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PARP16 (poly(ADP-ribose) polymerase family member 16)

Identity

Alias_namesC15orf30
chromosome 15 open reading frame 30
Alias_symbol (synonym)FLJ20509
FLJ25281
pART15
Other aliasARTD15
HGNC (Hugo) PARP16
LocusID (NCBI) 54956
Atlas_Id 71671
Location 15q22.31  [Link to chromosome band 15q22]
Location_base_pair Starts at 65258094 and ends at 65286843 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD276 (15q24.1) / PARP16 (15q22.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PARP16   26040
Cards
Entrez_Gene (NCBI)PARP16  54956  poly(ADP-ribose) polymerase family member 16
AliasesARTD15; C15orf30; pART15
GeneCards (Weizmann)PARP16
Ensembl hg19 (Hinxton)ENSG00000138617 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138617 [Gene_View]  chr15:65258094-65286843 [Contig_View]  PARP16 [Vega]
ICGC DataPortalENSG00000138617
TCGA cBioPortalPARP16
AceView (NCBI)PARP16
Genatlas (Paris)PARP16
WikiGenes54956
SOURCE (Princeton)PARP16
Genetics Home Reference (NIH)PARP16
Genomic and cartography
GoldenPath hg38 (UCSC)PARP16  -     chr15:65258094-65286843 -  15q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PARP16  -     15q22.31   [Description]    (hg19-Feb_2009)
EnsemblPARP16 - 15q22.31 [CytoView hg19]  PARP16 - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBIPARP16 [Mapview hg19]  PARP16 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK000516 AK058010 BC006389 BC031074 DA110379
RefSeq transcript (Entrez)NM_001316943 NM_001316944 NM_017851
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PARP16
Cluster EST : UnigeneHs.30634 [ NCBI ]
CGAP (NCI)Hs.30634
Alternative Splicing GalleryENSG00000138617
Gene ExpressionPARP16 [ NCBI-GEO ]   PARP16 [ EBI - ARRAY_EXPRESS ]   PARP16 [ SEEK ]   PARP16 [ MEM ]
Gene Expression Viewer (FireBrowse)PARP16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54956
GTEX Portal (Tissue expression)PARP16
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5Y8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5Y8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5Y8
Splice isoforms : SwissVarQ8N5Y8
PhosPhoSitePlusQ8N5Y8
Domaine pattern : Prosite (Expaxy)PARP_CATALYTIC (PS51059)   
Domains : Interpro (EBI)Poly(ADP-ribose)pol_cat_dom   
Domain families : Pfam (Sanger)PARP (PF00644)   
Domain families : Pfam (NCBI)pfam00644   
Conserved Domain (NCBI)PARP16
DMDM Disease mutations54956
Blocks (Seattle)PARP16
PDB (SRS)4F0D   
PDB (PDBSum)4F0D   
PDB (IMB)4F0D   
PDB (RSDB)4F0D   
Structural Biology KnowledgeBase4F0D   
SCOP (Structural Classification of Proteins)4F0D   
CATH (Classification of proteins structures)4F0D   
SuperfamilyQ8N5Y8
Human Protein AtlasENSG00000138617
Peptide AtlasQ8N5Y8
HPRD07919
IPIIPI00794653   IPI00016479   IPI00297151   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5Y8
IntAct (EBI)Q8N5Y8
FunCoupENSG00000138617
BioGRIDPARP16
STRING (EMBL)PARP16
ZODIACPARP16
Ontologies - Pathways
QuickGOQ8N5Y8
Ontology : AmiGONAD+ ADP-ribosyltransferase activity  NAD+ ADP-ribosyltransferase activity  protein binding  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  cytosol  protein ADP-ribosylation  activation of signaling protein activity involved in unfolded protein response  membrane  integral component of membrane  kinase binding  endoplasmic reticulum unfolded protein response  NAD biosynthesis via nicotinamide riboside salvage pathway  protein serine/threonine kinase activator activity  negative regulation of cell death  protein auto-ADP-ribosylation  endoplasmic reticulum tubular network  positive regulation of protein serine/threonine kinase activity  
Ontology : EGO-EBINAD+ ADP-ribosyltransferase activity  NAD+ ADP-ribosyltransferase activity  protein binding  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  cytosol  protein ADP-ribosylation  activation of signaling protein activity involved in unfolded protein response  membrane  integral component of membrane  kinase binding  endoplasmic reticulum unfolded protein response  NAD biosynthesis via nicotinamide riboside salvage pathway  protein serine/threonine kinase activator activity  negative regulation of cell death  protein auto-ADP-ribosylation  endoplasmic reticulum tubular network  positive regulation of protein serine/threonine kinase activity  
NDEx NetworkPARP16
Atlas of Cancer Signalling NetworkPARP16
Wikipedia pathwaysPARP16
Orthology - Evolution
OrthoDB54956
GeneTree (enSembl)ENSG00000138617
Phylogenetic Trees/Animal Genes : TreeFamPARP16
HOVERGENQ8N5Y8
HOGENOMQ8N5Y8
Homologs : HomoloGenePARP16
Homology/Alignments : Family Browser (UCSC)PARP16
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARP16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARP16
dbVarPARP16
ClinVarPARP16
1000_GenomesPARP16 
Exome Variant ServerPARP16
ExAC (Exome Aggregation Consortium)PARP16 (select the gene name)
Genetic variants : HAPMAP54956
Genomic Variants (DGV)PARP16 [DGVbeta]
DECIPHERPARP16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPARP16 
Mutations
ICGC Data PortalPARP16 
TCGA Data PortalPARP16 
Broad Tumor PortalPARP16
OASIS PortalPARP16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARP16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPARP16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PARP16
DgiDB (Drug Gene Interaction Database)PARP16
DoCM (Curated mutations)PARP16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PARP16 (select a term)
intoGenPARP16
Cancer3DPARP16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPARP16
Genetic Testing Registry PARP16
NextProtQ8N5Y8 [Medical]
TSGene54956
GENETestsPARP16
Huge Navigator PARP16 [HugePedia]
snp3D : Map Gene to Disease54956
BioCentury BCIQPARP16
ClinGenPARP16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54956
Chemical/Pharm GKB GenePA134984504
Clinical trialPARP16
Miscellaneous
canSAR (ICR)PARP16 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePARP16
EVEXPARP16
GoPubMedPARP16
iHOPPARP16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 11:47:48 CEST 2017

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