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PARP8 (poly(ADP-ribose) polymerase family member 8)

Identity

Alias_symbol (synonym)FLJ21308
pART16
Other aliasARTD16
HGNC (Hugo) PARP8
LocusID (NCBI) 79668
Atlas_Id 71672
Location 5q11.1  [Link to chromosome band 5q11]
Location_base_pair Starts at 50665899 and ends at 50846522 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PARP8 (5q11.1) / LDAH (2p24.1)PARP8 (5q11.1) / PARP8 (5q11.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PARP8   26124
Cards
Entrez_Gene (NCBI)PARP8  79668  poly(ADP-ribose) polymerase family member 8
AliasesARTD16; pART16
GeneCards (Weizmann)PARP8
Ensembl hg19 (Hinxton)ENSG00000151883 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151883 [Gene_View]  chr5:50665899-50846522 [Contig_View]  PARP8 [Vega]
ICGC DataPortalENSG00000151883
TCGA cBioPortalPARP8
AceView (NCBI)PARP8
Genatlas (Paris)PARP8
WikiGenes79668
SOURCE (Princeton)PARP8
Genetics Home Reference (NIH)PARP8
Genomic and cartography
GoldenPath hg38 (UCSC)PARP8  -     chr5:50665899-50846522 +  5q11.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PARP8  -     5q11.1   [Description]    (hg19-Feb_2009)
EnsemblPARP8 - 5q11.1 [CytoView hg19]  PARP8 - 5q11.1 [CytoView hg38]
Mapping of homologs : NCBIPARP8 [Mapview hg19]  PARP8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK024961 AK225188 AK289369 AK298680 AK314466
RefSeq transcript (Entrez)NM_001178055 NM_001178056 NM_001331028 NM_024615
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PARP8
Cluster EST : UnigeneHs.369581 [ NCBI ]
CGAP (NCI)Hs.369581
Alternative Splicing GalleryENSG00000151883
Gene ExpressionPARP8 [ NCBI-GEO ]   PARP8 [ EBI - ARRAY_EXPRESS ]   PARP8 [ SEEK ]   PARP8 [ MEM ]
Gene Expression Viewer (FireBrowse)PARP8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79668
GTEX Portal (Tissue expression)PARP8
Human Protein AtlasENSG00000151883-PARP8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N3A8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N3A8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N3A8
Splice isoforms : SwissVarQ8N3A8
Catalytic activity : Enzyme2.4.2.30 [ Enzyme-Expasy ]   2.4.2.302.4.2.30 [ IntEnz-EBI ]   2.4.2.30 [ BRENDA ]   2.4.2.30 [ KEGG ]   
PhosPhoSitePlusQ8N3A8
Domaine pattern : Prosite (Expaxy)PARP_CATALYTIC (PS51059)   
Domains : Interpro (EBI)Poly(ADP-ribose)pol_cat_dom   
Domain families : Pfam (Sanger)PARP (PF00644)   
Domain families : Pfam (NCBI)pfam00644   
Conserved Domain (NCBI)PARP8
DMDM Disease mutations79668
Blocks (Seattle)PARP8
SuperfamilyQ8N3A8
Human Protein Atlas [tissue]ENSG00000151883-PARP8 [tissue]
Peptide AtlasQ8N3A8
HPRD07960
IPIIPI00964299   IPI00964996   IPI01009901   IPI00965301   IPI00966012   IPI00964062   IPI00964607   IPI00965507   IPI00967392   IPI00966191   IPI00965774   IPI00964832   IPI00966185   IPI00965484   IPI00966480   IPI00967939   
Protein Interaction databases
DIP (DOE-UCLA)Q8N3A8
IntAct (EBI)Q8N3A8
FunCoupENSG00000151883
BioGRIDPARP8
STRING (EMBL)PARP8
ZODIACPARP8
Ontologies - Pathways
QuickGOQ8N3A8
Ontology : AmiGONAD+ ADP-ribosyltransferase activity  intracellular  
Ontology : EGO-EBINAD+ ADP-ribosyltransferase activity  intracellular  
NDEx NetworkPARP8
Atlas of Cancer Signalling NetworkPARP8
Wikipedia pathwaysPARP8
Orthology - Evolution
OrthoDB79668
GeneTree (enSembl)ENSG00000151883
Phylogenetic Trees/Animal Genes : TreeFamPARP8
HOVERGENQ8N3A8
HOGENOMQ8N3A8
Homologs : HomoloGenePARP8
Homology/Alignments : Family Browser (UCSC)PARP8
Gene fusions - Rearrangements
Fusion: Tumor Portal PARP8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARP8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARP8
dbVarPARP8
ClinVarPARP8
1000_GenomesPARP8 
Exome Variant ServerPARP8
ExAC (Exome Aggregation Consortium)ENSG00000151883
GNOMAD BrowserENSG00000151883
Genetic variants : HAPMAP79668
Genomic Variants (DGV)PARP8 [DGVbeta]
DECIPHERPARP8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPARP8 
Mutations
ICGC Data PortalPARP8 
TCGA Data PortalPARP8 
Broad Tumor PortalPARP8
OASIS PortalPARP8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARP8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPARP8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PARP8
DgiDB (Drug Gene Interaction Database)PARP8
DoCM (Curated mutations)PARP8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PARP8 (select a term)
intoGenPARP8
Cancer3DPARP8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPARP8
Genetic Testing Registry PARP8
NextProtQ8N3A8 [Medical]
TSGene79668
GENETestsPARP8
Target ValidationPARP8
Huge Navigator PARP8 [HugePedia]
snp3D : Map Gene to Disease79668
BioCentury BCIQPARP8
ClinGenPARP8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79668
Chemical/Pharm GKB GenePA134903201
Clinical trialPARP8
Miscellaneous
canSAR (ICR)PARP8 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePARP8
EVEXPARP8
GoPubMedPARP8
iHOPPARP8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:21:45 CET 2017

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