Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PARD6G (par-6 family cell polarity regulator gamma)

Identity

Alias_namespar-6 (partitioning defective 6, C.elegans) homolog gamma
par-6 partitioning defective 6 homolog gamma (C. elegans)
Alias_symbol (synonym)PAR-6G
PAR6gamma
Other alias
HGNC (Hugo) PARD6G
LocusID (NCBI) 84552
Atlas_Id 54529
Location 18q23  [Link to chromosome band 18q23]
Location_base_pair Starts at 77915117 and ends at 78005397 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADNP2 (18q23) / PARD6G (18q23)KDM4C (9p24.1) / PARD6G (18q23)PARD6G (18q23) / CHST1 (11p11.2)
PARD6G (18q23) / LDLRAD4 (18p11.21)PARD6G (18q23) / RFTN2 (2q33.1)ADNP2 18q23 / PARD6G 18q23
PARD6G 18q23 / CHST1 11p11.2PARD6G 18q23 / RFTN2 2q33.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PARD6G   16076
Cards
Entrez_Gene (NCBI)PARD6G  84552  par-6 family cell polarity regulator gamma
AliasesPAR-6G; PAR6gamma
GeneCards (Weizmann)PARD6G
Ensembl hg19 (Hinxton)ENSG00000178184 [Gene_View]  chr18:77915117-78005397 [Contig_View]  PARD6G [Vega]
Ensembl hg38 (Hinxton)ENSG00000178184 [Gene_View]  chr18:77915117-78005397 [Contig_View]  PARD6G [Vega]
ICGC DataPortalENSG00000178184
TCGA cBioPortalPARD6G
AceView (NCBI)PARD6G
Genatlas (Paris)PARD6G
WikiGenes84552
SOURCE (Princeton)PARD6G
Genetics Home Reference (NIH)PARD6G
Genomic and cartography
GoldenPath hg19 (UCSC)PARD6G  -     chr18:77915117-78005397 -  18q23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PARD6G  -     18q23   [Description]    (hg38-Dec_2013)
EnsemblPARD6G - 18q23 [CytoView hg19]  PARD6G - 18q23 [CytoView hg38]
Mapping of homologs : NCBIPARD6G [Mapview hg19]  PARD6G [Mapview hg38]
OMIM608976   
Gene and transcription
Genbank (Entrez)AA502508 AB043635 AB044556 AB178535 AB178536
RefSeq transcript (Entrez)NM_032510
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929411
Consensus coding sequences : CCDS (NCBI)PARD6G
Cluster EST : UnigeneHs.654920 [ NCBI ]
CGAP (NCI)Hs.654920
Alternative Splicing GalleryENSG00000178184
Gene ExpressionPARD6G [ NCBI-GEO ]   PARD6G [ EBI - ARRAY_EXPRESS ]   PARD6G [ SEEK ]   PARD6G [ MEM ]
Gene Expression Viewer (FireBrowse)PARD6G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84552
GTEX Portal (Tissue expression)PARD6G
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYG4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYG4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYG4
Splice isoforms : SwissVarQ9BYG4
PhosPhoSitePlusQ9BYG4
Domaine pattern : Prosite (Expaxy)PB1 (PS51745)    PDZ (PS50106)   
Domains : Interpro (EBI)PB1_dom    PDZ   
Domain families : Pfam (Sanger)PB1 (PF00564)    PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00564    pfam00595   
Domain families : Smart (EMBL)PB1 (SM00666)  PDZ (SM00228)  
Conserved Domain (NCBI)PARD6G
DMDM Disease mutations84552
Blocks (Seattle)PARD6G
SuperfamilyQ9BYG4
Human Protein AtlasENSG00000178184
Peptide AtlasQ9BYG4
HPRD10138
IPIIPI00032555   IPI01019079   IPI00385586   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYG4
IntAct (EBI)Q9BYG4
FunCoupENSG00000178184
BioGRIDPARD6G
STRING (EMBL)PARD6G
ZODIACPARD6G
Ontologies - Pathways
QuickGOQ9BYG4
Ontology : AmiGOprotein binding  cytosol  plasma membrane  bicellular tight junction  cell cycle  cell division  bicellular tight junction assembly  
Ontology : EGO-EBIprotein binding  cytosol  plasma membrane  bicellular tight junction  cell cycle  cell division  bicellular tight junction assembly  
Pathways : KEGGRap1 signaling pathway    Endocytosis    Hippo signaling pathway    Tight junction   
NDEx NetworkPARD6G
Atlas of Cancer Signalling NetworkPARD6G
Wikipedia pathwaysPARD6G
Orthology - Evolution
OrthoDB84552
GeneTree (enSembl)ENSG00000178184
Phylogenetic Trees/Animal Genes : TreeFamPARD6G
HOVERGENQ9BYG4
HOGENOMQ9BYG4
Homologs : HomoloGenePARD6G
Homology/Alignments : Family Browser (UCSC)PARD6G
Gene fusions - Rearrangements
Fusion : MitelmanPARD6G/CHST1 [18q23/11p11.2]  
Fusion : MitelmanPARD6G/LDLRAD4 [18q23/18p11.21]  [t(18;18)(p11;q23)]  
Fusion : MitelmanPARD6G/RFTN2 [18q23/2q33.1]  [t(2;18)(q33;q23)]  
Fusion: TCGAADNP2 18q23 PARD6G 18q23 LGG
Fusion: TCGAPARD6G 18q23 CHST1 11p11.2 HNSC
Fusion: TCGAPARD6G 18q23 RFTN2 2q33.1 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARD6G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARD6G
dbVarPARD6G
ClinVarPARD6G
1000_GenomesPARD6G 
Exome Variant ServerPARD6G
ExAC (Exome Aggregation Consortium)PARD6G (select the gene name)
Genetic variants : HAPMAP84552
Genomic Variants (DGV)PARD6G [DGVbeta]
DECIPHER (Syndromes)18:77915117-78005397  ENSG00000178184
CONAN: Copy Number AnalysisPARD6G 
Mutations
ICGC Data PortalPARD6G 
TCGA Data PortalPARD6G 
Broad Tumor PortalPARD6G
OASIS PortalPARD6G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARD6G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPARD6G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PARD6G
DgiDB (Drug Gene Interaction Database)PARD6G
DoCM (Curated mutations)PARD6G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PARD6G (select a term)
intoGenPARD6G
Cancer3DPARD6G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608976   
Orphanet
MedgenPARD6G
Genetic Testing Registry PARD6G
NextProtQ9BYG4 [Medical]
TSGene84552
GENETestsPARD6G
Huge Navigator PARD6G [HugePedia]
snp3D : Map Gene to Disease84552
BioCentury BCIQPARD6G
ClinGenPARD6G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84552
Chemical/Pharm GKB GenePA32939
Clinical trialPARD6G
Miscellaneous
canSAR (ICR)PARD6G (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePARD6G
EVEXPARD6G
GoPubMedPARD6G
iHOPPARD6G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:13:32 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.