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PARP14 (poly(ADP-ribose) polymerase family member 14)

Identity

Alias_symbol (synonym)KIAA1268
pART8
Other aliasARTD8
BAL2
PARP-14
HGNC (Hugo) PARP14
LocusID (NCBI) 54625
Atlas_Id 52482
Location 3q21.1  [Link to chromosome band 3q21]
Location_base_pair Starts at 122680825 and ends at 122730840 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADAM12 (10q26.2) / PARP14 (3q21.1)ITGB5 (3q21.2) / PARP14 (3q21.1)OGFOD1 (16q12.2) / PARP14 (3q21.1)
PARP14 (3q21.1) / HPS5 (11p15.1)PARP14 (3q21.1) / PARP14 (3q21.1)PARP14 (3q21.1) / SLC44A5 (1p31.1)
PARP14 (3q21.1) / TASP1 (20p12.1)PARP14 (3q21.1) / TFE3 (Xp11.23)ITGB5 3q21.2 / PARP14 3q21.1
PARP14 3q21.1 / TASP1 20p12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PARP14   29232
Cards
Entrez_Gene (NCBI)PARP14  54625  poly(ADP-ribose) polymerase family member 14
AliasesARTD8; BAL2; PARP-14; pART8
GeneCards (Weizmann)PARP14
Ensembl hg19 (Hinxton)ENSG00000173193 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173193 [Gene_View]  chr3:122680825-122730840 [Contig_View]  PARP14 [Vega]
ICGC DataPortalENSG00000173193
TCGA cBioPortalPARP14
AceView (NCBI)PARP14
Genatlas (Paris)PARP14
WikiGenes54625
SOURCE (Princeton)PARP14
Genetics Home Reference (NIH)PARP14
Genomic and cartography
GoldenPath hg38 (UCSC)PARP14  -     chr3:122680825-122730840 +  3q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PARP14  -     3q21.1   [Description]    (hg19-Feb_2009)
EnsemblPARP14 - 3q21.1 [CytoView hg19]  PARP14 - 3q21.1 [CytoView hg38]
Mapping of homologs : NCBIPARP14 [Mapview hg19]  PARP14 [Mapview hg38]
OMIM610028   
Gene and transcription
Genbank (Entrez)AA890511 AB033094 AK001770 AK022542 AK026003
RefSeq transcript (Entrez)NM_017554
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PARP14
Cluster EST : UnigeneHs.518203 [ NCBI ]
CGAP (NCI)Hs.518203
Alternative Splicing GalleryENSG00000173193
Gene ExpressionPARP14 [ NCBI-GEO ]   PARP14 [ EBI - ARRAY_EXPRESS ]   PARP14 [ SEEK ]   PARP14 [ MEM ]
Gene Expression Viewer (FireBrowse)PARP14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54625
GTEX Portal (Tissue expression)PARP14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ460N5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ460N5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ460N5
Splice isoforms : SwissVarQ460N5
Catalytic activity : Enzyme2.4.2.30 [ Enzyme-Expasy ]   2.4.2.302.4.2.30 [ IntEnz-EBI ]   2.4.2.30 [ BRENDA ]   2.4.2.30 [ KEGG ]   
PhosPhoSitePlusQ460N5
Domaine pattern : Prosite (Expaxy)MACRO (PS51154)    PARP_CATALYTIC (PS51059)    WWE (PS50918)   
Domains : Interpro (EBI)Macro_dom    Poly(ADP-ribose)pol_cat_dom    WWE-dom   
Domain families : Pfam (Sanger)Macro (PF01661)    PARP (PF00644)   
Domain families : Pfam (NCBI)pfam01661    pfam00644   
Domain families : Smart (EMBL)A1pp (SM00506)  
Conserved Domain (NCBI)PARP14
DMDM Disease mutations54625
Blocks (Seattle)PARP14
PDB (SRS)3GOY    3Q6Z    3Q71    3SE2    3SMI    3SMJ    3VFQ    4ABK    4ABL    4D86    4F1L    4F1Q    4PY4    5LXP    5LYH   
PDB (PDBSum)3GOY    3Q6Z    3Q71    3SE2    3SMI    3SMJ    3VFQ    4ABK    4ABL    4D86    4F1L    4F1Q    4PY4    5LXP    5LYH   
PDB (IMB)3GOY    3Q6Z    3Q71    3SE2    3SMI    3SMJ    3VFQ    4ABK    4ABL    4D86    4F1L    4F1Q    4PY4    5LXP    5LYH   
