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PARP8 (poly(ADP-ribose) polymerase family member 8)

Identity

Alias (NCBI)ARTD16
pART16
HGNC (Hugo) PARP8
HGNC Alias symbFLJ21308
pART16
LocusID (NCBI) 79668
Atlas_Id 71672
Location 5q11.1  [Link to chromosome band 5q11]
Location_base_pair Starts at 50666637 and ends at 50846519 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PARP8 (5q11.1) / LDAH (2p24.1)PARP8 (5q11.1) / PARP8 (5q11.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PARP8   26124
Cards
Entrez_Gene (NCBI)PARP8    poly(ADP-ribose) polymerase family member 8
AliasesARTD16; pART16
GeneCards (Weizmann)PARP8
Ensembl hg19 (Hinxton)ENSG00000151883 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151883 [Gene_View]  ENSG00000151883 [Sequence]  chr5:50666637-50846519 [Contig_View]  PARP8 [Vega]
ICGC DataPortalENSG00000151883
TCGA cBioPortalPARP8
AceView (NCBI)PARP8
Genatlas (Paris)PARP8
SOURCE (Princeton)PARP8
Genetics Home Reference (NIH)PARP8
Genomic and cartography
GoldenPath hg38 (UCSC)PARP8  -     chr5:50666637-50846519 +  5q11.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PARP8  -     5q11.1   [Description]    (hg19-Feb_2009)
GoldenPathPARP8 - 5q11.1 [CytoView hg19]  PARP8 - 5q11.1 [CytoView hg38]
ImmunoBaseENSG00000151883
Genome Data Viewer NCBIPARP8 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK024961 AK225188 AK289369 AK298680 AK314466
RefSeq transcript (Entrez)NM_001178055 NM_001178056 NM_001331028 NM_024615
Consensus coding sequences : CCDS (NCBI)PARP8
Gene ExpressionPARP8 [ NCBI-GEO ]   PARP8 [ EBI - ARRAY_EXPRESS ]   PARP8 [ SEEK ]   PARP8 [ MEM ]
Gene Expression Viewer (FireBrowse)PARP8 [ Firebrowse - Broad ]
GenevisibleExpression of PARP8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79668
GTEX Portal (Tissue expression)PARP8
Human Protein AtlasENSG00000151883-PARP8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N3A8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N3A8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N3A8
Catalytic activity : Enzyme2.4.2.- [ Enzyme-Expasy ]   2.4.2.-2.4.2.- [ IntEnz-EBI ]   2.4.2.- [ BRENDA ]   2.4.2.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8N3A8
Domaine pattern : Prosite (Expaxy)PARP_CATALYTIC (PS51059)   
Domains : Interpro (EBI)Poly(ADP-ribose)pol_cat_dom   
Domain families : Pfam (Sanger)PARP (PF00644)   
Domain families : Pfam (NCBI)pfam00644   
Conserved Domain (NCBI)PARP8
SuperfamilyQ8N3A8
AlphaFold pdb e-kbQ8N3A8   
Human Protein Atlas [tissue]ENSG00000151883-PARP8 [tissue]
HPRD07960
Protein Interaction databases
DIP (DOE-UCLA)Q8N3A8
IntAct (EBI)Q8N3A8
BioGRIDPARP8
STRING (EMBL)PARP8
ZODIACPARP8
Ontologies - Pathways
QuickGOQ8N3A8
Ontology : AmiGONAD+ ADP-ribosyltransferase activity  intracellular anatomical structure  protein ADP-ribosylation  protein auto-ADP-ribosylation  protein mono-ADP-ribosylation  protein ADP-ribosylase activity  
Ontology : EGO-EBINAD+ ADP-ribosyltransferase activity  intracellular anatomical structure  protein ADP-ribosylation  protein auto-ADP-ribosylation  protein mono-ADP-ribosylation  protein ADP-ribosylase activity  
NDEx NetworkPARP8
Atlas of Cancer Signalling NetworkPARP8
Wikipedia pathwaysPARP8
Orthology - Evolution
OrthoDB79668
GeneTree (enSembl)ENSG00000151883
Phylogenetic Trees/Animal Genes : TreeFamPARP8
Homologs : HomoloGenePARP8
Homology/Alignments : Family Browser (UCSC)PARP8
Gene fusions - Rearrangements
Fusion : QuiverPARP8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARP8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARP8
dbVarPARP8
ClinVarPARP8
MonarchPARP8
1000_GenomesPARP8 
Exome Variant ServerPARP8
GNOMAD BrowserENSG00000151883
Varsome BrowserPARP8
ACMGPARP8 variants
VarityQ8N3A8
Genomic Variants (DGV)PARP8 [DGVbeta]
DECIPHERPARP8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPARP8 
Mutations
ICGC Data PortalPARP8 
TCGA Data PortalPARP8 
Broad Tumor PortalPARP8
OASIS PortalPARP8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARP8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPARP8
Mutations and Diseases : HGMDPARP8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPARP8
DgiDB (Drug Gene Interaction Database)PARP8
DoCM (Curated mutations)PARP8
CIViC (Clinical Interpretations of Variants in Cancer)PARP8
Cancer3DPARP8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPARP8
MedgenPARP8
Genetic Testing Registry PARP8
NextProtQ8N3A8 [Medical]
GENETestsPARP8
Target ValidationPARP8
Huge Navigator PARP8 [HugePedia]
ClinGenPARP8
Clinical trials, drugs, therapy
MyCancerGenomePARP8
Protein Interactions : CTDPARP8
Pharm GKB GenePA134903201
PharosQ8N3A8
Clinical trialPARP8
Miscellaneous
canSAR (ICR)PARP8
HarmonizomePARP8
DataMed IndexPARP8
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPARP8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:15:27 CEST 2021

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