PARP4 (poly (ADP-ribose) polymerase family, member 4)

Identity

Other names	ADPRTL1
	PARPL
	PH5P
	VAULT3
	VPARP
	VWA5C
	p193
HGNC	PARP4
Location	13q11
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PARP4   271
Entrez_Gene	PARP4  143  poly (ADP-ribose) polymerase family, member 4
	Cards
GeneCards	PARP4
Ensembl	PARP4 [Search_View]   ENSG00000102699 [Gene_View]
Genatlas	PARP4
GeneLynx	PARP4
eGenome	PARP4
euGene	143
	Genomic and cartography
GoldenPath	PARP4  -  13q11   chr13:23893069-23984948 -  13q12.12   [Description]    (hg18-March_2006)
Ensembl	PARP4 - 13q12.12 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PARP4
	Gene and transcription
Genbank	AF057160 [ ENTREZ ]
Genbank	AF158255 [ ENTREZ ]
Genbank	BC017815 [ ENTREZ ]
Genbank	BC167791 [ ENTREZ ]
Genbank	BX479127 [ ENTREZ ]
RefSeq	NM_006437 [ SRS ]    NM_006437 [ ENTREZ ]
RefSeq	AC_000056 [ SRS ]    AC_000056 [ ENTREZ ]
RefSeq	AC_000145 [ SRS ]    AC_000145 [ ENTREZ ]
RefSeq	NC_000013 [ SRS ]    NC_000013 [ ENTREZ ]
RefSeq	NT_024524 [ SRS ]    NT_024524 [ ENTREZ ]
RefSeq	NW_001838070 [ SRS ]    NW_001838070 [ ENTREZ ]
RefSeq	NW_925473 [ SRS ]    NW_925473 [ ENTREZ ]
AceView	PARP4 AceView - NCBI
Unigene	Hs.591227 [ SRS ]    Hs.591227 [ NCBI ]     HS591227 [ spliceNest ]
Fast-db	1092 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q5QNZ9 [ SRS]    Q5QNZ9 [ EXPASY ]     Q5QNZ9 [ INTERPRO ]     Q5QNZ9 [ UNIPROT ]
Prosite	PS50172 BRCT [ SRS ]    PS50172 BRCT [ Expasy ]
Prosite	PS51060 PARP_ALPHA_HD [ SRS ]    PS51060 PARP_ALPHA_HD [ Expasy ]
Prosite	PS51059 PARP_CATALYTIC [ SRS ]    PS51059 PARP_CATALYTIC [ Expasy ]
Prosite	PS50234 VWFA [ SRS ]    PS50234 VWFA [ Expasy ]
Interpro	IPR001357 BRCT [ SRS ]    IPR001357 BRCT [ EBI ]
Interpro	IPR012317 PARP_catalytic [ SRS ]    IPR012317 PARP_catalytic [ EBI ]
Interpro	IPR004102 PARP_reg [ SRS ]    IPR004102 PARP_reg [ EBI ]
Interpro	IPR013694 VIT [ SRS ]    IPR013694 VIT [ EBI ]
Interpro	IPR006587 VIT_met [ SRS ]    IPR006587 VIT_met [ EBI ]
Interpro	IPR002035 VWF_A [ SRS ]    IPR002035 VWF_A [ EBI ]
CluSTr	Q5QNZ9
Pfam	PF00533 BRCT [ SRS ]    PF00533 BRCT [ Sanger ]    pfam00533 [ NCBI-CDD ]
Pfam	PF00644 PARP [ SRS ]    PF00644 PARP [ Sanger ]    pfam00644 [ NCBI-CDD ]
Pfam	PF08487 VIT [ SRS ]    PF08487 VIT [ Sanger ]    pfam08487 [ NCBI-CDD ]
Pfam	PF00092 VWA [ SRS ]    PF00092 VWA [ Sanger ]    pfam00092 [ NCBI-CDD ]
Smart	SM00292 BRCT [EMBL]
Smart	SM00609 VIT [EMBL]
Smart	SM00327 VWA [EMBL]
Blocks	Q5QNZ9
HPRD	09598
	Protein Interaction databases
DIP	Q5QNZ9
IntAct	Q5QNZ9
	Polymorphism : SNP, mutations, diseases
OMIM	607519    [ map ]
GENECLINICS	607519
SNP	PARP4 [dbSNP-NCBI]
SNP	NM_006437 [SNP-NCI]
SNP	PARP4 [GeneSNPs - Utah]  PARP4] [HGBASE - SRS]
HAPMAP	PARP4 [HAPMAP]
HGMD	PARP4
	General knowledge
Family Browser	PARP4 [UCSC Family Browser]
SOURCE	NM_006437
SMD	Hs.591227
SAGE	Hs.591227
GO	DNA binding [Amigo]  DNA binding
GO	NAD+ ADP-ribosyltransferase activity [Amigo]  NAD+ ADP-ribosyltransferase activity
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	DNA repair [Amigo]  DNA repair
GO	protein modification process [Amigo]  protein modification process
GO	protein amino acid ADP-ribosylation [Amigo]  protein amino acid ADP-ribosylation
GO	transport [Amigo]  transport
GO	inflammatory response [Amigo]  inflammatory response
GO	cell death [Amigo]  cell death
GO	transferase activity, transferring glycosyl groups [Amigo]  transferase activity, transferring glycosyl groups
GO	enzyme binding [Amigo]  enzyme binding
GO	ribonucleoprotein complex [Amigo]  ribonucleoprotein complex
GO	response to drug [Amigo]  response to drug
PubGene	PARP4
TreeFam	PARP4
CTD	143 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PARP4 Related clones (RZPD - Berlin)
	PubMed
PubMed	20 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:23:43 2008