Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8505
MIM: 603501
HGNC: 8605
Ensembl: ENSG00000227345
Variants:
dbSNP: 8505
ClinVar: 8505
TCGA: ENSG00000227345
COSMIC: PARG
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000227345 | ENST00000402038 | Q86W56 |
| ENSG00000227345 | ENST00000610922 | A0A087WXI6 |
| ENSG00000227345 | ENST00000614063 | A0A087WX07 |
| ENSG00000227345 | ENST00000616448 | Q86W56 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37429965 | 2024 | PARG Promotes Esophagus Cancer Cell Metastasis by Activation of the Wnt/β-Catenin Pathway. | 0 |
| 37429965 | 2024 | PARG Promotes Esophagus Cancer Cell Metastasis by Activation of the Wnt/β-Catenin Pathway. | 0 |
| 37858678 | 2023 | O-GlcNAc has crosstalk with ADP-ribosylation via PARG. | 4 |
| 37858678 | 2023 | O-GlcNAc has crosstalk with ADP-ribosylation via PARG. | 4 |
| 36076593 | 2022 | Upregulation of PARG in prostate cancer cells suppresses their malignant behavior and downregulates tumor-promoting genes. | 2 |
| 36076593 | 2022 | Upregulation of PARG in prostate cancer cells suppresses their malignant behavior and downregulates tumor-promoting genes. | 2 |
| 33649309 | 2021 | Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose). | 33 |
| 34019811 | 2021 | Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. | 44 |
| 33649309 | 2021 | Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose). | 33 |
| 34019811 | 2021 | Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. | 44 |
| 32439163 | 2020 | PARG has a robust endo-glycohydrolase activity that releases protein-free poly(ADP-ribose) chains. | 13 |
| 33046907 | 2020 | Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. | 24 |
| 32439163 | 2020 | PARG has a robust endo-glycohydrolase activity that releases protein-free poly(ADP-ribose) chains. | 13 |
| 33046907 | 2020 | Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. | 24 |
| 30459355 | 2019 | Oncogenic activity of poly (ADP-ribose) glycohydrolase. | 19 |
Citation
Dessen P
PARG (poly(ADP-ribose) glycohydrolase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43674/parg
