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PARP6 (poly(ADP-ribose) polymerase family member 6)

Identity

Alias_symbol (synonym)pART17
Other aliasARTD17
PARP-6-B1
PARP-6-C
HGNC (Hugo) PARP6
LocusID (NCBI) 56965
Atlas_Id 53270
Location 15q23  [Link to chromosome band 15q23]
Location_base_pair Starts at 72241181 and ends at 72272575 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RNF149 (2q11.2) / PARP6 (15q23)SPAG9 (17q21.33) / PARP6 (15q23)UBE2V1 (20q13.13) / PARP6 (15q23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PARP6   26921
Cards
Entrez_Gene (NCBI)PARP6  56965  poly(ADP-ribose) polymerase family member 6
AliasesARTD17; PARP-6-B1; PARP-6-C; pART17
GeneCards (Weizmann)PARP6
Ensembl hg19 (Hinxton)ENSG00000137817 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137817 [Gene_View]  chr15:72241181-72272575 [Contig_View]  PARP6 [Vega]
ICGC DataPortalENSG00000137817
TCGA cBioPortalPARP6
AceView (NCBI)PARP6
Genatlas (Paris)PARP6
WikiGenes56965
SOURCE (Princeton)PARP6
Genetics Home Reference (NIH)PARP6
Genomic and cartography
GoldenPath hg38 (UCSC)PARP6  -     chr15:72241181-72272575 -  15q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PARP6  -     15q23   [Description]    (hg19-Feb_2009)
EnsemblPARP6 - 15q23 [CytoView hg19]  PARP6 - 15q23 [CytoView hg38]
Mapping of homologs : NCBIPARP6 [Mapview hg19]  PARP6 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB499727 AB499728 AK021790 AK022547 AK024703
RefSeq transcript (Entrez)NM_001323515 NM_001323516 NM_001323519 NM_001323521 NM_001323522 NM_001323523 NM_001323524 NM_001323525 NM_001323526 NM_001323528 NM_001323530 NM_001323531 NM_001323532 NM_020213 NM_020214
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PARP6
Cluster EST : UnigeneHs.270244 [ NCBI ]
CGAP (NCI)Hs.270244
Alternative Splicing GalleryENSG00000137817
Gene ExpressionPARP6 [ NCBI-GEO ]   PARP6 [ EBI - ARRAY_EXPRESS ]   PARP6 [ SEEK ]   PARP6 [ MEM ]
Gene Expression Viewer (FireBrowse)PARP6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56965
GTEX Portal (Tissue expression)PARP6
Human Protein AtlasENSG00000137817-PARP6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2NL67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2NL67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2NL67
Splice isoforms : SwissVarQ2NL67
Catalytic activity : Enzyme2.4.2.30 [ Enzyme-Expasy ]   2.4.2.302.4.2.30 [ IntEnz-EBI ]   2.4.2.30 [ BRENDA ]   2.4.2.30 [ KEGG ]   
PhosPhoSitePlusQ2NL67
Domaine pattern : Prosite (Expaxy)PARP_CATALYTIC (PS51059)   
Domains : Interpro (EBI)Poly(ADP-ribose)pol_cat_dom   
Domain families : Pfam (Sanger)PARP (PF00644)   
Domain families : Pfam (NCBI)pfam00644   
Conserved Domain (NCBI)PARP6
DMDM Disease mutations56965
Blocks (Seattle)PARP6
SuperfamilyQ2NL67
Human Protein Atlas [tissue]ENSG00000137817-PARP6 [tissue]
Peptide AtlasQ2NL67
HPRD15102
IPIIPI00156933   IPI00796582   IPI00790056   IPI00795447   IPI01015768   IPI00941899   IPI00183978   
Protein Interaction databases
DIP (DOE-UCLA)Q2NL67
IntAct (EBI)Q2NL67
FunCoupENSG00000137817
BioGRIDPARP6
STRING (EMBL)PARP6
ZODIACPARP6
Ontologies - Pathways
QuickGOQ2NL67
Ontology : AmiGONAD+ ADP-ribosyltransferase activity  
Ontology : EGO-EBINAD+ ADP-ribosyltransferase activity  
NDEx NetworkPARP6
Atlas of Cancer Signalling NetworkPARP6
Wikipedia pathwaysPARP6
Orthology - Evolution
OrthoDB56965
GeneTree (enSembl)ENSG00000137817
Phylogenetic Trees/Animal Genes : TreeFamPARP6
HOVERGENQ2NL67
HOGENOMQ2NL67
Homologs : HomoloGenePARP6
Homology/Alignments : Family Browser (UCSC)PARP6
Gene fusions - Rearrangements
Tumor Fusion PortalPARP6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARP6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARP6
dbVarPARP6
ClinVarPARP6
1000_GenomesPARP6 
Exome Variant ServerPARP6
ExAC (Exome Aggregation Consortium)ENSG00000137817
GNOMAD BrowserENSG00000137817
Genetic variants : HAPMAP56965
Genomic Variants (DGV)PARP6 [DGVbeta]
DECIPHERPARP6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPARP6 
Mutations
ICGC Data PortalPARP6 
TCGA Data PortalPARP6 
Broad Tumor PortalPARP6
OASIS PortalPARP6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARP6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPARP6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PARP6
DgiDB (Drug Gene Interaction Database)PARP6
DoCM (Curated mutations)PARP6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PARP6 (select a term)
intoGenPARP6
Cancer3DPARP6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPARP6
MedgenPARP6
Genetic Testing Registry PARP6
NextProtQ2NL67 [Medical]
TSGene56965
GENETestsPARP6
Target ValidationPARP6
Huge Navigator PARP6 [HugePedia]
snp3D : Map Gene to Disease56965
BioCentury BCIQPARP6
ClinGenPARP6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56965
Chemical/Pharm GKB GenePA134900863
Clinical trialPARP6
Miscellaneous
canSAR (ICR)PARP6 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePARP6
EVEXPARP6
GoPubMedPARP6
iHOPPARP6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:27:49 CET 2017

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