PDB (RSDB)3GOY    3Q6Z    3Q71    3SE2    3SMI    3SMJ    3VFQ    4ABK    4ABL    4D86    4F1L    4F1Q    4PY4    5LXP    5LYH   
Structural Biology KnowledgeBase3GOY    3Q6Z    3Q71    3SE2    3SMI    3SMJ    3VFQ    4ABK    4ABL    4D86    4F1L    4F1Q    4PY4    5LXP    5LYH   
SCOP (Structural Classification of Proteins)3GOY    3Q6Z    3Q71    3SE2    3SMI    3SMJ    3VFQ    4ABK    4ABL    4D86    4F1L    4F1Q    4PY4    5LXP    5LYH   
CATH (Classification of proteins structures)3GOY    3Q6Z    3Q71    3SE2    3SMI    3SMJ    3VFQ    4ABK    4ABL    4D86    4F1L    4F1Q    4PY4    5LXP    5LYH   
SuperfamilyQ460N5
Human Protein AtlasENSG00000173193
Peptide AtlasQ460N5
HPRD11421
IPIIPI00783216   IPI00783883   IPI00783683   IPI00784370   IPI00291215   IPI00334349   
Protein Interaction databases
DIP (DOE-UCLA)Q460N5
IntAct (EBI)Q460N5
FunCoupENSG00000173193
BioGRIDPARP14
STRING (EMBL)PARP14
ZODIACPARP14
Ontologies - Pathways
QuickGOQ460N5
Ontology : AmiGORNA binding  NAD+ ADP-ribosyltransferase activity  nucleus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  membrane  
Ontology : EGO-EBIRNA binding  NAD+ ADP-ribosyltransferase activity  nucleus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  membrane  
NDEx NetworkPARP14
Atlas of Cancer Signalling NetworkPARP14
Wikipedia pathwaysPARP14
Orthology - Evolution
OrthoDB54625
GeneTree (enSembl)ENSG00000173193
Phylogenetic Trees/Animal Genes : TreeFamPARP14
HOVERGENQ460N5
HOGENOMQ460N5
Homologs : HomoloGenePARP14
Homology/Alignments : Family Browser (UCSC)PARP14
Gene fusions - Rearrangements
Fusion : MitelmanITGB5/PARP14 [3q21.2/3q21.1]  [t(3;3)(q21;q21)]  
Fusion : MitelmanPARP14/TASP1 [3q21.1/20p12.1]  [t(3;20)(q21;p12)]  
Fusion : MitelmanPARP14/TFE3 [3q21.1/Xp11.23]  [t(X;3)(p11;q21)]  
Fusion: TCGAITGB5 3q21.2 PARP14 3q21.1 BRCA
Fusion: TCGAPARP14 3q21.1 TASP1 20p12.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARP14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARP14
dbVarPARP14
ClinVarPARP14
1000_GenomesPARP14 
Exome Variant ServerPARP14
ExAC (Exome Aggregation Consortium)PARP14 (select the gene name)
Genetic variants : HAPMAP54625
Genomic Variants (DGV)PARP14 [DGVbeta]
DECIPHERPARP14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPARP14 
Mutations
ICGC Data PortalPARP14 
TCGA Data PortalPARP14 
Broad Tumor PortalPARP14
OASIS PortalPARP14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARP14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPARP14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PARP14
DgiDB (Drug Gene Interaction Database)PARP14
DoCM (Curated mutations)PARP14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PARP14 (select a term)
intoGenPARP14
Cancer3DPARP14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610028   
Orphanet
MedgenPARP14
Genetic Testing Registry PARP14
NextProtQ460N5 [Medical]
TSGene54625
GENETestsPARP14
Target ValidationPARP14
Huge Navigator PARP14 [HugePedia]
snp3D : Map Gene to Disease54625
BioCentury BCIQPARP14
ClinGenPARP14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54625
Chemical/Pharm GKB GenePA134861585
Clinical trialPARP14
Miscellaneous
canSAR (ICR)PARP14 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePARP14
EVEXPARP14
GoPubMedPARP14
iHOPPARP14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:23:47 CEST 2017

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