PARP11 (poly(ADP-ribose) polymerase family member 11)

2014-11-01 Affiliation

Identity

HGNC

PARP11

LOCATION

12p13.32

LOCUSID

57097

ALIAS

ARTD11,C12orf6,MIB006

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 57097
MIM: 616706
HGNC: 1186
Ensembl: ENSG00000111224

Variants:

dbSNP: 57097
ClinVar: 57097
TCGA: ENSG00000111224
COSMIC: PARP11

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000111224	ENST00000228820	Q9NR21
ENSG00000111224	ENST00000416739	Q9NR21
ENSG00000111224	ENST00000427057	Q9NR21
ENSG00000111224	ENST00000447133	Q9NR21
ENSG00000111224	ENST00000450737	F5H8L8
ENSG00000111224	ENST00000453942	G3V0I3
ENSG00000111224	ENST00000458162	F8WFA3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

PharmGKB

Entity ID	Name	Type	Evidence	Association	PK	PD	PMIDs
PA447321	Depressive Disorder, Major	Disease	ClinicalAnnotation	associated		PD
PA452229	antidepressants	Chemical	ClinicalAnnotation	associated		PD

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62

Citation

Dessen P

PARP11 (poly(ADP-ribose) polymerase family member 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71668/parp11