protein Interactions : CTD9061
Keywords Ontology : AmiGOsulfate assimilation  nucleotide binding  skeletal system development  adenylylsulfate kinase activity  sulfate adenylyltransferase (ATP) activity  ATP binding  nucleotidyltransferase activity  3'-phosphoadenosine 5'-phosphosulfate biosynthetic process  
Keywords Ontology : EGO-EBIsulfate assimilation  nucleotide binding  skeletal system development  adenylylsulfate kinase activity  sulfate adenylyltransferase (ATP) activity  ATP binding  nucleotidyltransferase activity  3'-phosphoadenosine 5'-phosphosulfate biosynthetic process  
Pathways : BIOCARTA
Pathways : KEGGPurine metabolismSelenoamino acid metabolismSulfur metabolism
Other databases
Probes
Probes : ImagenesPAPSS1 Related clones (RZPD - Berlin)
Literature
PubMed20 Pubmed reference(s) in Entrez
PubGenePAPSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

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indexed on : Sat Feb 27 10:30:58 CET 2010
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