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PARPBP (PARP1 binding protein)

Identity

Alias_namesC12orf48
chromosome 12 open reading frame 48
Alias_symbol (synonym)FLJ20641
PARI
Other aliasAROM
HGNC (Hugo) PARPBP
LocusID (NCBI) 55010
Atlas_Id 52559
Location 12q23.2  [Link to chromosome band 12q23]
Location_base_pair Starts at 102120171 and ends at 102197520 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PARPBP (12q23.2) / MYBPC1 (12q23.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  PARPBP/MYBPC1 (12q23)


External links

Nomenclature
HGNC (Hugo)PARPBP   26074
Cards
Entrez_Gene (NCBI)PARPBP  55010  PARP1 binding protein
AliasesAROM; C12orf48; PARI
GeneCards (Weizmann)PARPBP
Ensembl hg19 (Hinxton)ENSG00000185480 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185480 [Gene_View]  ENSG00000185480 [Sequence]  chr12:102120171-102197520 [Contig_View]  PARPBP [Vega]
ICGC DataPortalENSG00000185480
TCGA cBioPortalPARPBP
AceView (NCBI)PARPBP
Genatlas (Paris)PARPBP
WikiGenes55010
SOURCE (Princeton)PARPBP
Genetics Home Reference (NIH)PARPBP
Genomic and cartography
GoldenPath hg38 (UCSC)PARPBP  -     chr12:102120171-102197520 +  12q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PARPBP  -     12q23.2   [Description]    (hg19-Feb_2009)
EnsemblPARPBP - 12q23.2 [CytoView hg19]  PARPBP - 12q23.2 [CytoView hg38]
Mapping of homologs : NCBIPARPBP [Mapview hg19]  PARPBP [Mapview hg38]
OMIM613687   
Gene and transcription
Genbank (Entrez)AA757264 AF274940 AK000648 AK300041 AK302724
RefSeq transcript (Entrez)NM_001319988 NM_001319993 NM_001319994 NM_001319995 NM_001319996 NM_017915
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PARPBP
Cluster EST : UnigeneHs.330663 [ NCBI ]
CGAP (NCI)Hs.330663
Alternative Splicing GalleryENSG00000185480
Gene ExpressionPARPBP [ NCBI-GEO ]   PARPBP [ EBI - ARRAY_EXPRESS ]   PARPBP [ SEEK ]   PARPBP [ MEM ]
Gene Expression Viewer (FireBrowse)PARPBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55010
GTEX Portal (Tissue expression)PARPBP
Human Protein AtlasENSG00000185480-PARPBP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWS1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWS1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWS1
Splice isoforms : SwissVarQ9NWS1
PhosPhoSitePlusQ9NWS1
Domains : Interpro (EBI)P-loop_NTPase   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PARPBP
DMDM Disease mutations55010
Blocks (Seattle)PARPBP
SuperfamilyQ9NWS1
Human Protein Atlas [tissue]ENSG00000185480-PARPBP [tissue]
Peptide AtlasQ9NWS1
HPRD07937
IPIIPI00830041   IPI00830120   IPI00745962   IPI00448949   IPI00941876   IPI00647388   IPI00478557   IPI00871607   IPI00382479   IPI00942752   IPI00910252   IPI01010387   IPI01013170   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWS1
IntAct (EBI)Q9NWS1
FunCoupENSG00000185480
BioGRIDPARPBP
STRING (EMBL)PARPBP
ZODIACPARPBP
Ontologies - Pathways
QuickGOQ9NWS1
Ontology : AmiGOchromatin  DNA binding  protein binding  nucleoplasm  cytoplasm  DNA repair  negative regulation of double-strand break repair via homologous recombination  
Ontology : EGO-EBIchromatin  DNA binding  protein binding  nucleoplasm  cytoplasm  DNA repair  negative regulation of double-strand break repair via homologous recombination  
NDEx NetworkPARPBP
Atlas of Cancer Signalling NetworkPARPBP
Wikipedia pathwaysPARPBP
Orthology - Evolution
OrthoDB55010
GeneTree (enSembl)ENSG00000185480
Phylogenetic Trees/Animal Genes : TreeFamPARPBP
HOVERGENQ9NWS1
HOGENOMQ9NWS1
Homologs : HomoloGenePARPBP
Homology/Alignments : Family Browser (UCSC)PARPBP
Gene fusions - Rearrangements
Fusion : QuiverPARPBP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARPBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARPBP
dbVarPARPBP
ClinVarPARPBP
1000_GenomesPARPBP 
Exome Variant ServerPARPBP
ExAC (Exome Aggregation Consortium)ENSG00000185480
GNOMAD BrowserENSG00000185480
Varsome BrowserPARPBP
Genetic variants : HAPMAP55010
Genomic Variants (DGV)PARPBP [DGVbeta]
DECIPHERPARPBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPARPBP 
Mutations
ICGC Data PortalPARPBP 
TCGA Data PortalPARPBP 
Broad Tumor PortalPARPBP
OASIS PortalPARPBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARPBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPARPBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PARPBP
DgiDB (Drug Gene Interaction Database)PARPBP
DoCM (Curated mutations)PARPBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PARPBP (select a term)
intoGenPARPBP
Cancer3DPARPBP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613687   
Orphanet
DisGeNETPARPBP
MedgenPARPBP
Genetic Testing Registry PARPBP
NextProtQ9NWS1 [Medical]
TSGene55010
GENETestsPARPBP
Target ValidationPARPBP
Huge Navigator PARPBP [HugePedia]
snp3D : Map Gene to Disease55010
BioCentury BCIQPARPBP
ClinGenPARPBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55010
Chemical/Pharm GKB GenePA143485378
Clinical trialPARPBP
Miscellaneous
canSAR (ICR)PARPBP (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePARPBP
EVEXPARPBP
GoPubMedPARPBP
iHOPPARPBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:28:37 CET 2018

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