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PARS2 (prolyl-tRNA synthetase 2, mitochondrial (putative))

Identity

Alias_symbol (synonym)DKFZp727A071
Other aliasMT-PRORS
proRS
HGNC (Hugo) PARS2
LocusID (NCBI) 25973
Atlas_Id 71673
Location 1p32.3  [Link to chromosome band 1p32]
Location_base_pair Starts at 54756898 and ends at 54764553 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PARS2   30563
Cards
Entrez_Gene (NCBI)PARS2  25973  prolyl-tRNA synthetase 2, mitochondrial (putative)
AliasesMT-PRORS; proRS
GeneCards (Weizmann)PARS2
Ensembl hg19 (Hinxton)ENSG00000162396 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162396 [Gene_View]  chr1:54756898-54764553 [Contig_View]  PARS2 [Vega]
ICGC DataPortalENSG00000162396
TCGA cBioPortalPARS2
AceView (NCBI)PARS2
Genatlas (Paris)PARS2
WikiGenes25973
SOURCE (Princeton)PARS2
Genetics Home Reference (NIH)PARS2
Genomic and cartography
GoldenPath hg38 (UCSC)PARS2  -     chr1:54756898-54764553 -  1p32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PARS2  -     1p32.3   [Description]    (hg19-Feb_2009)
EnsemblPARS2 - 1p32.3 [CytoView hg19]  PARS2 - 1p32.3 [CytoView hg38]
Mapping of homologs : NCBIPARS2 [Mapview hg19]  PARS2 [Mapview hg38]
OMIM612036   
Gene and transcription
Genbank (Entrez)AK025585 AK289679 AL117473 BC007956 BC011758
RefSeq transcript (Entrez)NM_152268
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PARS2
Cluster EST : UnigeneHs.380169 [ NCBI ]
CGAP (NCI)Hs.380169
Alternative Splicing GalleryENSG00000162396
Gene ExpressionPARS2 [ NCBI-GEO ]   PARS2 [ EBI - ARRAY_EXPRESS ]   PARS2 [ SEEK ]   PARS2 [ MEM ]
Gene Expression Viewer (FireBrowse)PARS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25973
GTEX Portal (Tissue expression)PARS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L3T8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L3T8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L3T8
Splice isoforms : SwissVarQ7L3T8
Catalytic activity : Enzyme6.1.1.15 [ Enzyme-Expasy ]   6.1.1.156.1.1.15 [ IntEnz-EBI ]   6.1.1.15 [ BRENDA ]   6.1.1.15 [ KEGG ]   
PhosPhoSitePlusQ7L3T8
Domaine pattern : Prosite (Expaxy)AA_TRNA_LIGASE_II (PS50862)   
Domains : Interpro (EBI)aa-tRNA-synt_IIb    aa-tRNA-synth_II    Anticodon-bd    Pro-tRNA-ligase_IIa    ProRS_core_prok   
Domain families : Pfam (Sanger)HGTP_anticodon (PF03129)    tRNA-synt_2b (PF00587)   
Domain families : Pfam (NCBI)pfam03129    pfam00587   
Conserved Domain (NCBI)PARS2
DMDM Disease mutations25973
Blocks (Seattle)PARS2
SuperfamilyQ7L3T8
Human Protein AtlasENSG00000162396
Peptide AtlasQ7L3T8
HPRD13220
IPIIPI00553006   
Protein Interaction databases
DIP (DOE-UCLA)Q7L3T8
IntAct (EBI)Q7L3T8
FunCoupENSG00000162396
BioGRIDPARS2
STRING (EMBL)PARS2
ZODIACPARS2
Ontologies - Pathways
QuickGOQ7L3T8
Ontology : AmiGOproline-tRNA ligase activity  ATP binding  mitochondrial matrix  prolyl-tRNA aminoacylation  
Ontology : EGO-EBIproline-tRNA ligase activity  ATP binding  mitochondrial matrix  prolyl-tRNA aminoacylation  
Pathways : KEGGAminoacyl-tRNA biosynthesis   
NDEx NetworkPARS2
Atlas of Cancer Signalling NetworkPARS2
Wikipedia pathwaysPARS2
Orthology - Evolution
OrthoDB25973
GeneTree (enSembl)ENSG00000162396
Phylogenetic Trees/Animal Genes : TreeFamPARS2
HOVERGENQ7L3T8
HOGENOMQ7L3T8
Homologs : HomoloGenePARS2
Homology/Alignments : Family Browser (UCSC)PARS2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPARS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PARS2
dbVarPARS2
ClinVarPARS2
1000_GenomesPARS2 
Exome Variant ServerPARS2
ExAC (Exome Aggregation Consortium)PARS2 (select the gene name)
Genetic variants : HAPMAP25973
Genomic Variants (DGV)PARS2 [DGVbeta]
DECIPHERPARS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPARS2 
Mutations
ICGC Data PortalPARS2 
TCGA Data PortalPARS2 
Broad Tumor PortalPARS2
OASIS PortalPARS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPARS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPARS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PARS2
DgiDB (Drug Gene Interaction Database)PARS2
DoCM (Curated mutations)PARS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PARS2 (select a term)
intoGenPARS2
Cancer3DPARS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612036   
Orphanet
MedgenPARS2
Genetic Testing Registry PARS2
NextProtQ7L3T8 [Medical]
TSGene25973
GENETestsPARS2
Target ValidationPARS2
Huge Navigator PARS2 [HugePedia]
snp3D : Map Gene to Disease25973
BioCentury BCIQPARS2
ClinGenPARS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25973
Chemical/Pharm GKB GenePA142671198
Clinical trialPARS2
Miscellaneous
canSAR (ICR)PARS2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePARS2
EVEXPARS2
GoPubMedPARS2
iHOPPARS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:33:58 CEST 2017

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